Zobrazeno 1 - 10
of 2 389
pro vyhledávání: '"N, Keller"'
Autor:
Ekaterina E. Kopylova, Margarita F. Botsieva, Kristina I. Berezovskaya, Sultan M. Kunakkuzin, Alina D. Mikhailova, Anastasiya V. Konova, Anna O. Dasko, Gul’emesh A. Valeeva, Olga S. Ispiryan, Diana A. Sverchkova, Karina N. Keller, Alisa E. Dovgiy
Publikováno v:
Педиатрическая фармакология, Vol 20, Iss 6 (2023)
The obesity prevalence in children has increased dramatically over the past four decades and has epidemic nature. Lifestyle correction in majority of obese children and adolescents leads only to slight success in reducing body weight (that usually re
Externí odkaz:
https://doaj.org/article/f3eb25fd40f446aa8f323d7fed6b6ca4
Autor:
Liz A. Aguilar, Caitlin R. Coker, Zari McCullers, Alexandra Evans, Opeyemi Showemimo, Mariam Melkumyan, Bailey N. Keller, Angela E. Snyder, Sarah S. Bingaman, Patrick A. Randall, Andras Hajnal, Kirsteen N. Browning, Amy C. Arnold, Yuval Silberman
Publikováno v:
Addiction Neuroscience, Vol 9, Iss , Pp 100132- (2023)
Alcohol use disorders (AUDs) are common mental health issues worldwide and can lead to other chronic diseases. Stress is a major factor in the development and continuation of AUDs, and adolescent alcohol exposure can lead to enhanced stress-responsiv
Externí odkaz:
https://doaj.org/article/839214cf3b53462397c704b5e9f17384
Autor:
Amanda N. Szabo‐Reed, Tristyn Hall, Eric D. Vidoni, Angela Van Sciver, Monica Sewell, Jeffrey M. Burns, C. Munro Cullum, William P. Gahan, Linda S. Hynan, Diana R. Kerwin, Heidi Rossetti, Ann M. Stowe, Wanpen Vongpatanasin, David C. Zhu, Rong Zhang, Jeffrey N. Keller, Ellen F. Binder
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 9, Iss 4, Pp n/a-n/a (2023)
Abstract INTRODUCTION The risk reduction for Alzheimer's disease (rrAD) trial was a multisite clinical trial to assess exercise and intensive vascular pharmacological treatment on cognitive function in community‐dwelling older adults at increased r
Externí odkaz:
https://doaj.org/article/76e17e8719694a40a6deed1b1495c499
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2322 (2024)
Fibrosis is a chronic pathology resulting from excessive deposition of extracellular matrix components that leads to the loss of tissue function. Pulmonary fibrosis can follow a variety of diverse insults including ischemia, respiratory infection, or
Externí odkaz:
https://doaj.org/article/c3e1af6bff26482593221ec4a71930e1
Autor:
Helen Wong, Jordan M. Buck, Curtis Borski, Jessica T. Pafford, Bailey N. Keller, Ryan A. Milstead, Jessica L. Hanson, Jerry A. Stitzel, Charles A. Hoeffer
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-23 (2022)
Abstract Background Regulator of calcineurin 1 (RCAN1) is overexpressed in Down syndrome (DS), but RCAN1 levels are also increased in Alzheimer’s disease (AD) and normal aging. AD is highly comorbid among individuals with DS and is characterized in
Externí odkaz:
https://doaj.org/article/5bb79d8910314ac5a630b405cad468f8
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16901 (2023)
Antibody-based cancer drugs that target the checkpoint proteins CTLA-4, PD-1 and PD-L1 provide marked improvement in some patients with deadly diseases such as lung cancer and melanoma. However, most patients are either unresponsive or relapse follow
Externí odkaz:
https://doaj.org/article/b0de19537b214e8f865dfac4dd2f3f38
Autor:
Giuseppe Deganutti, Yi-Lynn Liang, Xin Zhang, Maryam Khoshouei, Lachlan Clydesdale, Matthew J. Belousoff, Hari Venugopal, Tin T. Truong, Alisa Glukhova, Andrew N. Keller, Karen J. Gregory, Katie Leach, Arthur Christopoulos, Radostin Danev, Christopher A. Reynolds, Peishen Zhao, Patrick M. Sexton, Denise Wootten
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The glucagon-like peptide-1 receptor (GLP-1R) can be targeted in the treatment of diabetes, obesity and other metabolic disorders. Here, the authors assess the molecular mechanisms of peptide agonists binding to GLP-1R and the responses elucidated by
Externí odkaz:
https://doaj.org/article/8f7e8894b23a4f8eb32f5d2c26ccefc6
Autor:
Norman Scheel, Jeffrey N. Keller, Ellen F. Binder, Eric D. Vidoni, Jeffrey M. Burns, Binu P. Thomas, Ann M. Stowe, Linda S. Hynan, Diana R. Kerwin, Wanpen Vongpatanasin, Heidi Rossetti, C. Munro Cullum, Rong Zhang, David C. Zhu
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Subject motion is a well-known confound in resting-state functional MRI (rs-fMRI) and the analysis of functional connectivity. Consequently, several clean-up strategies have been established to minimize the impact of subject motion. Physiological sig
Externí odkaz:
https://doaj.org/article/1a604aabcc2a46b7a6d247b7a8afaf82
Autor:
Candida J. Rebello, Stephen Boué, Ronald J. Levy, Renée Puyau, Robbie A. Beyl, Frank L. Greenway, Mark L. Heiman, Jeffrey N. Keller, Charles F. Reynolds, John P. Kirwan
Publikováno v:
Nutrients, Vol 15, Iss 8, p 1920 (2023)
Soybean products have nutrients, dietary fiber, and phytoalexins beneficial for cardiovascular and overall health. Despite their high consumption in Asian populations, their safety in Western diets is debated. We conducted a dose-escalating clinical
Externí odkaz:
https://doaj.org/article/8afc601723cb4c03a5bae74907c8bbc2
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
The neurobiological mechanisms that regulate the development and maintenance of alcohol use disorder (AUD) are complex and involve a wide variety of within and between systems neuroadaptations. While classic reward, preoccupation, and withdrawal neur
Externí odkaz:
https://doaj.org/article/dacaee3053564252a12423cab44bc76e