Zobrazeno 1 - 10
of 567
pro vyhledávání: '"N, Kammer"'
Cancer-associated fibroblasts in early-stage lung adenocarcinoma correlate with tumor aggressiveness
Autor:
Georgii Vasiukov, Yong Zou, Maria-Fernanda Senosain, Jamshedur S. M. Rahman, Sanja Antic, Katherine M. Young, Eric L. Grogan, Michael N. Kammer, Fabien Maldonado, Cynthia A. Reinhart-King, Pierre P. Massion
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Lung adenocarcinoma (LUAD) is the predominant type of lung cancer in the U.S. and exhibits a broad variety of behaviors ranging from indolent to aggressive. Identification of the biological determinants of LUAD behavior at early stages can i
Externí odkaz:
https://doaj.org/article/0aa600558c58426ca5beeb5b7def2354
Autor:
Rafael Paez, Michael N. Kammer, Aneri Balar, Dhairya A. Lakhani, Michael Knight, Dianna Rowe, David Xiao, Brent E. Heideman, Sanja L. Antic, Heidi Chen, Sheau-Chiann Chen, Tobias Peikert, Kim L. Sandler, Bennett A. Landman, Stephen A. Deppen, Eric L. Grogan, Fabien Maldonado
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract A deep learning model (LCP CNN) for the stratification of indeterminate pulmonary nodules (IPNs) demonstrated better discrimination than commonly used clinical prediction models. However, the LCP CNN score is based on a single timepoint that
Externí odkaz:
https://doaj.org/article/7b78666c04264aa586a2c11b09157b75
Autor:
Michael N. Kammer, PhD, Hidetoshi Mori, PhD, Dianna J. Rowe, BS, Sheau-Chiann Chen, PhD, Georgii Vasiukov, PhD, Thomas Atwater, MD, Maria Fernanda Senosain, PhD, Sanja Antic, MD, Yong Zou, MS, Heidi Chen, PhD, Tobias Peikert, MD, Steve Deppen, PhD, Eric L. Grogan, MD, Pierre P. Massion, MD, Steve Dubinett, MD, Marc Lenburg, PhD, Alexander Borowsky, MD, Fabien Maldonado, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 9, Pp 100504- (2023)
Introduction: Lung cancer is the deadliest cancer in the United States and worldwide, and lung adenocarcinoma (LUAD) is the most prevalent histologic subtype in the United States. LUAD exhibits a wide range of aggressiveness and risk of recurrence, b
Externí odkaz:
https://doaj.org/article/965e0718212541d0a561efc2131ac3f6
Autor:
Manisha Ray, Kazufumi Nagai, Yasuyuki Kihara, Amanda Kussrow, Michael N. Kammer, Aaron Frantz, Darryl J. Bornhop, Jerold Chun
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 8, Pp 1244-1251 (2020)
Native interactions between lysophospholipids (LPs) and their cognate LP receptors are difficult to measure because of lipophilicity and/or the adhesive properties of lipids, which contribute to high levels of nonspecific binding in cell membrane pre
Externí odkaz:
https://doaj.org/article/07f8a7465ce3454baabeb0ede8698fc2
Publikováno v:
ACS Omega, Vol 5, Iss 20, Pp 11308-11313 (2020)
Externí odkaz:
https://doaj.org/article/981a57b1d0a94dac84ab395f7f7f5ceb
Autor:
Hannah N. Marmor, Stephen A. Deppen, Valerie Welty, Michael N. Kammer, Caroline M. Godfrey, Khushbu Patel, Fabien Maldonado, Heidi Chen, Sandra L. Starnes, David O. Wilson, Ehab Billatos, Eric L. Grogan
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:329-336
Background:Indeterminate pulmonary nodules (IPN) are a diagnostic challenge in regions where pulmonary fungal disease and smoking prevalence are high. We aimed to determine the impact of a combined fungal and imaging biomarker approach compared with
Publikováno v:
ACS Omega. 7:31916-31923
CYFRA 21.1, a cytokeratin fragment of epithelial origin, has long been a valuable blood-based biomarker. As with most biomarkers, the clinical diagnostic value of CYFRA 21.1 is dependent on the quantitative performance of the assay. Looking toward tr
Publikováno v:
Chest. 162:265-268
Autor:
Rafael Paez, Michael N. Kammer, Nicole T. Tanner, Samira Shojaee, Brent E. Heideman, Tobias Peikert, Meridith L. Balbach, Wade T. Iams, Boting Ning, Marc E. Lenburg, Christopher Mallow, Lonny Yarmus, Kwun M. Fong, Stephen Deppen, Eric L. Grogan, Fabien Maldonado
Publikováno v:
Chest.
Autor:
Michael N. Kammer, Dianna J. Rowe, Stephen A. Deppen, Eric L. Grogan, Alexander M. Kaizer, Anna E. Barón, Fabien Maldonado
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background: Diagnostic prediction models are useful guides when considering lesions suspicious for cancer, as they provide a quantitative estimate of the probability that a lesion is malignant. However, the decision to intervene ultimately rests on p