Zobrazeno 1 - 10
of 31
pro vyhledávání: '"N, Adey"'
Autor:
Steven J. Bright, Christopher Hübel, Katherine S. Young, Shannon Bristow, Alicia J. Peel, Christopher Rayner, Jessica Mundy, Alish B. Palmos, Kirstin L. Purves, Gursharan Kalsi, Cherie Armour, Ian R. Jones, Matthew Hotopf, Andrew M. McIntosh, Daniel J. Smith, James T. R. Walters, Henry C. Rogers, Katherine N. Thompson, Brett N. Adey, Dina Monssen, Saakshi Kakar, Chelsea M. Malouf, Colette Hirsch, Kiran Glen, Emily J. Kelly, David Veale, Thalia C. Eley, Gerome Breen, Molly R. Davies
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background The Genetic Links to Anxiety and Depression (GLAD) Study is a large cohort of individuals with lifetime anxiety and/or depression, designed to facilitate re-contact of participants for mental health research. At the start of the p
Externí odkaz:
https://doaj.org/article/0dd845c832e94fa4929585564fa821ee
Autor:
Brett N. Adey, Johnathan Cooper-Knock, Ahmad Al Khleifat, Isabella Fogh, Philip van Damme, Philippe Corcia, Philippe Couratier, Orla Hardiman, Russell McLaughlin, Marc Gotkine, Vivian Drory, Vincenzo Silani, Nicola Ticozzi, Jan H. Veldink, Leonard H. van den Berg, Mamede de Carvalho, Susana Pinto, Jesus S. Mora Pardina, Mónica Povedano Panades, Peter M. Andersen, Markus Weber, Nazli A. Başak, Christopher E. Shaw, Pamela J. Shaw, Karen E. Morrison, John E. Landers, Jonathan D. Glass, Patrick Vourc’h, Richard J. B. Dobson, Gerome Breen, Ammar Al-Chalabi, Ashley R. Jones, Alfredo Iacoangeli
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Introduction: Caveolin-1 and Caveolin-2 (CAV1 and CAV2) are proteins associated with intercellular neurotrophic signalling. There is converging evidence that CAV1 and CAV2 (CAV1/2) genes have a role in amyotrophic lateral sclerosis (ALS). Disease-ass
Externí odkaz:
https://doaj.org/article/c69bb290778f47b3905ab577dd0339df
Autor:
Ashley R. Jones, Alfredo Iacoangeli, Brett N. Adey, Harry Bowles, Aleksey Shatunov, Claire Troakes, Jeremy A. Garson, Adele L. McCormick, Ammar Al-Chalabi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract There is increasing evidence that endogenous retroviruses (ERVs) play a significant role in central nervous system diseases, including amyotrophic lateral sclerosis (ALS). Studies of ALS have consistently identified retroviral enzyme reverse
Externí odkaz:
https://doaj.org/article/fa585c9e6ffc49b992d0f81a36717fb6
Autor:
Ashley R. Jones, Alfredo Iacoangeli, Brett N. Adey, Harry Bowles, Aleksey Shatunov, Claire Troakes, Jeremy A. Garson, Adele L. McCormick, Ammar Al‑Chalabi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/5fe7f6d9038843a68f23e3c3e8844b7b
Autor:
Jessica Mundy, Christopher Hübel, Brett N. Adey, Helena L. Davies, Molly R. Davies, Jonathan R. I. Coleman, Matthew Hotopf, Gursharan Kalsi, Sang Hyuck Lee, Andrew M. McIntosh, Henry C. Rogers, Thalia C. Eley, Robin M. Murray, Evangelos Vassos, Gerome Breen
Publikováno v:
Mundy, J, Hübel, C, Adey, B N, Davies, H L, Davies, M R, Coleman, J R I, Hotopf, M, Kalsi, G, Lee, S H, McIntosh, A M, Rogers, H C, Eley, T C, Murray, R M, Vassos, E & Breen, G 2023, ' Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder ', American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics . https://doi.org/10.1002/ajmg.b.32938
Mundy, J, Hübel, C, Adey, B N, Davies, H L, Davies, M R, Coleman, J R I, Hotopf, M, Kalsi, G, Lee, S H, McIntosh, A M, Rogers, H C, Eley, T C, Murray, R M, Vassos, E & Breen, G 2023, ' Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder ', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . https://doi.org/10.1002/ajmg.b.32938
