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Publikováno v:
Proceedings of the National Academy of Sciences. 91:8329-8333
The mos protooncogene has opposing effects on cell cycle progression. It is required for reinitiation of meiotic maturation and for meiotic progression through metaphase II, yet it is an active component of cytostatic factor. mos is a potent oncogene
Publikováno v:
Molecular and Cellular Biology. 13:2546-2553
Several protein kinases, including Mos, maturation-promoting factor (MPF), mitogen-activated protein (MAP) kinase, and MAP kinase kinase (MAPKK), are activated when Xenopus oocytes enter meiosis. De novo synthesis of the Mos protein is required for p
Publikováno v:
Current Opinion in Genetics & Development. 3:19-25
The product of the mos proto-oncogene is a serine/threonine kinase that is expressed at high levels in germ cells. Mos is a regulator of meiotic maturation, and is required for the initiation and progression of oocyte meiotic maturation that leads to
Publikováno v:
The Journal of Cell Biology
Scopus-Elsevier
Scopus-Elsevier
The relationship between the mos protooncogene protein and cAMP-dependent protein kinase (PKA) during the maturation of Xenopus oocytes was investigated. Microinjection of the PKA catalytic subunit (PKAc) into Xenopus oocytes inhibited oocyte maturat
Publikováno v:
Nature. 355:649-652
WHEN fully grown Xenopus oocytes are stimulated by progesterone, a period of protein synthesis is necessary for maturation1. Synthesis of the mos proto-oncogene product, pp39mos is necessary for the activation of M-phase promoting factor (MPF) in mei
mos Gene Transforming Efficiencies Correlate with Oocyte Maturation and Cytostatic Factor Activities
Publikováno v:
Molecular and Cellular Biology. 11:604-610
The mos proto-oncogenes from different vertebrate species transform mouse NIH 3T3 cells with markedly different efficiencies. v-mos, mouse (c-mosmu), and chicken (c-mosch) mos transform NIH 3T3 cells 10- to 100-fold more efficiently than do human (c-
Autor:
Woude Vande, J J Eppig, R Buccione, N Yew, Marianne Oskarsson, R Paules, I Daar, Noriyuki Sagata
Publikováno v:
Ciba Foundation Symposium 150-Proto-Oncogenes in Cell Development
Maturation promoting factor (MPF) is a cytoplasmic activity that causes oocytes arrested in prophase to resume meiosis. An inactive form of MPF termed pre-MPF exists in fully grown oocytes. In Xenopus oocytes, progesterone induces maturation and pre-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e90da690114bb86de0faedb0a2afd87
https://doi.org/10.1002/9780470513927.ch10
https://doi.org/10.1002/9780470513927.ch10
Autor:
A R Nebreda, Eugenio Santos, N Yew, I Daar, Michael Wigler, Richard S. Paules, Philip M. Sass, G F Vande Woude
Publikováno v:
Science (New York, N.Y.). 253(5015)
The endogenous mos proto-oncogene product (Mos) is required for meiotic maturation. In Xenopus oocytes, the ras oncogene product (Ras) can induce meiotic maturation and high levels of M-phase--promoting factor (MPF) independent of endogenous Mos, ind
Autor:
G F, Vande Woude, R, Buccione, I, Daar, J J, Eppig, M, Oskarsson, R, Paules, N, Sagata, N, Yew
Publikováno v:
Ciba Foundation symposium. 150
Maturation promoting factor (MPF) is a cytoplasmic activity that causes oocytes arrested in prophase to resume meiosis. An inactive form of MPF termed pre-MPF exists in fully grown oocytes. In Xenopus oocytes, progesterone induces maturation and pre-