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Disturbed metabolic pathways of air pollution-mediated mechanisms of cardiovascular disease and dietary opportunities: a scoping review

Autor: Healy, Darren, De Matteu, Constanza, Näätänen, Mari, Kårlund, Anna, Kolehmainen, Marjukka

Cardiovascular diseases (CVD) are the leading cause of death globally. Ambient particulate matter is one form of air pollution that was determined to contribute substantially to CVD burden. Diet is implicated in over 50% of all CVD-related deaths, wi

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LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases.

Autor: Ronkainen J; Center for Life Course Health Research, University of Oulu, Oulu, Finland., Nedelec R; Center for Life Course Health Research, University of Oulu, Oulu, Finland., Atehortua A; Artificial Intelligence in Medicine Lab (BCN-AIM), University of Barcelona, Barcelona, Spain.; Department of Mathematics and Computer Science, University of Barcelona, Barcelona, Spain., Balkhiyarova Z; Section of Statistical Multi-Omics, Department of Clinical and Experimental Medicine, School of Biosciences and Medicine, University of Surrey, Guildford, United Kingdom.; Section of Genetics and Genomics, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.; Bashkir State Medical University, Department of Endocrinology, Ufa, Russian Federation., Cascarano A; Artificial Intelligence in Medicine Lab (BCN-AIM), University of Barcelona, Barcelona, Spain.; Department of Mathematics and Computer Science, University of Barcelona, Barcelona, Spain., Ngoc Dang V; Artificial Intelligence in Medicine Lab (BCN-AIM), University of Barcelona, Barcelona, Spain.; Department of Mathematics and Computer Science, University of Barcelona, Barcelona, Spain., Elhakeem A; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom., van Enckevort E; Department of Genetics and Genomics Coordination Center, University of Groningen, Groningen, the Netherlands., Goncalves Soares A; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom., Haakma S; Department of Genetics and Genomics Coordination Center, University of Groningen, Groningen, the Netherlands., Halonen M; Center for Life Course Health Research, University of Oulu, Oulu, Finland., Heil KF; Artificial Intelligence in Medicine Lab (BCN-AIM), University of Barcelona, Barcelona, Spain.; Department of Mathematics and Computer Science, University of Barcelona, Barcelona, Spain., Heiskala A; Center for Life Course Health Research, University of Oulu, Oulu, Finland., Hyde E; Department of Genetics and Genomics Coordination Center, University of Groningen, Groningen, the Netherlands., Jacquemin B; University of Rennes, INSERM, School of Advanced Studies in Public Health (EHESP), Research Institute for Environmental and Occupational Health, UMR_S 1085, Rennes, France., Keikkala E; Finnish Institute for Health and Welfare, Population Health Unit, Helsinki and Oulu, Finland.; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Kerckhoffs J; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands., Klåvus A; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Kopinska JA; Department of Social Sciences and Economics, Sapienza University of Rome, Rome, Italy., Lepeule J; Grenoble Alpes University, INSERM, CNRS, Institute for Advanced Biosciences, Grenoble, France., Marazzi F; CEIS Tor Vergata, Centre for Economic and International Studies, University of Rome Tor Vergata, Rome, Italy., Motoc I; Amsterdam UMC, Epidemiology and Data Science, University of Amsterdam, Amsterdam Public Health, Amsterdam, the Netherlands., Näätänen M; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Ribbenstedt A; Division of Food and Nutrition Science, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden., Rundblad A; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Blindern, Oslo, Norway., Savolainen O; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.; Division of Food and Nutrition Science, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.; Department of Biology and Biological Engineering, Chalmers Mass Spectrometry Infrastructure, Chalmers University of Technology, Gothenburg, Sweden., Simonetti V; R&D Department, Ab.Acus srl, Milan, Italy., de Toro Eadie N; School of Public Health, Department of Epidemiology and Biostatistics, Imperial College London, St. Mary's Hospital, London, United Kingdom., Tzala E; School of Public Health, Department of Epidemiology and Biostatistics, Imperial College London, St. Mary's Hospital, London, United Kingdom., Ulrich A; Section of Statistical Multi-Omics, Department of Clinical and Experimental Medicine, School of Biosciences and Medicine, University of Surrey, Guildford, United Kingdom., Wright T; School of Public Health, Department of Epidemiology and Biostatistics, Imperial College London, St. Mary's Hospital, London, United Kingdom., Zarei I; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., d'Amico E; R&D Department, Ab.Acus srl, Milan, Italy., Belotti F; CEIS Tor Vergata, Centre for Economic and International Studies, University of Rome Tor