Mundy, J, Hübel, C, Adey, B N, Davies, H L, Davies, M R, Coleman, J R I, Hotopf, M, Kalsi, G, Lee, S H, McIntosh, A M, Rogers, H C, Eley, T C, Murray, R M, Vassos, E & Breen, G 2023, ' Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder ', American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics . https://doi.org/10.1002/ajmg.b.32938
Mundy, J, Hübel, C, Adey, B N, Davies, H L, Davies, M R, Coleman, J R I, Hotopf, M, Kalsi, G, Lee, S H, McIntosh, A M, Rogers, H C, Eley, T C, Murray, R M, Vassos, E & Breen, G 2023, ' Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder ', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . https://doi.org/10.1002/ajmg.b.32938
Mundy, J, Hübel, C, Adey, B N, Davies, H L, Davies, M R, Coleman, J R I, Hotopf, M, Kalsi, G, Lee, S H, McIntosh, A M, Rogers, H C, Eley, T C, Murray, R M, Vassos, E & Breen, G 2023, ' Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder ', American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics . https://doi.org/10.1002/ajmg.b.32938
The Mood Disorder Questionnaire (MDQ) is a common screening tool for bipolar disorder that assesses manic symptoms. Its utility for genetic studies of mania or bipolar traits has not been fully examined. We psychometrically compared the MDQ to self-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415c411233d622ef7b494907c26dafb8
https://pure.au.dk/portal/da/publications/genetic-examination-of-the-mood-disorder-questionnaire-and-its-relationship-with-bipolar-disorder(47ce0bc5-2e41-4bbe-89f4-fcde74c242ec).html
https://pure.au.dk/portal/da/publications/genetic-examination-of-the-mood-disorder-questionnaire-and-its-relationship-with-bipolar-disorder(47ce0bc5-2e41-4bbe-89f4-fcde74c242ec).html
Autor:
Molly R. Davies, Kiran Glen, Jessica Mundy, Abigail R. ter Kuile, Brett N. Adey, Chérie Armour, Elham Assary, Jonathan R.I. Coleman, Kimberley A. Goldsmith, Colette R. Hirsch, Matthew Hotopf, Christopher Hübel, Ian R. Jones, Gursharan Kalsi, Georgina Krebs, Andrew M. McIntosh, Geneviève Morneau-Vaillancourt, Alicia J. Peel, Kirstin L. Purves, Sang Hyuck Lee, Megan Skelton, Daniel J. Smith, David Veale, James T.R. Walters, Katherine S. Young, Johan Zvrskovec, Gerome Breen, Thalia C. Eley
Publikováno v:
Davies, M R, Glen, K, Mundy, J, Adey, B, Armour, C, Assary, E, Coleman, J, Goldsmith, K, Hirsch, C, Hotopf, M, Hübel, C, Jones, I, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A, Purves, K, Lee, S, Skelton, M, Smith, D J, Veale, D, Walters, J, Young, K, Källberg Zvrskovec, J, Breen, G & Grant, T E 2023, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders, vol. 323, pp. 280-291 . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Kuile, A R T, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2023, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders, vol. 323, pp. 280-291 . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Ter Kuile, A R, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2023, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders, vol. 323, pp. 280-291 . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Ter Kuile, A R, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2022, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders (JAD) . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Kuile, A R T, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2023, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders, vol. 323, pp. 280-291 . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Ter Kuile, A R, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2023, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders, vol. 323, pp. 280-291 . https://doi.org/10.1016/j.jad.2022.11.051
