Zobrazeno 1 - 10
of 150
pro vyhledávání: '"N, Lipke"'
Autor:
Dhara Malavia-Jones, Rhys A. Farrer, Mark H.T. Stappers, Matt B. Edmondson, Andrew M. Borman, Elizabeth M. Johnson, Peter N. Lipke, Neil A.R. Gow
Publikováno v:
The Cell Surface, Vol 10, Iss , Pp 100110- (2023)
Candida auris is a multi-drug resistant human fungal pathogen that has become a global threat to human health due to its drug resistant phenotype, persistence in the hospital environment and propensity for patient to patient spread. Isolates display
Externí odkaz:
https://doaj.org/article/474986532a0e407591e01236194ffe25
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Candida Als family adhesins mediate adhesion to biological and abiotic substrates, as well as fungal cell aggregation, fungal-bacterial co-aggregation and biofilm formation. The activity of at least two family members, Als5 and Als1, is dependent on
Externí odkaz:
https://doaj.org/article/24853ede8f134fe4b96affab53b18bcc
Autor:
Peter N. Lipke, Peleg Ragonis-Bachar
Publikováno v:
Journal of Fungi, Vol 9, Iss 4, p 419 (2023)
Bacterial and fungal adhesins mediate microbial aggregation, biofilm formation, and adhesion to host. We divide these proteins into two major classes: professional adhesins and moonlighting adhesins that have a non-adhesive activity that is evolution
Externí odkaz:
https://doaj.org/article/abd5c417a9e14af9a916a258c631989f
Single-cell fluidic force microscopy reveals stress-dependent molecular interactions in yeast mating
Autor:
Marion Mathelié-Guinlet, Felipe Viela, Jérôme Dehullu, Sviatlana Filimonava, Jason M. Rauceo, Peter N. Lipke, Yves F. Dufrêne
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Mathelié-Guinlet et al. investigate the molecular binding mechanisms of sexual agglutinins in budding yeast Saccharomyces cerevisiae. They report that mechanical tension enhances the strength of agglutinin interactions, supporting a new model in whi
Externí odkaz:
https://doaj.org/article/d982771433c549ee97383aaeb1e7498c
Autor:
Stephen A. Klotz, Peter N. Lipke
Publikováno v:
Pathogens, Vol 11, Iss 11, p 1304 (2022)
Serum amyloid P component (SAP) may play an important role in human fungal diseases. SAP binds to functional amyloid on the fungal surface and masks fungi from host immune processes, skewing the macrophage population from the pro-inflammatory M1 to t
Externí odkaz:
https://doaj.org/article/3dcce6fa6c3a476883c5db98fcef9b2b
Publikováno v:
Pathogens, Vol 11, Iss 9, p 1000 (2022)
Candida-macrophage interactions are important immune defense responses associated with disseminated and deep-seated candidiasis in humans. Cells of Candida spp. express functional amyloids on their surfaces during the pathogenesis of disseminated can
Externí odkaz:
https://doaj.org/article/3000d2a54ec0496aba30c435fe7a94c3
Publikováno v:
The Cell Surface, Vol 6, Iss , Pp 100045- (2020)
Proteins are secreted from eukaryotic cells by several mechanisms besides the well-characterized classical secretory system. Proteins destined to enter the classical secretory system contain a signal peptide for translocation into the endoplasmic ret
Externí odkaz:
https://doaj.org/article/89ab18eabe9a4832b1d9c8dc3aed6b9c
Publikováno v:
mSphere, Vol 5, Iss 6 (2020)
ABSTRACT In yeast, many proteins are found in both the cytoplasmic and extracellular compartments, and consequently it can be difficult to distinguish nonconventional secretion from cellular leakage. Therefore, we monitored the extracellular glyceral
Externí odkaz:
https://doaj.org/article/7398c0bbe6734ee3ac3301bb9cbe4827
Publikováno v:
Pathogens, Vol 10, Iss 8, p 1013 (2021)
Amyloid structures assemble through a repeating type of bonding called “cross-β”, in which identical sequences in many protein molecules form β-sheets that interdigitate through side chain interactions. We review the structural characteristics
Externí odkaz:
https://doaj.org/article/9dc35eb41cdd4c9e9e504b55499e7fd3
Autor:
Vida Ho, Philippe Herman-Bausier, Christopher Shaw, Karen A. Conrad, Melissa C. Garcia-Sherman, Jeremy Draghi, Yves F. Dufrene, Peter N. Lipke, Jason M. Rauceo
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT The human fungal commensal Candida albicans can become a serious opportunistic pathogen in immunocompromised hosts. The C. albicans cell adhesion protein Als1p is a highly expressed member of a large family of paralogous adhesins. Als1p can
Externí odkaz:
https://doaj.org/article/417fa0c7130d4adc9535ba8c456b7443