Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Myung S. Kim"'
Autor:
Alyson Haslam, Jennifer Gill, Tyler Crain, Diana Herrera-Perez, Emerson Y. Chen, Talal Hilal, Myung S. Kim, Vinay Prasad
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Identifying ineffective practices that have been used in oncology is important in reducing wasted resources and harm. We sought to examine the prevalence of practices that are being used but have been shown in RCTs to be ineffecti
Externí odkaz:
https://doaj.org/article/9585014a1c5c464484848683b3b378c5
Autor:
Myung S. Kim, Vinay Prasad
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 149:1357-1360
The current approval indications for pembrolizumab are complex, reflecting the inclusion criteria of numerous clinical trials that led to approvals. Here we argue that allowing the use of pembrolizumab to any advanced solid tumor in any tumor type in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2527bd8572573641c5f78fcb8fc2cc1f
https://doi.org/10.1007/s00432-022-04412-4
https://doi.org/10.1007/s00432-022-04412-4
Publikováno v:
European Journal of Cancer. 160:175-179
Aim Drug approvals for genome-informed indications have been increasing in recent years, but it is unknown how many of them have demonstrated an improvement in overall survival (OS). We assessed the frequency of approved genome-informed drugs demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c63de6977b281bb1811a442f02198d9
https://doi.org/10.1016/j.ejca.2021.10.028
https://doi.org/10.1016/j.ejca.2021.10.028
Autor:
Vinay Prasad, Myung S. Kim
Publikováno v:
European Journal of Cancer. 155:163-167
The design of clinical trials with outcomes reported in cohorts including nested subgroups is common in novel agents seeking new indications for approval. This structure represents a tension between drug companies that have an incentive to pursue bro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5005030bb3b8c3325362c1ba442b5e88
https://doi.org/10.1016/j.ejca.2021.06.058
https://doi.org/10.1016/j.ejca.2021.06.058
Publikováno v:
Annals of Oncology. 32:926-932
Background Prior studies have evaluated the percentage of cancer patients with advanced or metastatic cancer who are eligible for and respond to genome-targeted therapy, but since that publication, the number of Food and Drug Administration (FDA) app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0ebecb435733ed2950b8807313cc2e
https://doi.org/10.1016/j.annonc.2021.04.003
https://doi.org/10.1016/j.annonc.2021.04.003
Autor:
Vinay Prasad, Myung S. Kim
Publikováno v:
European Journal of Cancer. 154:1-3
The expanding list of treatment options available to patients with cancer is a source of excitement. Drugs with novel mechanisms of action receive attention at academic meetings and approval of novel drugs are cited as a victory of medical research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af856cc9a85cefec76cf813a458f4f60
https://doi.org/10.1016/j.ejca.2021.04.047
https://doi.org/10.1016/j.ejca.2021.04.047
Autor:
Zoe L. Lyski, Myung S. Kim, David Xthona Lee, Hans-Peter Raué, Vikram Raghunathan, Janet Griffin, Debbie Ryan, Amanda E. Brunton, Marcel E. Curlin, Mark K. Slifka, William B. Messer, Stephen E. Spurgeon
Publikováno v:
Blood Advances
Chronic Lymphocytic Leukemia (CLL) is predominantly a B-lymphocyte leukemia associated with immune defects that are often exacerbated by CLL directed therapies. SARS-CoV-2 infection poses a significant risk of illness or mortality to CLL patients, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5860632dd2898e63b6202fe9278fac19
https://doi.org/10.1101/2021.11.04.21265948
https://doi.org/10.1101/2021.11.04.21265948
Publikováno v:
Journal of cancer policy. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f994312125d9df1bcc9c39f7c5bb9413
https://pubmed.ncbi.nlm.nih.gov/35559866
https://pubmed.ncbi.nlm.nih.gov/35559866
Publikováno v:
JAMA Intern Med
This cross-sectional study quantifies the number of randomized clinical trials in the literature for each indication for stem cell transplantation by disease type and status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0903f2efe1cb4500bc1792e2953fd346
https://pubmed.ncbi.nlm.nih.gov/34491275
https://pubmed.ncbi.nlm.nih.gov/34491275
Autor:
Emerson Y. Chen, Vinay Prasad, Talal Hilal, Myung S. Kim, Jennifer Gill, Tyler Crain, Alyson Haslam, Diana Herrera-Perez
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Cancer
BMC Cancer
Background Identifying ineffective practices that have been used in oncology is important in reducing wasted resources and harm. We sought to examine the prevalence of practices that are being used but have been shown in RCTs to be ineffective (medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fad83a8ef588eeaf92b2fc3833a5ae1
https://doi.org/10.1186/s12885-021-08632-8
https://doi.org/10.1186/s12885-021-08632-8