Davies, M R, Glen, K, Mundy, J, Ter Kuile, A R, Adey, B N, Armour, C, Assary, E, Coleman, J R I, Goldsmith, K A, Hirsch, C R, Hotopf, M, Hübel, C, Jones, I R, Kalsi, G, Krebs, G, McIntosh, A M, Morneau-Vaillancourt, G, Peel, A J, Purves, K L, Lee, S H, Skelton, M, Smith, D J, Veale, D, Walters, J T R, Young, K S, Zvrskovec, J, Breen, G & Eley, T C 2022, ' Factors associated with anxiety disorder comorbidity ', Journal of Affective Disorders (JAD) . https://doi.org/10.1016/j.jad.2022.11.051
BackgroundAnxiety and depressive disorders often co-occur and the order of their emergence may be associated with different clinical outcomes. However, minimal research has been conducted on anxiety-anxiety comorbidity. This study examined factors as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8507ef0fe5b84d714c262376017724af
https://kclpure.kcl.ac.uk/en/publications/6be14141-2856-46f3-8145-6b176d798a3b
https://kclpure.kcl.ac.uk/en/publications/6be14141-2856-46f3-8145-6b176d798a3b
Autor:
Dina Monssen, Helena L Davies, Shannon Bristow, Saakshi Kakar, Susannah C B Curzons, Molly R Davies, Zain Ahmad, John R Bradley, Steven Bright, Jonathan R I Coleman, Kiran Glen, Matthew Hotopf, Emily J Kelly, Abigail R Ter Kuile, Chelsea Mika Malouf, Gursharan Kalsi, Nathalie Kingston, Monika McAtarsney-Kovacs, Jessica Mundy, Alicia J Peel, Alish B Palmos, Henry C Rogers, Megan Skelton, Brett N Adey, Sang Hyuck Lee, Hope Virgo, Tom Quinn, Tom Price, Johan Zvrskovec, Thalia C Eley, Janet Treasure, Christopher Hübel, Gerome Breen
ObjectiveThe Eating Disorders Genetics Initiative United Kingdom (EDGI UK), part of the National Institute for Health and Care Research (NIHR) Mental Health BioResource, aims to deepen our understanding of the environmental and genetic aetiology of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f00a5ab01c32896d4b14a66d9606bef
https://doi.org/10.1101/2022.11.11.22282083
https://doi.org/10.1101/2022.11.11.22282083
Autor:
Brett N Adey, Johnathan Cooper-Knock, Ahmad Al Khleifat, Isabella Fogh, Philip van Damme, Philippe Corcia, Philippe Couratier, Orla Hardiman, Russell McLaughlin, Marc Gotkine, Vivian Drory, Vincenzo Silani, Nicola Ticozzi, Jan H. Veldink, Leonard H. van den Berg, Mamede de Carvalho, Susana Pinto, Jesus S. Mora Pardina, Monica Povedano, Peter M. Andersen, Markus Weber, Nazli A. Başak, Christopher E Shaw, Pamela J. Shaw, Karen E. Morrison, John E. Landers, Jonathan D. Glass, Patrick Vourc’h, Richard JB Dobson, Gerome Breen, Ammar Al-Chalabi, Ashley R Jones, Alfredo Iacoangeli
Publikováno v:
Adey, B N, Cooper-Knock, J, Al Khleifat, A, Fogh, I, van Damme, P, Corcia, P, Couratier, P, Hardiman, O, McLaughlin, R, Gotkine, M, Drory, V, Silani, V, Ticozzi, N, Veldink, J H, van den Berg, L H, de Carvalho, M, Pinto, S, Mora Pardina, J S, Povedano Panades, M, Andersen, P M, Weber, M, Başak, N A, Shaw, C E, Shaw, P J, Morrison, K E, Landers, J E, Glass, J D, Vourc'h, P, Dobson, R J B, Breen, G, Al-Chalabi, A, Jones, A R & Iacoangeli, A 2023, ' Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival ', Frontiers in Cellular Neuroscience, vol. 17, 1112405 . https://doi.org/10.3389/fncel.2023.1112405
Introduction: Caveolin-1 and Caveolin-2 (CAV1 and CAV2) are proteins associated with intercellular neurotrophic signalling. There is converging evidence that CAV1 and CAV2 (CAV1/2) genes have a role in amyotrophic lateral sclerosis (ALS). Disease-ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d08b66f9f07ede4c02972bec2478a29c
https://doi.org/10.1101/2022.11.04.22281798
https://doi.org/10.1101/2022.11.04.22281798
Autor:
