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CXCL14 is a candidate biomarker for Hedgehog signalling in idiopathic pulmonary fibrosis

Autor: Joseph R. Arron, Ivan Peng, Jason DeVoss, Harold R. Collard, Alexander R. Abbas, Elsa N N'Diaye, Paul J. Wolters, Guiquan Jia, Murat Yaylaoglu, Jackson G. Egen, Daryle Depianto, Sanjay Chandriani, Heather M. Moore

Publikováno v: Thorax. 72(9)

Background Idiopathic pulmonary fibrosis (IPF) is associated with aberrant expression of developmental pathways, including Hedgehog (Hh). As Hh signalling contributes to multiple pro-fibrotic processes, Hh inhibition may represent a therapeutic optio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9e6a7ea185b4c54a7d4ef05fdf5854
https://pubmed.ncbi.nlm.nih.gov/28250200

Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis

Autor: Paul J. Wolters, Jasleen Kukreja, Satyajit K Karnik, Daryle Depianto, Alexander R. Abbas, Harold R. Collard, Sabyasachi Biswas, Steven E. Kauder, Connie Ha, Elsa N N'Diaye, Guiquan Jia, Zora Modrusan, Patrick Caplazi, Michael A. Matthay, Sanjay Chandriani, Jackson G. Egen, Joseph R. Arron

Publikováno v: DePianto, DJ; Chandriani, S; Abbas, AR; Jia, G; N'Diaye, EN; Caplazi, P; et al.(2015). Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis. Thorax, 70(1), 48-56. doi: 10.1136/thoraxjnl-2013-204596. UCSF: Retrieved from: http://www.escholarship.org/uc/item/20x7s6cx
Thorax, vol 70, iss 1

© 2014, BMJ Publishing Group. All rights reserved. Background: There is microscopic spatial and temporal heterogeneity of pathological changes in idiopathic pulmonary fibrosis (IPF) lung tissue, which may relate to heterogeneity in pathophysiologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb45eac670e916b08f9cb61cc7a1055
http://www.escholarship.org/uc/item/20x7s6cx

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Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele

Autor: Jeff Lutman, Henry R. Maun, Elaine Mai, Susan M. Sa, Navneet Ratti, Mary E. Keir, Elsa N N'Diaye, Jackson G. Egen, Eric Stefanich, Steven E. Kauder, Amitabha Chaudhuri, Elizabeth Luis, Lydia Santell, William A. Faubion, Judy Young, Robert A. Lazarus, Lino C. Gonzalez, Robert R. Graham, Lilyan Wright, Lauri Diehl

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e83958 (2013)

Background Macrophage stimulating protein (MSP) is a serum growth factor that binds to and activates the receptor tyrosine kinase, Recepteur d'Origine Nantais (RON). A non-synonymous coding variant in MSP (689C) has been associated with genetic susce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500a717e8b536c8cb20b8a42fc08e643
https://pubmed.ncbi.nlm.nih.gov/24409221