Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Myung-Hee Chun"'
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1443 (2021)
Control strategy and quality by design (QbD) are widely used to develop pharmaceutical products and improve drug quality; however, studies on fixed-dose combination (FDC) bilayer tablets are limited. In this study, the bilayer tablet consisted of hig
Externí odkaz:
https://doaj.org/article/7694148c14714f46bb1380db600d1d20
Autor:
Dae Hwan Shin, Ju-Young Kim, Chun-Woong Park, Jinmann Chon, Ji Hyun Kang, Chang-Soo Han, Yun Seok Rhee, Myung Hee Chun, Dong-Wook Kim, Dong-Won Oh
Publikováno v:
Drug Development and Industrial Pharmacy. 47:685-693
As an active pharmaceutical ingredient, dapagliflozin propanediol monohydrate (D-PD) has been used in the solvated form consisting of dapagliflozin compounded with (S)-propylene glycol and monohydrate at a 1:1:1 ratio. However, dapagliflozin propaned
Publikováno v:
Pharmaceutics
Volume 13
Issue 1
Pharmaceutics, Vol 13, Iss 80, p 80 (2021)
Volume 13
Issue 1
Pharmaceutics, Vol 13, Iss 80, p 80 (2021)
In this study, we developed a control strategy for a drug product prepared by high-shear wet granulation and roller compaction using integrated quality by design (QbD). During the first and second stages, we optimized the process parameters through t
Autor:
Eun-Seok Park, Jae-Cheol Choi, Chun-Woong Park, Yong-Bin Kwon, Ji-Hyun Kang, Dong-Wook Kim, Myung-Hee Chun, Mi-Seo Cho
Publikováno v:
Drug development and industrial pharmacy. 46(5)
Metformin hydrochloride (MFM) is often used as a controlled-release (CR) tablet to reduce dosing frequency. However, the MFM CR tablet contains significant amounts of excipients and the tablet size is also large. Dosing convenience and patient compli
Publikováno v:
BMC Molecular and Cell Biology, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Doxorubicin (DOX), which is widely used in cancer treatment, can induce cardiomyopathy. One of the main mechanisms whereby DOX induces cardiotoxicity involves pyroptosis through the NLR family pyrin domain containing 3 (NLRP3) inflammasome a
Externí odkaz:
https://doaj.org/article/7b0ffd8db7be4db682399ab0d0e60df3
Publikováno v:
Korean Journal of Construction Engineering and Management. 12:73-82
The term `green` has become an important way of survival for the construction industry in 21th century in accordance with the emergence of the environmental crisis due to the climatic change. Especially the policy of carbon taxation, planed to be int
Autor:
Jihye Bang, Kuk Hui Son, Hye-Ryeon Heo, Eunsook Park, Hyun-Jeong Kwak, Kyung-Ok Uhm, Myung-Hee Chung, Young-Youl Kim, Hyun Joung Lim
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1189 (2023)
Particulate matter 2.5 (PM2.5) induces lung injury by increasing the generation of reactive oxygen species (ROS) and inflammation. ROS aggravates NLRP3 inflammasome activation, which activates caspase-1, IL-1β, and IL-18 and induces pyroptosis; thes
Externí odkaz:
https://doaj.org/article/2114eb8a15fe464fb4aad3506ff6cb17
Autor:
Dong Hyun Kim, Sang-Taek Im, Jin Young Yoon, Seunghoon Kim, Mee Kum Kim, Myung-Hee Chung, Chul-Kyu Park
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract We compared the therapeutic effects of topical 8-oxo-2′-deoxyguanosine (8-oxo-dG) and corticosteroid in a murine ocular alkali burn model. (n = 128) The corneal alkali burn model was established by applying 0.1 N sodium hydroxide (NaOH), f
Externí odkaz:
https://doaj.org/article/6a2215f2c09e4cc8983cac2fc369f89c
Autor:
Seunghoon Kim, Ye Won Jang, Young-ah Ku, Yungyeong Shin, Md Mahbubur Rahman, Myung-Hee Chung, Yong Ho Kim, Dong Hyun Kim
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The ocular surface is continuously exposed to various environmental factors, and innate and adaptive immunity play crucial roles in ocular surface diseases (OSDs). Previously, we have reported that the topical application of RCI001 affords excellent
Externí odkaz:
https://doaj.org/article/3a523164942448928af3fdb190976b63
Autor:
Yonghyun Kim, Chang-Young Oh, Won-Hun Ham, Myung-Hee Chun, Youn-Jung Yoon, Jae-Eun Joo, Yiu-Suk Lee, Kee-Young Lee
Publikováno v:
Archives of pharmacal research. 27(2)
In this study, a highly diastereoselective synthesis of anti-1,2-aminoalcohol was explored starting from L-amino acids as chiral sources. The higher yield and diastereoselectivity was shown when the aza-Claisen rearrangement was performed with allyli