A Martineau, Brett N. Adey, Gerome Breen, Papadia S, Maughan B, Alicia J. Peel, Jessica Mundy, Stirrups K, Matthew Richardson, Linger R, Ammar Al-Chalabi, Holt H, Melanie J. Davies, David Veale, Alish B. Palmos, Kirstin L. Purves, Y. Lin, Huebel C, Bristow S, Katherine N. Thompson, Evangelos Vassos, Ward C, Bradley J, Young Ks, Colette R. Hirsch, ter Kuile A, Gursharan Kalsi, Kingston N, Andrea Danese, Timothy R Nicholson, Georgina Krebs, Chaudhuri Kr, Sharon Stevelink, Thalia C. Eley, Bright S, Christopher Rayner, Pollak T, Chinnery P, Matthew Hotopf, Lee Yt, York K, Hegemann L, Dina Monssen, Moukhtarian T, Christine E. Parsons, Henry C. Rogers, Schmidt U
Publikováno v:
Young, K S, Purves, K L, Hübel, C, Davies, M R, Thompson, K N, Bristow, S, Krebs, G, Danese, A, Hirsch, C, Parsons, C E, Vassos, E, Adey, B N, Bright, S, Hegemann, L, Lee, Y T, Kalsi, G, Monssen, D, Mundy, J, Peel, A J, Rayner, C, Rogers, H C, Ter Kuile, A, Ward, C, York, K, Lin, Y, Palmos, A B, Schmidt, U, Veale, D, Nicholson, T R, Pollak, T A, Stevelink, S A M, Moukhtarian, T, Martineau, A R, Holt, H, Maughan, B, Al-Chalabi, A, Chaudhuri, K R, Richardson, M P, Bradley, J R, Chinnery, P F, Kingston, N, Papadia, S, Stirrups, K E, Linger, R, Hotopf, M, Eley, T C & Breen, G 2022, ' Depression, anxiety and PTSD symptoms before and during the COVID-19 pandemic in the UK ', Psychological Medicine, pp. 1-31 . https://doi.org/10.1017/S0033291722002501
Young, K S, Purves, K L, Hübel, C, Davies, M R, Thompson, K N, Bristow, S, Krebs, G, Danese, A, Hirsch, C, Parsons, C E, Vassos, E, Adey, B N, Bright, S, Hegemann, L, Lee, Y T, Kalsi, G, Monssen, D, Mundy, J, Peel, A J, Rayner, C, Rogers, H C, Ter Kuile, A, Ward, C, York, K, Lin, Y, Palmos, A B, Schmidt, U, Veale, D, Nicholson, T R, Pollak, T A, Stevelink, S A M, Moukhtarian, T, Martineau, A R, Holt, H, Maughan, B, Al-Chalabi, A, Chaudhuri, K R, Richardson, M P, Bradley, J R, Chinnery, P F, Kingston, N, Papadia, S, Stirrups, K E, Linger, R, Hotopf, M, Eley, T C & Breen, G 2022, ' Depression, anxiety and PTSD symptoms before and during the COVID-19 pandemic in the UK ', Psychological Medicine . https://doi.org/10.1017/S0033291722002501
Young, K S, Purves, K L, Hübel, C, Davies, M R, Thompson, K N, Bristow, S, Krebs, G, Danese, A, Hirsch, C, Parsons, C E, Vassos, E, Adey, B N, Bright, S, Hegemann, L, Lee, Y T, Kalsi, G, Monssen, D, Mundy, J, Peel, A J, Rayner, C, Rogers, H C, Ter Kuile, A, Ward, C, York, K, Lin, Y, Palmos, A B, Schmidt, U, Veale, D, Nicholson, T R, Pollak, T A, Stevelink, S A M, Moukhtarian, T, Martineau, A R, Holt, H, Maughan, B, Al-Chalabi, A, Chaudhuri, K R, Richardson, M P, Bradley, J R, Chinnery, P F, Kingston, N, Papadia, S, Stirrups, K E, Linger, R, Hotopf, M, Eley, T C & Breen, G 2022, ' Depression, anxiety and PTSD symptoms before and during the COVID-19 pandemic in the UK ', Psychological Medicine . https://doi.org/10.1017/S0033291722002501
Background The impact of the coronavirus disease 2019 (COVID-19) pandemic on mental health is still being unravelled. It is important to identify which individuals are at greatest risk of worsening symptoms. This study aimed to examine changes in dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa443453a7e17dd4e215357e81f24bca
https://pure.au.dk/portal/da/publications/depression-anxiety-and-ptsd-symptoms-before-and-during-the-covid19-pandemic-in-the-uk(cd8f1c7b-c55c-4536-bfc7-9d42d21749c4).html
https://pure.au.dk/portal/da/publications/depression-anxiety-and-ptsd-symptoms-before-and-during-the-covid19-pandemic-in-the-uk(cd8f1c7b-c55c-4536-bfc7-9d42d21749c4).html
Autor:
Jess Mundy, Brett N. Adey, Helena L. Davies, Molly R. Davies, Jonathan R.I. Coleman, Christopher Hubel, Gursharan Kalsi, Henry Rogers, Lee Sang Hyuck, GLAD collaborators: Cherie Armour, Matthew Hotopf, Ian R. Jones, Andrew McIntosh, Daniel J. Smith, James T.R. Walters, Thalia C. Eley, Robin M. Murray, Evangelos Vassos, Gerome Breen
Publikováno v:
European Neuropsychopharmacology. 63:e178-e179