Výsledky vyhledávání - "Nélida Leiva-Eriksson"

Akademický článek

Taming hemoglobin chemistry—a new hemoglobin-based oxygen carrier engineered with both decreased rates of nitric oxide scavenging and lipid oxidation

Autor: Chris E. Cooper, Michelle Simons, Alex Dyson, Nélida Leiva Eriksson, Gary G. A. Silkstone, Natalie Syrett, Victoria Allen-Baume, Leif Bülow, Luca Ronda, Andrea Mozzarelli, Mervyn Singer, Brandon J. Reeder

Publikováno v: Experimental and Molecular Medicine, Vol 56, Iss 10, Pp 2260-2270 (2024)

Abstract The clinical utility of hemoglobin-based oxygen carriers (HBOC) is limited by adverse heme oxidative chemistry. A variety of tyrosine residues were inserted on the surface of the γ subunit of recombinant fetal hemoglobin to create novel ele

Externí odkaz: https://doaj.org/article/cd598760871146708ad3bed058119767

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Akademický článek

Oxidative Implications of Substituting a Conserved Cysteine Residue in Sugar Beet Phytoglobin BvPgb 1.2

Autor: Simon Christensen, Leonard Groth, Nélida Leiva-Eriksson, Maria Nyblom, Leif Bülow

Publikováno v: Antioxidants, Vol 11, Iss 8, p 1615 (2022)

Phytoglobins (Pgbs) are plant-originating heme proteins of the globin superfamily with varying degrees of hexacoordination. Pgbs have a conserved cysteine residue, the role of which is poorly understood. In this paper, we investigated the functional

Externí odkaz: https://doaj.org/article/6bce6e6f542c4f8e8663b7b649c6c995

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Akademický článek

Improving Risk Assessment in the European Food Safety Authority: Lessons From the European Medicines Agency

Autor: Sevasti Chatzopoulou, Nélida Leiva Eriksson, Dennis Eriksson

Publikováno v: Frontiers in Plant Science, Vol 11 (2020)

The recent Regulation (EU) 2019/1381, published on the 6th September 2019, aims to improve the transparency and sustainability of the EU risk assessment in the food chain by amending the General Food Law Regulation (EC 178/2002) and a number of other

Externí odkaz: https://doaj.org/article/5a59368ed2234a60a37119c6048c1e66

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Oxidative Implications of Substituting a Conserved Cysteine Residue in Sugar Beet Phytoglobin BvPgb 1.2

Autor: Bülow, Simon Christensen, Leonard Groth, Nélida Leiva-Eriksson, Maria Nyblom, Leif

Publikováno v: Antioxidants; Volume 11; Issue 8; Pages: 1615

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::d1a2f99c844480c4eb1b0d59463aac56

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Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute

Autor: Leif Bülow, Andras Eke, Gary Silkstone, Thoufieq Shaik, Elizabeth M. Welbourn, Domokos Máthé, Nélida Leiva Eriksson, Svetlana Gretton, Natalie Syrett, Luca Ronda, Badri S. Rajagopal, Andrea Mozzarelli, Brandon J. Reeder, Chris E. Cooper, Michelle Simons

Publikováno v: Free Radical Biology & Medicine

Hemoglobin (Hb)-based oxygen carriers (HBOC) are modified extracellular proteins, designed to replace or augment the oxygen-carrying capacity of erythrocytes. However, clinical results have generally been disappointing due to adverse side effects, in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe49b1a96c2f1b63dafa6e8ecd7b22d3
http://europepmc.org/articles/PMC6597946

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Implementing an EU opt-in mechanism for GM crop cultivation

Autor: Eugénia de Andrade, Bernd van der Meulen, Joachim Schiemann, Nélida Leiva Eriksson, Tomasz Twardowski, Anneli Ritala, Piet van der Meer, Borut Bohanec, Roberto Defez, Tomáš Vaněk, Laszlo Sagi, Dennis Eriksson, Sevasti Chatzopoulou

Publikováno v: Eriksson, D, de Andrade, E, Bohanec, B, Chatzopoulou, S, Defez, R, Leiva Eriksson, N, van der Meer, P, van der Meulen, B, Ritala, A, Sági, L, Schiemann, J, Twardowski, T & Vaněk, T 2019, ' Implementing an EU opt-in mechanism for GM crop cultivation ', EMBO Reports, vol. 20, no. 5, e48036 . https://doi.org/10.15252/embr.201948036
EMBO reports
(2019). doi:10.15252/embr.201948036
info:cnr-pdr/source/autori:Dennis Eriksson Eugénia de Andrade Borut Bohanec Sevasti Chatzopoulou Roberto Defez Nélida Leiva Eriksson Piet van der Meer Bernd van der Meulen Anneli Ritala László Sági Joachim Schiemann Tomasz Twardowski and Tomá? Van?k/titolo:Implementing an EU opt-in mechanism for GM crop cultivation/doi:10.15252%2Fembr.201948036/rivista:EMBO reports (Print)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
EMBO Rep

