Zobrazeno 1 - 10
of 100
pro vyhledávání: '"N, Doyen"'
Publikováno v:
Health Services Research.
Introduction Since 2002, long-term absenteeism in Belgium has steadily increased each year. In 2016, 5.13% of the Belgian working population was on sickness absence for >1 month. In Belgium, sickness-absence benefits are paid by the employer in the f
Publikováno v:
Europe PubMed Central
We analyzed the progeny of individual multipotent hemopoietic cells, derived from the para-aortic splanchopleura, the earliest identified source of lymphocyte precursors in pre-liver mouse embryos. Single precursors were expanded in an in vitro cultu
Publikováno v:
The Journal of Immunology. 158:715-723
N region diversity in Ag receptors is a developmentally regulated process in B and T cells that correlates with the differential expression of terminal deoxynucleotidyl transferase (TdT). Absent in fetal and newborn mice, TdT expression is restricted
Publikováno v:
Journal of molecular biology. 292(2)
The terminal deoxynucleotidyl transferase gene (TdT) is expressed in mice only in early B and T lymphoid precursors a few days after birth. Transactivating factors have been shown to contribute to the lymphoid specific expression of TdT, but they do
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(4)
Nontemplated (N) nucleotide additions contribute significantly to the junctional diversity of all Ag receptor chains in adult mice except Ig light (L) chains, primarily because terminal deoxynucleotidyl transferase (TdT) expression is turned off at t
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(12)
During neonatal life, Ig diversity is limited in many respects. The absence of terminal deoxynucleotidyl transferase (TdT) expression with the consequent lack of nontemplated addition during the neonatal period, coupled with the predominant usage of
Publikováno v:
Journal of molecular biology. 281(5)
The hallmark of Fanconi anemia (FA), a rare inherited cancer prone disorder, is a high level of chromosome breakage, spontaneous and induced by cross-linking agents. The increased genomic instability of FA is reflected at the gene level by an overpro
Autor:
D. Papadpoulo, F. Rougeon, N. Doyen, J.C. Andrau, S. Kallenbach, Ethel Moustacchi, Agnès Laquerbe
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 360:207
Publikováno v:
Journal of Biological Chemistry. 257:2770-2774
The antigenic structure of human albumin was investigated in order to establish whether or not there was any similarity between its antigenic sites. Using immunoadsorbent columns prepared with cyanogen bromide fragments of human serum albumin, antibo
Autor:
N Doyen, C Lapresle
Publikováno v:
Biochemical Journal. 177:251-254
When human albumin was treated with CNBr, a fragment designated D was obtained and attributed to the absence from some of the albumin molecules of methionine at position 123 [Lapresle & Doyen (1975) Biochem. J. 151, 637-643]. The present study shows