Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Myung Rae Park"'
Autor:
Donggyu Nam, Myung Rae Park, Hyunah Lee, Sung Chul Bae, Daniela Gerovska, Marcos J. Araúzo-Bravo, Holm Zaehres, Hans R. Schöler, Jeong Beom Kim
Publikováno v:
Cells, Vol 11, Iss 14, p 2242 (2022)
The transplantation of pluripotent stem cell (PSC)-derived liver organoids has been studied to solve the current donor shortage. However, the differentiation of unintended cell populations, difficulty in generating multi-lineage organoids, and tumori
Externí odkaz:
https://doaj.org/article/81ddc1848ea1448a890eb0cb609dfb45
Autor:
Myung Rae Park, Man Sze Wong, Marcos J Araúzo-Bravo, Hyunah Lee, Donggyu Nam, Soo Yong Park, Hong Dae Seo, Sang Min Lee, Hans Florian Zeilhofer, Holm Zaehres, Hans R Schöler, Jeong Beom Kim
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221085 (2019)
Direct conversion from fibroblasts to generate hepatocyte like-cells (iHeps) bypassing the pluripotent state has been described in previous reports as an attractive method acquiring hepatocytes for cell-based therapy. The limited proliferation of iHe
Externí odkaz:
https://doaj.org/article/98b0d3260f9142dca4a288c00ac79fa8
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40
Objective: Vascular progenitor cells (VPCs), which are able to differentiate into both endothelial cells and smooth muscle cells, have the potential for treatment of ischemic diseases. Generated by pluripotent stem cells, VPCs carry the risk of tumor
Publikováno v:
Biomedical Journal of Scientific & Technical Research. 20
40% of medicines were induced from natural resources while one candidate could be available from 5,000 organic syntheses. It is therefore important to screen the effective materials from natural medicine to ultimately scale up the effective component
Autor:
Donggyu Nam, Man Sze Wong, Soo Yong Park, Hans R. Schöler, Myung Rae Park, Jeong Beom Kim, Holm Zaehres, Hong Dae Seo, Hans Florian Zeilhofer, Hyunah Lee, Sang Min Lee, Marcos J. Araúzo-Bravo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0221085 (2019)
PLoS ONE, Vol 14, Iss 8, p e0221085 (2019)
Direct conversion from fibroblasts to generate hepatocyte like-cells (iHeps) bypassing the pluripotent state has been described in previous reports as an attractive method acquiring hepatocytes for cell-based therapy. The limited proliferation of iHe
Publikováno v:
Biomaterials. 270:120688
Culturing autologous cells with therapeutic potential derived from a patient within a bioactive scaffold to induce functioning tissue formation is considered the ideal methodology towards realizing patient-specific regenerative medicine. Hydrogels ar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:127347
Human pluripotent stem cells (hPSCs) are a useful cell source for regenerative medicine. Despite having a potential of hPSCs for cell-based therapy, there is a need for a selective human pluripotency sensor for monitoring of live hPSCs. Here, we repo
Autor:
Hyunah Lee, Myung Rae Park, Seok Jin Lee, Donggyu Nam, Kyujin Hwang, Holm Zaehres, Jeong Beom Kim, Marcos J. Araúzo-Bravo, Kook In Park
The generation of patient-specific oligodendrocyte progenitor cells (OPCs) holds great potential as an expandable cell source for cell replacement therapy as well as drug screening in spinal cord injury or demyelinating diseases. Here, we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83c2f05853ec5340d66d139b827fa68
https://europepmc.org/articles/PMC4687687/
https://europepmc.org/articles/PMC4687687/
Publikováno v:
Advanced Science and Technology Letters.
Recent advances in direct conversion technology are of great significance in neuro-regenerative medicine. Conversion of somatic cells to a desired cell type is next generation reprogramming technology for clinical applications. The novel strategy of
Autor:
Mukesh Kumar Gupta, Myung Rae Park, Hoon Taek Lee, Ziban Chandra Das, Sang Jun Uhm, Hye Ran Lee
Publikováno v:
Theriogenology. 75(5)
Phosphatidylinositol-3-kinases (PI3Ks) play pivotal roles in meiotic progression of oocytes from metaphase I to metaphase II stage. Using a Class III-specific inhibitor of PI3K, 3-methyladenine (3MA), this study shows that Class III PI3K may be essen