Vergata, Rome, Italy.; Department of Economics and Finance, University of Rome Tor Vergata, Rome, Italy., Brunius C; Division of Food and Nutrition Science, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden., Castleton C; CyNexo srl, Trivignano Udinese, Italy., Charles MA; Center for Research in Epidemiology and Statistics, INSERM, INRAE, University of Paris, Paris, France.; Ined, INSERM, EFS, Elfe Joint Unit, Aubervilliers, France., Gaillard R; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Hanhineva K; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Biochemistry, University of Turku, Turku, Finland., Hoek G; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands., Holven KB; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Blindern, Oslo, Norway.; National Advisory Unit on Familial Hypercholesterolemia, Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway., Jaddoe VWV; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Kaakinen MA; Section of Statistical Multi-Omics, Department of Clinical and Experimental Medicine, School of Biosciences and Medicine, University of Surrey, Guildford, United Kingdom.; Section of Genetics and Genomics, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom., Kajantie E; Finnish Institute for Health and Welfare, Population Health Unit, Helsinki and Oulu, Finland.; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Kavousi M; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Lakka T; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Matthews J; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Blindern, Oslo, Norway., Piano Mortari A; CEIS Tor Vergata, Centre for Economic and International Studies, University of Rome Tor Vergata, Rome, Italy., Vääräsmäki M; Finnish Institute for Health and Welfare, Population Health Unit, Helsinki and Oulu, Finland.; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Voortman T; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Webster C; Beta Technology Ltd, Doncaster, United Kingdom., Zins M; Population-based Epidemiological Cohorts Unit, INSERM UMS 11, Villejuif, France., Atella V; CEIS Tor Vergata, Centre for Economic and International Studies, University of Rome Tor Vergata, Rome, Italy.; Department of Economics and Finance, University of Rome Tor Vergata, Rome, Italy.; Stanford University, Stanford, CA., Bulgheroni M; R&D Department, Ab.Acus srl, Milan, Italy., Chadeau-Hyam M; School of Public Health, Department of Epidemiology and Biostatistics, Imperial College London, St. Mary's Hospital, London, United Kingdom., Conti G; Department of Economics, University College London, London, United Kingdom.; Social Research Institute, London, United Kingdom., Evans J; Beta Technology Ltd, Doncaster, United Kingdom., Felix JF; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Heude B; Center for Research in Epidemiology and Statistics, INSERM, INRAE, University of Paris, Paris, France., Järvelin MR; Center for Life Course Health Research, University of Oulu, Oulu, Finland.; School of Public Health, Department of Epidemiology and Biostatistics, Imperial College London, St. Mary's Hospital, London, United Kingdom., Kolehmainen M; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Landberg R; Division of Food and Nutrition Science, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden., Lekadir K; Artificial Intelligence in Medicine Lab (BCN-AIM), University of Barcelona, Barcelona, Spain.; Department of Mathematics and Computer Science, University of Barcelona, Barcelona, Spain., Parusso S; CyNexo srl, Trivignano Udinese, Italy., Prokopenko I; Section of Statistical Multi-Omics, Department of Clinical and Experimental Medicine, School of Biosciences and Medicine, University of Surrey, Guildford, United Kingdom.; UMR 8199-EGID, Institut Pasteur de Lille, CNRS, University of Lille, Lille, France.; Institute of Biochemistry and Genetics, Ufa Federal Research Centre Russian Academy of Sciences, Ufa, Russian Federation., de Rooij SR; Amsterdam UMC, Epidemiology and Data Science, University of Amsterdam, Amsterdam Public Health, Amsterdam, the Netherlands., Roseboom T; Amsterdam UMC, Epidemiology and Data Science, University of Amsterdam, Amsterdam Public Health, Amsterdam, the Netherlands.; Gynaecology and Obstetrics, Amsterdam Reproduction and Development Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Swertz M; Department of Genetics and Genomics Coordination Center, University of Groningen, Groningen, the Netherlands., Timpson N; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom., Ulven SM; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Blindern, Oslo, Norway., Vermeulen R; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands.; Julius Center, University Medical Center Utrecht, Utrecht, the Netherlands., Juola T; Center for Life Course Health Research, University of Oulu, Oulu, Finland., Sebert S; Center for Life Course Health Research, University of Oulu, Oulu, Finland.

Publikováno v: Environmental epidemiology (Philadelphia, Pa.) [Environ Epidemiol] 2021 Dec 28; Vol. 6 (1), pp. e184. Date of Electronic Publication: 2021 Dec 28 (Print Publication: 2022).