Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Néstor L. Uzcátegui"'
Autor:
Jorge González-Bacerio, Irina Arocha, Mirtha Elisa Aguado, Yanira Méndez, Sabrina Marsiccobetre, Maikel Izquierdo, Daniel G. Rivera, Katherine Figarella, Néstor L. Uzcátegui
Publikováno v:
Life, Vol 11, Iss 10, p 1037 (2021)
Chagas disease, caused by the kinetoplastid parasite Trypanosoma cruzi, is a human tropical illness mainly present in Latin America. The therapies available against this disease are far from ideal. Proteases from pathogenic protozoan have been consid
Externí odkaz:
https://doaj.org/article/76ac9f2e5b3e4002a1b154edd177f810
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 589 (2019)
Brain aging is characterized by a chronic, low-grade inflammatory state, promoting deficits in cognition and the development of age-related neurodegenerative diseases. Malfunction of microglia, the brain-resident immune cells, was suggested to play a
Externí odkaz:
https://doaj.org/article/3bb0e609652b4abd81487c8011a13d27
Autor:
Néstor L. Uzcátegui, Katherine Figarella, Bjoern Bassarak, Nestor W. Meza, Rita Mukhopadhyay, Jose L. Ramirez, Michael Duszenko
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 4, Pp 880-888 (2013)
Background: Trypanosoma brucei is a primitive parasitic protozoan that thrives in diverse environments such as the midgut of the tsetse fly and the blood of a mammalian host. For an adequate adaptation to these environments, the parasite´s aquaglyce
Externí odkaz:
https://doaj.org/article/697803f67d9049ebb798351b4eb57578
Autor:
Peter J. Hotez, Maria Elena Bottazzi, Nelufa Yesmin Islam, Jungsoon Lee, Jeroen Pollet, Cristina Poveda, Ulrich Strych, Syamala Rani Thimmiraju, Nestor L. Uzcategui, Leroy Versteeg, Daniel Gorelick
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 535-545 (2024)
ABSTRACTIntroduction Zebrafishes represent a proven model for human diseases and systems biology, exhibiting physiological and genetic similarities and having innate and adaptive immune systems. However, they are underexplored for human vaccinology,
Externí odkaz:
https://doaj.org/article/7b5259018f2c4102869b765483e32b3f
Autor:
Syamala Rani Thimmiraju, Rakesh Adhikari, JeAnna R. Redd, Maria Jose Villar, Jungsoon Lee, Zhuyun Liu, Yi-Lin Chen, Suman Sharma, Amandeep Kaur, Nestor L. Uzcategui, Shannon E. Ronca, Wen-Hsiang Chen, Jason T. Kimata, Bin Zhan, Ulrich Strych, Maria Elena Bottazzi, Peter J. Hotez, Jeroen Pollet
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-5 (2024)
Abstract The development of broad-spectrum coronavirus vaccines is essential to prepare for future respiratory virus pandemics. We demonstrated broad neutralization by a trivalent subunit vaccine, formulating the receptor-binding domains of SARS-CoV,
Externí odkaz:
https://doaj.org/article/44e886df60de4b48bf25ffd2242f40b2
Autor:
Sabrina Marsiccobetre, Mirtha Elisa Aguado, Katherine Figarella, Yanira Méndez, Irina Arocha, Daniel G. Rivera, Néstor L. Uzcátegui, Jorge González-Bacerio, Maikel Izquierdo
Publikováno v:
Life, Vol 11, Iss 1037, p 1037 (2021)
Life
Volume 11
Issue 10
Life
Volume 11
Issue 10
Chagas disease, caused by the kinetoplastid parasite Trypanosoma cruzi, is a human tropical illness mainly present in Latin America. The therapies available against this disease are far from ideal. Proteases from pathogenic protozoan have been consid
Autor:
Alberto J. García, Alexis Rodríguez-Acosta, Elda E. Sánchez, Belsy Guerrero, Luis F. Navarrete, María I. Ramos, Néstor L. Uzcátegui, María E. Girón, Vanessa Padrón
Publikováno v:
Toxicon. 144:23-33
Bothrops venezuelensis snake venoms, from five localities in the North-Central Venezuelan regions, showed biochemical and haemostatic differences. In this study, bioactivities of B. venezuelensis venoms from different regions (Aragua state; Waraira R
Autor:
Florian Lang, Katherine Figarella, Sabrina Marsiccobetre, Alexis Rodríguez-Acosta, Néstor L. Uzcátegui
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1859:679-685
The boron element possesses a range of different effects on living beings. It is essential to beneficial at low concentrations, but toxic at excessive concentrations. Recently, some boron-based compounds have been identified as promising molecules ag
Autor:
Alexis Rodríguez-Acosta, Esteban Cuevas, Néstor L. Uzcátegui, Elda E. Sánchez, Chairat Atphaisit, Montamas Suntravat, Sara Lucena, Thomas J. Helmke
Publikováno v:
Toxicon. 122:43-49
Crotalid venoms are rich sources of components that affect the hemostatic system. Snake venom metalloproteinases are zinc-dependent enzymes responsible for hemorrhage that also interfere with hemostasis. The disintegrin domain is a part of snake veno
Publikováno v:
Microglia ISBN: 9781493996575
An extensive number of parasites are able to invade the central nervous system (CNS) and cause a plethora of pathologies. Microglia, the resident macrophages of nervous tissue, are responsible for the protection against intruders, and therefore, they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f2fda681d09b3a7240d40ffbcc2ec7b
https://doi.org/10.1007/978-1-4939-9658-2_11
https://doi.org/10.1007/978-1-4939-9658-2_11