Zobrazeno 1 - 10
of 703
pro vyhledávání: '"N, Schechter"'
Autor:
Supranee Upanan, Jeeyoung Lee, Khalid J. Tunau-Spencer, Praveen K. Rajvanshi, Elizabeth C. Wright, Constance T. Noguchi, Alan N. Schechter
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Introduction:Nitric oxide (NO) is a vasodilator gas that plays a critical role in mitochondrial respiration and skeletal muscle function. NO is endogenously generated by NO synthases: neuronal NO synthase (nNOS), endothelial NO synthase (eNOS), or in
Externí odkaz:
https://doaj.org/article/8139321c163144a4bef027cdf70e799b
Autor:
Ji Won Park, Barbora Piknova, Peter J. Walter, Hongyi Cai, Supranee Upanan, Samantha M. Thomas, Khalid J. Tunau-Spencer, Alan N. Schechter
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The reduction pathway of nitrate (NO3 −) and nitrite (NO2 −) to nitric oxide (NO) contributes to regulating many physiological processes. To examine the rate and extent of dietary nitrate absorption and its reduction to nitrite, we suppl
Externí odkaz:
https://doaj.org/article/3f3f4df9779c46088890810db4936b16
Autor:
Barbora Piknova, Mary N. Woessner, Joaquin Ortiz deZevallos, William E. Kraus, Mitch D. VanBruggen, Alan N. Schechter, Jason D. Allen
Publikováno v:
Physiological Reports, Vol 10, Iss 23, Pp n/a-n/a (2022)
Abstract Skeletal muscle may act as a reservoir for N‐oxides following inorganic nitrate supplementation. This idea is most intriguing in individuals with peripheral artery disease (PAD) who are unable to endogenously upregulate nitric oxide. This
Externí odkaz:
https://doaj.org/article/d5f16daba0eb4ceb9ec9492d93c7ca50
Autor:
Ji Won Park, Barbora Piknova, Audrey Jenkins, David Hellinga, Leonard M. Parver, Alan N. Schechter
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Nitric oxide (NO) signaling has been studied in the eye, including in the pathophysiology of some eye diseases. While NO production by nitric oxide synthase (NOS) enzymes in the eye has been characterized, the more recently described pathway
Externí odkaz:
https://doaj.org/article/eb8fa08fe96a4ad3b15f0f7cf0166ef2
Autor:
Gustavo H. Oliveira-Paula, Lucas C. Pinheiro, Danielle A. Guimaraes, Sandra O. Conde Tella, Ana L. Furlan Blanco, Celio D. Angelis, Alan N. Schechter, Jose E. Tanus-Santos
Publikováno v:
Redox Biology, Vol 8, Iss C, Pp 398-406 (2016)
Upregulation of xanthine oxidoreductase (XOR) increases vascular reactive oxygen species (ROS) levels and contributes to nitroso-redox imbalance. However, XOR can generate nitric oxide (NO) from nitrite, and increased superoxide could inactivate NO f
Externí odkaz:
https://doaj.org/article/bd40bf3d113440a790b9367e99d26a7e
Autor:
Stefan Kadach, Ji Won Park, Zdravko Stoyanov, Matthew I. Black, Anni Vanhatalo, Mark Burnley, Peter J. Walter, Hongyi Cai, Alan N. Schechter, Barbora Piknova, Andrew M. Jones
Publikováno v:
Acta Physiologica. 237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afa15a62d7fc33a44147650ff9e6741f
https://doi.org/10.1111/apha.13924
https://doi.org/10.1111/apha.13924
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193747 (2018)
Nitrite is recognized as a bioactive nitric oxide (NO) metabolite. We have shown that nitrite inhibits platelet activation and increases platelet cGMP levels in the presence of partially deoxygenated erythrocytes. In this study, we investigated the e
Externí odkaz:
https://doaj.org/article/99b7475a9d9a43599ee9c54da4dcf6da
Autor:
Attaphon Chamchoi, Sirada Srihirun, Kittiphong Paiboonsukwong, Thanaporn Sriwantana, Piyadon Sathavorasmith, Kovit Pattanapanyasat, Rhoda Elison Hirsch, Alan N Schechter, Nathawut Sibmooh
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203955 (2018)
Nitric oxide (NO) can be generated from nitrite by reductase activity of deoxygenated hemoglobin (deoxyHb) apparently to facilitate tissue perfusion under hypoxic condition. Although hemoglobin E (HbE) solutions have been shown to exhibit decreased r
Externí odkaz:
https://doaj.org/article/4f740964af3645c581c9796463e4f1fb
Publikováno v:
Exerc Sport Sci Rev
Non-enzymatic nitric oxide (NO) generation via the reduction of nitrate and nitrite ions, along with remarkably high levels of nitrate ions in skeletal muscle, have been recently described. Skeletal muscle nitrate storage may be critical for maintena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75fb1b900196158a1f38e4f8f33f946
https://doi.org/10.1249/jes.0000000000000272
https://doi.org/10.1249/jes.0000000000000272
Publikováno v:
Nitric Oxide
The roles of nitrate and nitrite ions as nitric oxide (NO) sources in mammals, complementing NOS enzymes, have recently been the focus of much research. We previously reported that rat skeletal muscle serves as a nitrate reservoir, with the amount of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f8e76c557215139406c7b6a223d7d1
https://doi.org/10.1016/j.niox.2021.03.003
https://doi.org/10.1016/j.niox.2021.03.003