Zobrazeno 1 - 10
of 1 545
pro vyhledávání: '"N, Fox"'
Publikováno v:
BJGP Open, Vol 8, Iss 2 (2024)
Background: Relational continuity of care (patients seeing the same GP) is associated with better outcomes for patients, but it has been declining in general practice in the UK. Aim: To understand what interventions have been tried to improve relatio
Externí odkaz:
https://doaj.org/article/821f13389c98407a953fdc2944c1a229
Autor:
Azariah K. Kaplelach, Stephanie N. Fox, Anna K. Cook, Justin A. Hall, Ryan S. Dannemiller, Karen L. Jaunarajs, Andrew E. Arrant
Publikováno v:
Neurobiology of Disease, Vol 188, Iss , Pp 106326- (2023)
Progranulin is a secreted pro-protein that has anti-inflammatory and neurotrophic effects and is necessary for maintaining lysosomal function. Mutations in progranulin (GRN) are a major cause of frontotemporal dementia. Most pathogenic GRN mutations
Externí odkaz:
https://doaj.org/article/52572181a12143e1a164172327fe3964
Autor:
S. N. Fox, L. J. McMeekin, C. H. Savage, K. L. Joyce, S. M. Boas, M. S. Simmons, C. B. Farmer, J. Ryan, L. Pereboeva, K. Becker, J. Auwerx, S. Sudarshan, J. Ma, A. Lee, R. C. Roberts, D. K. Crossman, A. Kralli, R. M. Cowell
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-19 (2022)
Abstract Many studies implicate mitochondrial dysfunction as a key contributor to cell loss in Parkinson disease (PD). Previous analyses of dopaminergic (DAergic) neurons from patients with Lewy-body pathology revealed a deficiency in nuclear-encoded
Externí odkaz:
https://doaj.org/article/ea2bd0f17cd2417ea87f86dbe8b0be2d
Publikováno v:
Biomimetics, Vol 7, Iss 4, p 157 (2022)
In the course of the development of the nervous system, neuronal cells extend (grow) axons, which navigate over distances of the order of many cell diameters to reach target dendrites from other neurons and establish neuronal circuits. Some of the ce
Externí odkaz:
https://doaj.org/article/08858432591948bbbaaf666aab2ff2c2
Publikováno v:
Socius, Vol 7 (2021)
Social inequality is a central topic of research in the social sciences. Decades of research have deepened our understanding of the characteristics and causes of social inequality. At the same time, social inequality has markedly increased during the
Externí odkaz:
https://doaj.org/article/d99b42f1366f4f428c7aef6c0797eea0
Autor:
Stephanie A. Schultz, Jeremy F. Strain, Adedamola Adedokun, Qing Wang, Oliver Preische, Jens Kuhle, Shaney Flores, Sarah Keefe, Aylin Dincer, Beau M. Ances, Sarah B. Berman, Adam M. Brickman, David M. Cash, Jasmeer Chhatwal, Carlos Cruchaga, Michael Ewers, Nick N. Fox, Bernardino Ghetti, Alison Goate, Neill R. Graff-Radford, Jason J. Hassenstab, Russ Hornbeck, Clifford Jack, Jr, Keith Johnson, Nelly Joseph-Mathurin, Celeste M. Karch, Robert A. Koeppe, Athene K.W. Lee, Johannes Levin, Colin Masters, Eric McDade, Richard J. Perrin, Christopher C. Rowe, Stephen Salloway, Andrew J. Saykin, Reisa Sperling, Yi Su, Victor L. Villemagne, Jonathan Vöglein, Michael Weiner, Chengjie Xiong, Anne M. Fagan, John C. Morris, Randall J. Bateman, Tammie L.S. Benzinger, Mathias Jucker, Brian A. Gordon
Publikováno v:
Neurobiology of Disease, Vol 142, Iss , Pp 104960- (2020)
Neurofilament light chain (NfL) is a protein that is selectively expressed in neurons. Increased levels of NfL measured in either cerebrospinal fluid or blood is thought to be a biomarker of neuronal damage in neurodegenerative diseases. However, the
Externí odkaz:
https://doaj.org/article/715a9dd1ef8d47e39b69d4c948b3a8f5
Autor:
Lucien Barnes, Douglas M. Heithoff, Scott P. Mahan, Gary N. Fox, Andrea Zambrano, Jane Choe, Lynn N. Fitzgibbons, Jamey D. Marth, Jeffrey C. Fried, H. Tom Soh, Michael J. Mahan
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 73-82 (2018)
Background: There is an urgent need for rapid, sensitive, and affordable diagnostics for microbial infections at the point-of-care. Although a number of innovative systems have been reported that transform mobile phones into potential diagnostic tool
Externí odkaz:
https://doaj.org/article/dc03a096f3b54706969e9747b2141ada
Autor:
L. Markelin, J. Suomalainen, R. A. Oliveira, N. Viljanen, R. Näsi, B. Scott, T. Theocharous, C. Greenwell, N. Fox, E. Honkavaara
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLII-1, Pp 283-288 (2018)
We study and analyse performance of a system for direct reflectance measurements from a drone. Key instruments of the system are upwards looking irradiance sensor and downwards looking imaging spectrometer. Requirement for both instruments is that th
Externí odkaz:
https://doaj.org/article/ef8de947f287432ab9594a9d3bb886dc
Autor:
Ashley N. Fox, Winter J. Smith, Katherine E. Kupiec, Stephanie J. Harding, Beth H. Resman-Targoff, Stephen B. Neely, Bryan P. White, Ryan E. Owens
Publikováno v:
Therapeutic Advances in Infectious Disease, Vol 6 (2019)
Background: Food and Drug Administration–approved daptomycin dosing uses actual body weight, despite limited dosing information for obese patients. Studies report alterations in daptomycin pharmacokinetics and creatine phosphokinase elevations asso
Externí odkaz:
https://doaj.org/article/f08129143f0d460d808a27068044776a
Autor:
Brian Hitsman, George D. Papandonatos, Jacqueline K. Gollan, Mark D. Huffman, Raymond Niaura, David C. Mohr, Anna K. Veluz‐Wilkins, Su Fen Lubitz, Anita Hole, Frank T. Leone, Sadiya S. Khan, Erica N. Fox, Anna‐Marika Bauer, E. Paul Wileyto, Joseph Bastian, Robert A. Schnoll
Publikováno v:
Addiction.