Zobrazeno 1 - 10
of 41
pro vyhledávání: '"N, Cahir"'
Autor:
Nigel P. Groome, N. Cahir, Tanneale Stephenson, Peter G. Stanton, Enid Pruysers, David Robertson, Prema P Thirunavukarasu, Anna Tsigos
Publikováno v:
Molecular and Cellular Endocrinology. 180:79-86
Inhibin immunoassays with a sufficiently broad specificity to detect all alpha subunit-containing forms are of value in detecting and monitoring various ovarian cancers. Assays to date with this specificity are not readily amenable to wide diagnostic
Autor:
David Robertson, Nigel P. Groome, T. Eldar-Geva, David L. Healy, Vivien MacLachlan, N. Cahir, M. P. Gabbe
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:607-613
The aim of this study was to investigate the relationship of serum inhibin A and inhibin B to ovarian follicular development in women undergoing pituitary down-regulation and ovarian stimulation with a fixed daily dose of recombinant human FSH in an
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:889-896
In a previous study (see Ref.7), the molecular weight distribution of inhibin activity in fractionated human follicular fluid (hFF) and human male and female plasma/serum was determined by in vitro bioassay using ovine pituitary cells in culture and
Autor:
L. Clarke, J. Jacobsen, H. G. Burger, David Robertson, D. M. De Kretser, Paul G. Farnworth, N. Cahir
Publikováno v:
Journal of Endocrinology. 124:417-423
The mode of action of a recently isolated gonadal protein, termed FSH-suppressing protein (FSP) or follistatin, on basal and gonadotrophin-releasing hormone (GnRH)-stimulated release of FSH and LH and on pituitary cell content of FSH and LH was exami
Publikováno v:
Clinical chemistry. 45(5)
The reproductive hormone inhibin has been used as a diagnostic marker of ovarian mucinous and granulosa cell cancers. The aims of this study were to develop a new inhibin immunofluorometric assay (alphaC IFMA) to replace an inhibin RIA as a diagnosti
Autor:
Lorraine Dennerstein, Emma Dudley, David Robertson, Henry G. Burger, N. Cahir, Nigel P. Groome, Adèle C. Green
Publikováno v:
Clinical endocrinology. 48(6)
BACKGROUND Serum FSH levels rise with increasing age in normal women, particularly as they enter the menopausal transition and progress to the postmenopausal state. The contributions of decreasing levels of inhibin-A (INH-A) and inhibin-B (INH-B) to
Publikováno v:
The Journal of clinical endocrinology and metabolism. 82(3)
In a previous study (see Ref.7), the molecular weight distribution of inhibin activity in fractionated human follicular fluid (hFF) and human male and female plasma/serum was determined by in vitro bioassay using ovine pituitary cells in culture and
Autor:
N. Cahir, P. Mamers, Tom Jobling, Henry G. Burger, David L. Healy, Nigel P. Groome, David Robertson
Publikováno v:
Clinical endocrinology. 44(4)
BACKGROUND AND OBJECTIVE We have previously reported elevated serum immunoreactive inhibin (INH) levels in patients with ovarian malignancies, particularly granulosa cell and mucinous tumours. The present study was designed to compare INH measurement
Autor:
E Poncelet, David Robertson, NP Groome, J Sullivan, JP Mather, Teresa K. Woodruff, P Franchimont, Henry G. Burger, N. Cahir
Publikováno v:
The Journal of clinical endocrinology and metabolism. 81(2)
A number of immunoassay methods have been developed recently to detect specifically the bioactive alpha-beta A subunit inhibin dimer (inhibin A) in human plasma. However, the specificity of these assays in terms of their ability to detect the range o
Publikováno v:
The Journal of endocrinology. 144(2)
In order to identify the molecular weight forms of bioactive and immunoactive inhibin in human plasma, plasma/serum was sequentially fractionated by immunoaffinity chromatography (using immobilised inhibin α subunit antiserum), reversed phase HPLC a