Zobrazeno 1 - 10
of 62
pro vyhledávání: '"N, Binz"'
Autor:
Ilva D. Rupenthal, Colin R. Green, Odunayo O Mugisho, N. Binz, Monica L. Acosta, Jie Zhang, Elizabeth Rakoczy
Publikováno v:
International Journal of Molecular Sciences; Volume 18; Issue 12; Pages: 2567
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2567 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2567 (2017)
International Journal of Molecular Sciences
Diabetic retinopathy (DR) develops due to hyperglycemia and inflammation-induced vascular disruptions in the retina with connexin43 expression patterns in the disease still debated. Here, the effects of hyperglycemia and inflammation on connexin43 ex
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0160442 (2016)
PLoS ONE, Vol 11, Iss 8, p e0160442 (2016)
Purpose The endothelins are a family of three highly conserved and homologous vasoactive peptides that are expressed across all organ systems. Endothelin (Edn) dysregulation has been implicated in a number of pathophysiologies, including diabetes and
Autor:
Paul G. McMenamin, N. Binz, Eric Pearlman, Yan Sun, Mariapia A. Degli-Esposti, Samuel McLenachan, John V. Forrester, Holly R Chinnery
Publikováno v:
The American Journal of Pathology. 180:209-220
During bacterial and viral infections, unmethylated CpG-DNA released by proliferating and dying microbes is recognized by toll-like receptor (TLR) 9 in host cells, initiating innate immune responses. Many corneal infections occur secondary to epithel
Autor:
Chooi-May Lai, N. Binz, Diego Guidolin, Sarah A. Dunlop, Yvonne K. Y. Lai, Weiyong Shen, Piroska E. Rakoczy, Domenico Ribatti, J. Eade, Caroline E. Graham
Publikováno v:
Diabetologia. 49:1690-1701
Vascular endothelial growth factor (VEGF) plays a pivotal role in the pathogenesis of diabetic retinopathy. We investigated whether transgenic mice with moderate VEGF expression in photoreceptors (trVEGF029) developed changes similar to diabetic reti
Autor:
Nigel G. Laing, Albrecht Gruhler, Hanns Lochmüller, Bettina Mendel, Rolf Stucka, Michaela Jaksch, Kristen J. Nowak, Christian Thirion, N. Binz
Publikováno v:
European Journal of Biochemistry. 268:3473-3482
Cofilins are actin binding proteins and regulate actin assembly in vivo. Numerous cofilin homologues have been characterized in various organisms including mammals. In mice, a ubiquitously expressed cofilin (CFL1) and a skeletal muscle specific cofil
Publikováno v:
Investigative ophthalmologyvisual science. 53(3)
PURPOSE The distribution, density, and phenotype of hyalocytes or vitreous macrophages in mouse eyes was examined during normal aging and in models of background diabetic retinopathy, retinal vascular proliferation, and exposure to TLR4 and TLR9 liga
Autor:
Nermina N. Vagaja, N. Binz, Ireni S. Ali Rahman, Chooi-May Lai, Marisa de Pinho, Elizabeth Rakoczy, Cai-Rui Li
Publikováno v:
The American journal of pathology. 177(5)
One of the limitations of research into diabetic retinopathy is the lack of suitable animal models. To study how the two important factors--hyperglycemia and vascular endothelial growth factor--interact in diabetic retinopathy, the Akimba mouse (Ins2
Autor:
Lyn Beazley, Sarah A. Dunlop, Yvonne K. Y. Lai, Weiyong Shen, N. Binz, P. Elizabeth Rakoczy, Chooi-May Lai
Publikováno v:
Retinal Degenerative Diseases ISBN: 9780387284644
Retinal neovascularization is a feature shared by many disease processes including diabetic retinopathy, retinopathy of prematurity, branch retinal vein occlusion and central retinal vein occlusion, which are collectively referred to as ischemic reti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59091146748895a38d9cbb9b7f942984
https://doi.org/10.1007/0-387-32442-9_28
https://doi.org/10.1007/0-387-32442-9_28
Publikováno v:
Retinal Degenerative Diseases ISBN: 9780387284644
Diabetic retinopathy is a severe complication of diabetes leading to some degree of vision impairment in long-term diabetes sufferers. Currently, the most successful treatment available for diabetic retinopathy is laser photocoagulation, a therapy th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d0553c2c87933529af2a809664a38f1
https://doi.org/10.1007/0-387-32442-9_29
https://doi.org/10.1007/0-387-32442-9_29
Autor:
Chooi-May Lai, Yvonne K. Y. Lai, Terence P. Speed, Weiyong Shen, Caroline E. Graham, P. Elizabeth Rakoczy, Ken M. Simpson, N. Binz
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(2)
Microarray-based gene expression analysis demonstrated that laser photocoagulation (LPC) of mouse eyes had a long-term effect on the expression of genes functionally related to tissue repair, cell migration, proliferation, ion, protein and nucleic ac