Zobrazeno 1 - 10
of 121
pro vyhledávání: '"N, Campion"'
Autor:
Lindsey N. Campion, Alan Meijia Maza, Rachita Yadav, Ellen B. Penney, Micaela G. Murcar, Kevin Correia, Tammy Gillis, Cara Fernandez-Cerado, M. Salvie Velasco-Andrada, G. Paul Legarda, Niecy G. Ganza-Bautista, J. Benedict B. Lagarde, Patrick J. Acuña, Trisha Multhaupt-Buell, Gabrielle Aldykiewicz, Melanie L. Supnet, Jan K. De Guzman, Criscely Go, Nutan Sharma, Edwin L. Munoz, Mark C. Ang, Cid Czarina E. Diesta, D. Cristopher Bragg, Laurie J. Ozelius, Vanessa C. Wheeler
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract X-linked dystonia-parkinsonism (XDP) is a progressive adult-onset neurodegenerative disorder caused by insertion of a SINE-VNTR-Alu (SVA) retrotransposon in the TAF1 gene. The SVA retrotransposon contains a CCCTCT hexameric repeat tract of v
Externí odkaz:
https://doaj.org/article/baac467a9e3b4fe08c219fe871aff898
Autor:
Lindsey N. Campion, Alan Mejia Maza, Rachita Yadav, Ellen B. Penney, Micaela G. Murcar, Kevin Correia, Tammy Gillis, Cara Fernandez-Cerado, M. Salvie Velasco-Andrada, G. Paul Legarda, Niecy G. Ganza-Bautista, J. Benedict B. Lagarde, Patrick J. Acuña, Trisha Multhaupt-Buell, Gabrielle Aldykiewicz, Melanie L. Supnet, Jan K. De Guzman, Criscely Go, Nutan Sharma, Edwin L. Munoz, Mark C. Ang, Cid Czarina E. Diesta, D. Cristopher Bragg, Laurie J. Ozelius, Vanessa C. Wheeler
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/ef4d8509314d40a785b9044ba45ef7f7
Autor:
Michelle R. Garnsey, Aaron C. Smith, Jana Polivkova, Autumn L. Arons, Guoyun Bai, Caroline Blakemore, Markus Boehm, Leanne M. Buzon, Sarah N. Campion, Matthew Cerny, Shiao-Chi Chang, Karen Coffman, Kathleen A. Farley, Kari R. Fonseca, Kristen K. Ford, Jeonifer Garren, Jimmy X. Kong, Martin R. M. Koos, Daniel W. Kung, Yajing Lian, Monica M. Li, Qifang Li, Luis A. Martinez-Alsina, Rebecca O’Connor, Kevin Ogilvie, Kiyoyuki Omoto, Brian Raymer, Matthew R. Reese, Tim Ryder, Lacey Samp, Kimberly A. Stevens, Daniel W. Widlicka, Qingyi Yang, Kaicheng Zhu, Jean-Philippe Fortin, Matthew F. Sammons
Publikováno v:
Journal of Medicinal Chemistry. 66:3195-3211
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ba50d658838cab5c2164045c8015f51
https://doi.org/10.1021/acs.jmedchem.2c02012
https://doi.org/10.1021/acs.jmedchem.2c02012
Autor:
Sarah N. Campion, William S. Nowland, Kathryn Gropp, Chang‐Ning Liu, Hayley N. Ritenour, Jameel Syed, Natasha Catlin, Christine M. Stethem, Timothy M. Coskran, Gregg D. Cappon
Publikováno v:
Birth Defects Research. 114:863-872
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e36fa20723992a64412fab44ef95dfc4
https://doi.org/10.1002/bdr2.2071
https://doi.org/10.1002/bdr2.2071
Autor:
Natasha R Catlin, Christopher J Bowman, Sarah N Campion, Elise M Lewis, William S Nowland, Christine Stethem, Gregg D Cappon
Publikováno v:
Toxicological Sciences. 189:225-236
Ervogastat (PF-06865571) is a small molecule diacylglycerol acyltransferase 2 (DGAT2) inhibitor being developed for the oral treatment of nonalcoholic steatohepatitis (NASH) with liver fibrosis. DGAT2 is a key enzyme in triglyceride synthesis in tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8406685f49264eb55b560fab52e2d7d6
https://doi.org/10.1093/toxsci/kfac077
https://doi.org/10.1093/toxsci/kfac077
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Sarah N. Campion, Christopher J. Bowman, Antje Fuchs, David Karanian, Payal Rana, Gregg D. Cappon
Publikováno v:
Birth defects researchREFERENCES.
Achondroplasia is an autosomal disorder caused by point mutation in the gene encoding fibroblast growth factor receptor 3 (FGFR3) and resulting in gain of function. Recifercept is a potential disease modifying treatment for achondroplasia and functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3261062f97b1f60d4f7ae6a010cfedae
https://pubmed.ncbi.nlm.nih.gov/36367445
https://pubmed.ncbi.nlm.nih.gov/36367445
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
William S. Nowland, Steven W. Kumpf, Trenton T. Ross, Christopher J. Bowman, Gregg D. Cappon, Donald S Stedman, Scott D Davenport, William P. Esler, Christine Stethem, Natasha R. Catlin, Elise M. Lewis, Sarah N. Campion
Publikováno v:
Toxicological Sciences. 179:183-194
Acetyl-CoA carboxylase (ACC) is an enzyme within the de novo lipogenesis (DNL) pathway and plays a role in regulating lipid metabolism. Pharmacologic ACC inhibition has been an area of interest for multiple potential indications including oncology, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6d9eb6a77626c055c46264ceba500b
https://doi.org/10.1093/toxsci/kfaa169
https://doi.org/10.1093/toxsci/kfaa169
Autor:
N R, Catlin, C J, Bowman, S N, Campion, J R, Cheung, W S, Nowland, J G, Sathish, C M, Stethem, L, Updyke, G D, Cappon
Publikováno v:
Reproductive Toxicology (Elmsford, N.y.)
Nirmatrelvir (PF-07321332; NMV) the antiviral component of PAXLOVID™ is a potent and selective inhibitor of the SARS-CoV-2 main protease (Mpro), which plays a critical role in viral replication. PAXLOVID, comprised of nirmatrelvir and ritonavir (us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8cf277e0aa37bda945307af72fac89c
https://pubmed.ncbi.nlm.nih.gov/35101563
https://pubmed.ncbi.nlm.nih.gov/35101563