Zobrazeno 1 - 10
of 35
pro vyhledávání: '"N, Buzzelli"'
Autor:
Jae Hong Im, Jon N. Buzzelli, Keaton Jones, Fanny Franchini, Alex Gordon-Weeks, Bostjan Markelc, Jianzhou Chen, Jin Kim, Yunhong Cao, Ruth J. Muschel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Macrophages contribute to tumour progression and response to therapy. Here, the authors show that absence of FGF2 in the tumour microenvironment reduces tumour growth and enhances the anti-tumour immune response by altering macrophage polarization. A
Externí odkaz:
https://doaj.org/article/aac2c94a42384be185bf6c4fce5f6dff
Publikováno v:
Stem Cell Research, Vol 27, Iss , Pp 109-120 (2018)
Background: Colorectal cancer (CRC) liver metastasis is highly unfavorable for patient outcome and is a leading cause of cancer-related death. Pre-clinical research of CRC liver metastasis predominately utilizes CRC cell lines grown in tissue culture
Externí odkaz:
https://doaj.org/article/c5c6ee3165a140de940bb8bc4c445a43
Autor:
Chau P. Tran, Michelle Scurr, Louise O’Connor, Jon N. Buzzelli, Garrett Z. Ng, Sharleen Chung Nien Chin, Lincon A. Stamp, Toshinari Minamoto, Andrew S. Giraud, Louise M. Judd, Philip Sutton, Trevelyan R. Menheniott
Publikováno v:
Oncotarget. 13:785-799
Interleukin-33 (IL-33) is an IL-1 family cytokine known to promote T-helper (Th) type 2 immune responses that are often deregulated in gastric cancer (GC). IL-33 is overexpressed in human gastric tumours suggesting a role in driving GC progression al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca6385c74001496010f6e5f430f42e9
https://doi.org/10.18632/oncotarget.28238
https://doi.org/10.18632/oncotarget.28238
Autor:
Jon N. Buzzelli, Heather V. Chalinor, Daniel I. Pavlic, Philip Sutton, Trevelyan R. Menheniott, Andrew S. Giraud, Louise M. Judd
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 2, Pp 203-221.e3 (2015)
Background & Aims: Interleukin (IL)33 is a recently described alarmin that is highly expressed in the gastric mucosa and potently activates Th2 immunity. It may play a pivotal role during Helicobacter pylori infection. Here, we delineate the role of
Externí odkaz:
https://doaj.org/article/fe5f543641b74220a8c56ac1013b6d5c
Akademický článek
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Autor:
Louise M. Judd, Sharleen Chung Nien Chin, Garrett Z. Ng, Jon N. Buzzelli, Philip Sutton, Hiroko Oshima, Michelle Scurr, Louise O'Connor, Angelique Catubig, Trevelyan R. Menheniott, Masanobu Oshima, Andrew S. Giraud
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 316:G251-G262
Expression of the cytokine IL-11 is elevated in human Helicobacter pylori infection and progressively increases with worsening gastric pathology. Additionally, IL-11 is required for tumor development in STAT3-dependent murine models of gastric cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d73e9fbc0780d1250064861c93c653
https://doi.org/10.1152/ajpgi.00304.2018
https://doi.org/10.1152/ajpgi.00304.2018
Publikováno v:
Stem Cell Research, Vol 27, Iss, Pp 109-120 (2018)
Stem Cell Research
Stem Cell Research
Background Colorectal cancer (CRC) liver metastasis is highly unfavorable for patient outcome and is a leading cause of cancer-related death. Pre-clinical research of CRC liver metastasis predominately utilizes CRC cell lines grown in tissue culture.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2d4e775deb5e27e61efd61b98829ed
https://doi.org/10.1016/j.scr.2018.01.016
https://doi.org/10.1016/j.scr.2018.01.016
Autor:
Emmanouil Fokas, Su Yin Lim, Keaton Jones, Jon N. Buzzelli, Ruth J. Muschel, Arseniy E. Yuzhalin, Bostjan Markelc, Yunhong Cao, Sean Smart, Alex Gordon-Weeks, K. Jin Kim
Publikováno v:
Hepatology. 65:1920-1935
Hepatic metastases are amenable to ablation; however, many patients are not suitable candidates for such therapy and recurrence is common. The tumor microenvironment is known to be essential for metastatic growth, yet identification of plausible targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7eb09c3a23cb139591d8adfb3c75a5
https://doi.org/10.1002/hep.29088
https://doi.org/10.1002/hep.29088
Autor:
Anderson J. Ryan, Cameron Brown, Yanyan Jiang, Maria Chatzifrangkeskou, Iolanda Vendrell, Eric O'Neill, Daniela Pankova, Jon N. Buzzelli
Publikováno v:
The EMBO Journal
Lung cancer remains the leading cause of cancer‐related death due to poor treatment responses and resistance arising from tumour heterogeneity. Here, we show that adverse prognosis associated with epigenetic silencing of the tumour suppressor RASSF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95b0212c13e42f50272730fb4285a89
https://doi.org/10.15252/embj.2018100532
https://doi.org/10.15252/embj.2018100532
Hippo Pathway Deregulation Drives Tissue Stiffness and Cancer Stem-like Cells in Lung Adenocarcinoma
Autor:
Cameron Brown, Daniela Pankova, Anderson J. Ryan, Iolanda Vendrell, Jon N. Buzzelli, Eric O'Neill, Yanyan Jiang
Lung cancer remains the leading cause of cancer-related death due to poor treatment responses arising from tumor heterogeneity and epigenetic aberrations. Here we show that adverse prognosis associated with epigenetically silenced tumour suppressor R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b118677b30678e8d6303abe95eeb6b9c
