Zobrazeno 1 - 10
of 689
pro vyhledávání: '"N, De Luca"'
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 855 (2024)
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally and is primarily caused by cigarette smoking (CS). Neurocognitive comorbidities such as anxiety and cognitive impairments are common among people with COPD. CS-
Externí odkaz:
https://doaj.org/article/3aaef7fe3a224563bb44e5286f93a508
Autor:
Simone N. De Luca, Kurt Brassington, Stanley M. H. Chan, Aleksandar Dobric, Kevin Mou, Huei Jiunn Seow, Ross Vlahos
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-16 (2022)
Abstract Background Cigarette smoking (CS) is the leading cause of chronic obstructive pulmonary disease (COPD). The “spill-over” of pulmonary inflammation into the systemic circulation may damage the brain, leading to cognitive dysfunction. Cess
Externí odkaz:
https://doaj.org/article/3e7a027d1718470fbcfc5197f3e05db8
Autor:
Aleksandar Dobric, Simone N. De Luca, Huei Jiunn Seow, Hao Wang, Kurt Brassington, Stanley M. H. Chan, Kevin Mou, Jonathan Erlich, Stella Liong, Stavros Selemidis, Sarah J. Spencer, Steven Bozinovski, Ross Vlahos
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Background and ObjectiveNeurocognitive dysfunction is present in up to ∼61% of people with chronic obstructive pulmonary disease (COPD), with symptoms including learning and memory deficiencies, negatively impacting the quality of life of these ind
Externí odkaz:
https://doaj.org/article/a877ab5c1eb34adcb041374018a5eb00
Autor:
Simone N. De Luca, Alita Soch, Luba Sominsky, Thai-Xinh Nguyen, Abdulhameed Bosakhar, Sarah J. Spencer
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Microglia play a key role in neuronal circuit and synaptic maturation in the developing brain. In the healthy adult, however, their role is less clear: microglial hyperactivation in adults can be detrimental to memory due to exces
Externí odkaz:
https://doaj.org/article/915d67117c6c4bedbe4c3e67f72f056c
Autor:
Kevin Mou, Stanley M. H. Chan, Kurt Brassington, Aleksandar Dobric, Simone N. De Luca, Huei Jiunn Seow, Stavros Selemidis, Steven Bozinovski, Ross Vlahos
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Limb muscle dysfunction is a hallmark of Chronic Obstructive Pulmonary Disease (COPD) which is further worsened following a viral-induced acute exacerbation of COPD (AECOPD). An amplified airway inflammation underlies the aggravated respiratory sympt
Externí odkaz:
https://doaj.org/article/7be818b25e384a6582b627fb213a38cc
Autor:
Simone N. De Luca, Stanley M.H. Chan, Aleksandar Dobric, Hao Wang, Huei Jiunn Seow, Kurt Brassington, Kevin Mou, Rana Alateeq, Alina Akhtar, Steven Bozinovski, Ross Vlahos
Publikováno v:
Brain, Behavior, and Immunity. 109:292-307
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d67cee50c861c15566121617315e3e28
https://doi.org/10.1016/j.bbi.2023.02.005
https://doi.org/10.1016/j.bbi.2023.02.005
Publikováno v:
Purinergic Signalling.
The activation of P2X7 is a well-known stimulus for the NLRP3-caspase 1 inflammasome and subsequent rapid IL-1β secretion from monocytes and macrophages. Here we show that positive allosteric modulators of P2X7, ginsenosides, can enhance the release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a06cc3d170d21db0a2e9e82c69e5b4
https://doi.org/10.1007/s11302-023-09935-0
https://doi.org/10.1007/s11302-023-09935-0
Akademický článek
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Akademický článek
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Autor:
Stanley M. H. Chan, Kurt Brassington, Suleman Abdullah Almerdasi, Aleksandar Dobric, Simone N. De Luca, Madison Coward‐Smith, Hao Wang, Kevin Mou, Alina Akhtar, Rana Abdullah Alateeq, Wei Wang, Huei Jiunn Seow, Stavros Selemidis, Steven Bozinovski, Ross Vlahos
Publikováno v:
British Journal of Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d27eb14315ca4d7523a0a8d7b0b3fb14
https://doi.org/10.1111/bph.16068
https://doi.org/10.1111/bph.16068