Zobrazeno 1 - 10
of 164
pro vyhledávání: '"N, Appaji Rao"'
Autor:
N. Appaji Rao, A. Jagannadha Rao
Publikováno v:
Journal of Biosciences. 37:207-210
Autor:
P. Kaul, V. Prakash, S. Bisht, Handanahal S. Savithri, N. Appaji Rao, V. Rajaram, B.S. Bhavani, Mathur R. N. Murthy
Publikováno v:
FEBS Journal. 275:4606-4619
Serine hydroxymethyltransferase (SHMT) from Bacillus stearothermophilus (bsSHMT) is a pyridoxal 5'-phosphate-dependent enzyme that catalyses the conversion of l-serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. In addition,
Autor:
Mathur R. N. Murthy, N. Appaji Rao, Handanahal S. Savithri, P. Kaul, B.S. Bhavani, V. Prakash, V. Rajaram
Publikováno v:
FEBS Journal. 274:4148-4160
Serine hydroxymethyltransferase (SHMT) belongs to the alpha-family of pyridoxal 5'-phosphate-dependent enzymes and catalyzes the reversible conversion of L-Ser and etrahydrofolate to Gly and 5,10-methylene tetrahydrofolate. 5,10-Methylene tetrahydrof
Publikováno v:
Journal of Biosciences. 27:233-242
Serine hydroxymethyltransferase (SHMT), a pyridoxal-5' -phosphate (PLP) dependent enzyme catalyzes the interconversion of L-Ser and Gly using tetrahydrofolate as a substrate. The gene encoding for SHMT was amplified by PCR from genomic DNA of Bacillu
Autor:
N. Appaji Rao, G.S. Jagannatha Rao, Hosahalli Subramanya, Handanahal S. Savithri, Vishal Trivedi, Amrita Gupta, Venkatakrishna R. Jala, P. Saravanan
Publikováno v:
Journal of Biological Chemistry. 277:17161-17169
Serine hydroxymethyltransferase (SHMT), a member of the α-class of pyridoxal phosphate-dependent enzymes, catalyzes the reversible conversion of serine to glycine and tetrahydrofolate to 5,10-methylene tetrahydrofolate. We present here the crystal s
Publikováno v:
European Journal of Biochemistry. 267:5967-5976
The three-dimensional structures of human and rabbit liver cytosolic recombinant serine hydroxymethyltransferases (hcSHMT and rcSHMT) revealed that E75 and Y83 (numbering according to hcSHMT) are probable candidates for proton abstraction and Calpha-
Autor:
D. Kool, N. Appaji Rao, Alan H. Bittles, H. Venkatesha Murthy, Wei Wang, G Baskaran, Handanahal S. Savithri, E. Edkins
Publikováno v:
Clinical Genetics. 58:57-60
During the course of genome studies in a rural community in the South Indian state of Karnataka, DNA-based investigations and counselling for familial adenomatous polyposis (FAP) were requested via the community physician. The proposita died in 1940
Publikováno v:
European Journal of Biochemistry. 267:1441-1446
mutants had only 2‐3% catalytic activity. The side reactions like transamination and 5,6,7,8-tetrahydrofolate independent aldol cleavage were much more severely affected. They were able to form the external aldimine with glycine and serine but the
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1293:191-200
The non-oxidative decarboxylation of aromatic acids is a poorly understood reaction. The transformation of 2,3-dihydroxybenzoic acid to catechol in the fungal metabolism of indole is a prototype of such a reaction. 2,3-Dihydroxybenzoic acid decarboxy
Publikováno v:
Archives of Microbiology. 163:424-431