Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Myung-Gyun Kang"'
Autor:
Jong Min Oh, Hyun-Jae Jang, Myung-Gyun Kang, Soobin Song, Doo-Young Kim, Jung‑Hee Kim, Ji-In Noh, Jong Eun Park, Daeui Park, Sung-Tae Yee, Hoon Kim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Among 276 herbal extracts, a methanol extract of Castanopsis cuspidata var. sieboldii stems was selected as an experimental source for novel acetylcholinesterase (AChE) inhibitors. Five compounds were isolated from the extract by activity-gu
Externí odkaz:
https://doaj.org/article/4bf6a6a34e9b438b8713b789b7d987c9
Autor:
Jeong Hyun Heo, Bo Hyun Eom, Hyung Won Ryu, Myung-Gyun Kang, Jong Eun Park, Doo-Young Kim, Jung-Hee Kim, Daeui Park, Sei-Ryang Oh, Hoon Kim
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Cholinesterase (ChE) and monoamine oxidase (MAO) inhibitors have been attracted as candidate treatments for Alzheimer's disease (AD). Fifteen khellactone-type coumarins from the roots of Peucedanum japonicum Thunberg were tested for acetylch
Externí odkaz:
https://doaj.org/article/d72ac436ee4c457682405caf23d94355
Autor:
Jong Min Oh, Hyun-Jae Jang, Myung-Gyun Kang, Seul-Ki Mun, Daeui Park, Su-Jin Hong, Min Ha Kim, Soo-Young Kim, Sung-Tae Yee, Hoon Kim
Publikováno v:
Molecules, Vol 28, Iss 1, p 258 (2022)
Thirteen compounds were isolated from the Canavalia lineata pods and their inhibitory activities against human monoamine oxidase-A (hMAO-A) and -B (hMAO-B) were evaluated. Among them, compounds 8 (medicarpin) and 13 (homopterocarpin) showed potent in
Externí odkaz:
https://doaj.org/article/9953de67c61a480aa8c5c689267596bc
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Drug-induced liver injury (DILI) is one of the major reasons for termination of drug development. Due to the importance of predicting DILI in early phases of drug development, diverse in silico models have been developed to filter out DILI-causing ca
Externí odkaz:
https://doaj.org/article/99e6c26044fe4c3b9375b10149e825df
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231049 (2020)
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that has attracted global attention and international awareness. ZIKV infection exhibits mild symptoms including fever and pains; however, ZIKV has recently been shown to be related to increa
Externí odkaz:
https://doaj.org/article/954cdb20ceeb4c57ac4d08c5787fa18d
Autor:
Myung-Gyun Kang, Nam Sook Kang
Publikováno v:
Molecules, Vol 26, Iss 24, p 7548 (2021)
Drug-induced liver injury (DILI) is a major concern for drug developers, regulators, and clinicians. However, there is no adequate model system to assess drug-associated DILI risk in humans. In the big data era, computational models are expected to p
Externí odkaz:
https://doaj.org/article/7507ba129a834b74b9dff93e98decc63
Autor:
Geum Seok Jeong, Prima F. Hillman, Myung-Gyun Kang, Sungbo Hwang, Jong-Eun Park, Sang-Jip Nam, Daeui Park, Hoon Kim
Publikováno v:
Journal of Fungi, Vol 7, Iss 10, p 876 (2021)
Using 126 endogenous lichen fungus (ELF) extracts, inhibitory activities against monoamine oxidases (MAOs) and cholinesterases (ChEs) were evaluated. Among them, extract ELF29 of the endogenous fungus Diaporthe mahothocarpus of the lichen Cladonia sy
Externí odkaz:
https://doaj.org/article/b4f90dabc95f46ed9c92dd3f69e7c495
Autor:
Geum-Seok Jeong, Myung-Gyun Kang, Sang-Ah Han, Ji-In Noh, Jong-Eun Park, Sang-Jip Nam, Daeui Park, Sung-Tae Yee, Hoon Kim
Publikováno v:
Journal of Fungi, Vol 7, Iss 2, p 84 (2021)
Inhibitory activities against monoamine oxidases (MAOs) and cholinesterases (ChEs) and antioxidant activity were evaluated for 195 extracts from Ukraine-derived endogenous lichen fungi (ELF). Among them, an ELF13 (identified as Daldinia fissa) extrac
Externí odkaz:
https://doaj.org/article/7e77930387b14d3dba79c20a6fc6281b
Publikováno v:
Molecules, Vol 25, Iss 18, p 4089 (2020)
We evaluated the anti-inflammatory effects of SNAH in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages by performing nitric oxide (NO) assays, cytokine enzyme-linked immunosorbent assays, Western blotting, and real-time reverse transcription
Externí odkaz:
https://doaj.org/article/320f4f60fbd34eb8bc5e8d3ff70b7490
Autor:
Geum Seok Jeong, Myung-Gyun Kang, Joon Yeop Lee, Sang Ryong Lee, Daeui Park, MyoungLae Cho, Hoon Kim
Publikováno v:
Molecules, Vol 25, Iss 17, p 3896 (2020)
Eight compounds were isolated from the roots of Glycyrrhiza uralensis and tested for cholinesterase (ChE) and monoamine oxidase (MAO) inhibitory activities. The coumarin glycyrol (GC) effectively inhibited butyrylcholinesterase (BChE) and acetylcholi
Externí odkaz:
https://doaj.org/article/a12e1cde4d28456e89c9ec66cac6a238