Zobrazeno 1 - 10
of 45
pro vyhledávání: '"N, Brosius"'
Autor:
Graham D. Cochrane, Shima D. Anwar, Alice N. Weaver, Stephanie N. Brosius, Catherine H. Poholek, Heather Allen, Randy L. Seay, Robin G. Lorenz, Gregory A. Payne, William M. Geisler
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Abstract Introduction: Most students in MD-PhD programs take a leave of absence from medical school to complete PhD training, which promotes a natural loss of clinical skills and knowledge and could negatively impact a student’s long-term clinical
Externí odkaz:
https://doaj.org/article/f3f96e1b210e4f409549f4fb0b9419e8
Autor:
Shannon M. Weber, Nicole M. Brossier, Amanda Prechtl, Stephen Barnes, Landon S. Wilson, Stephanie N. Brosius, Jody Fromm Longo, Steven L. Carroll
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-21 (2021)
Abstract Background Loss of the Ras GTPase-activating protein neurofibromin promotes nervous system tumor pathogenesis in patients with neurofibromatosis type 1 (NF1). Neurofibromin loss potentially hyperactivates classic Ras (H-Ras, N-Ras, K-Ras), M
Externí odkaz:
https://doaj.org/article/b179198ca90645669df1b83a5b802b53
Autor:
Jody Fromm Longo, Stephanie N. Brosius, Iya Znoyko, Victoria A. Alers, Dorea P. Jenkins, Robert C. Wilson, Andrew J. Carroll, Daynna J. Wolff, Kevin A. Roth, Steven L. Carroll
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive Schwann cell-derived neoplasms that occur sporadically or in patients with neurofibromatosis type 1 (NF1). Preclinical research on sporadic MPNSTs has been limited as few cell
Externí odkaz:
https://doaj.org/article/f5187e91b33a4aedba5946cbbbfb1198
Autor:
Jody Fromm Longo, Stephanie N. Brosius, Laurel Black, Stuart H. Worley, Robert C. Wilson, Kevin A. Roth, Steven L. Carroll
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background We have found that erbB receptor tyrosine kinases drive Ras hyperactivation and growth in NF1-null malignant peripheral nerve sheath tumors (MPNSTs). However, MPNSTs variably express multiple erbB receptors with distinct functiona
Externí odkaz:
https://doaj.org/article/52d822e206d34315a428c088ee07c624
Autor:
Kairong Li, Ashley N. Turner, Min Chen, Stephanie N. Brosius, Trenton R. Schoeb, Ludwine M. Messiaen, David M. Bedwell, Kurt R. Zinn, Corina Anastasaki, David H. Gutmann, Bruce R. Korf, Robert A. Kesterson
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 7, Pp 759-767 (2016)
Neurofibromatosis type 1 (NF1) is a common genetic disorder characterized by the occurrence of nerve sheath tumors and considerable clinical heterogeneity. Some translational studies have been limited by the lack of animal models available for assess
Externí odkaz:
https://doaj.org/article/0316d1cb159646e299039a5e2abac96f
Autor:
Stephanie N. Brosius, Landon Wilson, Nicole M. Brossier, Steven L. Carroll, Jody Fromm Longo, Shannon M. Weber, Stephen Barnes, Amanda Prechtl
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-21 (2021)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background Loss of the Ras GTPase-activating protein neurofibromin promotes nervous system tumor pathogenesis in patients with neurofibromatosis type 1 (NF1). Neurofibromin loss potentially hyperactivates classic Ras (H-Ras, N-Ras, K-Ras), M-Ras, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9502ab4d33865d3935e0cccecd460cba
https://doaj.org/article/b179198ca90645669df1b83a5b802b53
https://doaj.org/article/b179198ca90645669df1b83a5b802b53
Publikováno v:
Neurology
Baylisascaris procyonis, or raccoon round worm, is a rare cause of eosinophilic meningoencephalitis with historically poor clinical outcomes. Symptoms of neural larval migrans begin approximately 2-4 weeks after ingestion with fatigue, nausea, fever,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a9858ed15a162eab003ef38d215480
https://europepmc.org/articles/PMC9651468/
https://europepmc.org/articles/PMC9651468/
Publikováno v:
Neurology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cccfdbfb3ce4595ab2fe754cc6c0bfac
https://doi.org/10.1212/wnl.0000000000201138
https://doi.org/10.1212/wnl.0000000000201138
Akademický článek
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Publikováno v:
J Vis Exp
The development of new drugs that precisely target key proteins in human cancers is fundamentally altering cancer therapeutics. However, before these drugs can be used, their target proteins must be validated as therapeutic targets in specific cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::511663fb5639a30fbcbccbf6a0b96ee7
https://pubmed.ncbi.nlm.nih.gov/34515675
https://pubmed.ncbi.nlm.nih.gov/34515675