EMBO Reports (2019) e48036 The cultivation of genetically modified (GM) crops in the EU remains a highly polemic issue. The only GM crop event that is currently authorised is the insect‐resistant maize “MON810”. The GM potato variety “Amflora

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c80e4d6e755164d4125d13751bcdcf
https://pub.epsilon.slu.se/16242/

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Improved production of human hemoglobin in yeast by engineering hemoglobin degradation

Autor: Olena P. Ishchuk, August T. Frost, Nathalie Laforge, José L. Martínez, Saki Matsumoto, Nélida Leiva Eriksson, Dina Petranovic, Facundo Muñiz-Paredes

Publikováno v: Ishchuk, O P, Frost, A T, Muñiz-Paredes, F, Matsumoto, S, Laforge, N, Eriksson, N L, Martínez, J L & Petranovic, D 2021, ' Improved production of human hemoglobin in yeast by engineering hemoglobin degradation ', Metabolic Engineering, vol. 66, pp. 259-267 . https://doi.org/10.1016/j.ymben.2021.05.002

With the increasing demand for blood transfusions, the production of human hemoglobin (Hb) from sustainable sources is increasingly studied. Microbial production is an attractive option, as it may provide a cheap, safe, and reliable source of this pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35192cf4d0b97ec05d1fc6cb02bd4c7d
https://pubmed.ncbi.nlm.nih.gov/33984513

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Electrochemical Characterization and Bioelectrocatalytic H2O2 Sensing of Non-Symbiotic Hexa-Coordinated Sugar Beet Hemoglobins

Autor: Leif Bülow, Elena E. Ferapontova, Nélida Leiva-Eriksson, Maciej Sosna

Publikováno v: Sosna, M, Leiva-Eriksson, N, Bülow, L & Ferapontova, E E 2020, ' Electrochemical Characterization and Bioelectrocatalytic H 2 O 2 Sensing of Non-Symbiotic Hexa-Coordinated Sugar Beet Hemoglobins ', ChemElectroChem, vol. 7, no. 9, pp. 2114-2122 . https://doi.org/10.1002/celc.202000358

The biological role of non-symbiotic plant hemoglobins (Hbs) is not well understood. It may involve sensing and signaling of reactive nitrogen and oxygen species–a property that can be used in electrochemical sensing. Here, we electrochemically stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6801cbdd49ca96eebb2b43edf5db0e
https://pure.au.dk/portal/da/publications/electrochemical-characterization-and-bioelectrocatalytic-h2o2-sensing-of-nonsymbiotic-hexacoordinated-sugar-beet-hemoglobins(b04c7768-2181-4822-8704-dfbd755c7f71).html

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Why the European Union needs a national GMO opt-in mechanism

Autor: Tomasz Twardowski, Joachim Schiemann, Anneli Ritala, Borut Bohanec, Sevasti Chatzopolou, Nélida Leiva Eriksson, Bernd van der Meulen, Laszlo Sagi, Piet van der Meer, Dennis Eriksson, Roberto Defez, Tomáš Vaněk, Eugénia de Andrade

Publikováno v: Nature Biotechnology 36 (2018) 1
Nature Biotechnology, 36(1), 18-19
Nature Biotechnology 39 (2020) 1
Roskilde University
Nature Biotechnology, 39(1), 115-115
Nature biotechnology
36 (2018). doi:10.1038/nbt.4051
info:cnr-pdr/source/autori:Dennis Eriksson, Eugénia de Andrade, Borut Bohanec, Sevasti Chatzopolou, Roberto Defez, Nélida Leiva Eriksson, Piet van der Meer, Bernd van der Meulen, Anneli Ritala, László Sági, Joachim Schiemann, Tomasz Twardowski & Tomá? Van?k/titolo:Why the European Union needs a national GMO opt-in mechanism/doi:10.1038%2Fnbt.4051/rivista:Nature biotechnology (Print)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:36

A correction to this paper has been published: https://doi.org/10.1038/s41587-020-00800-8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7845e464f92e39e130218f6c6df806ea
https://pubmed.ncbi.nlm.nih.gov/33339888

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Synthesis and characterization of epitope-imprinted polymers for purification of human hemoglobin

Autor: Leif Bülow, H. Bagán, Nélida Leiva Eriksson, Lei Ye, Tongchang Zhou

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname

One promising method to prepare protein-selective polymers is the epitope-imprinting approach, where surface-accessible peptides from a target protein are used as templates to create surface-exposed binding sites on molecularly imprinted polymers (MI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2900ee387ad86f1922fb86d0e4d6a2
https://doi.org/10.1039/c7ra07674f

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