Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Myung G. Lee"'
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 11, Iss 1 (2008)
To test the effect of insulin treatment on the pharmacokinetics of metformin in rats with diabetes mellitus induced by alloxan (DMIA rats). The following results were reported from other studies. Metformin was metabolized via hepatic CYP2C11, 2D1, an
Externí odkaz:
https://doaj.org/article/86866efae13f4b15a30af9ee26453e03
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 10, Iss 4 (2007)
Purpose. To investigate the effect of diabetes mellitus induced by alloxan (DMIA) or streptozotocin (DMIS) on the pharmacokinetics of omeprazole in rats. It has been reported that omeprazole is primarily metabolized via hepatic CYP1A2, 2D1, and 3A1 i
Externí odkaz:
https://doaj.org/article/1d6902b03c0c44b385b892f75440a7bf
Publikováno v:
Journal of Pharmacy and Pharmacology. 61:1637-1642
Objectives It has been reported that hepatic cytochrome P450 (CYP)2C9 and CYP3A4 are responsible for the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in humans. However, in-vivo studies in rats have not been report
Publikováno v:
Animal Science Journal. 78:535-540
This comparative study was to investigate the hypocholesterolemic effects of dietary Rhodopseudomonas palustris and Rhodobacter capsulatus on rats fed a high cholesterol diet. Thirty male Wister–Imamichi rats were assigned to three groups and fed o
Publikováno v:
Research communications in molecular pathology and pharmacology.
Pharmacokinetic parameters of DA-8159 and one of its metabolites, DA-8164, were compared after intravenous and oral administration of DA-8159 at a dose of 30 mg/kg to control rats and rats pretreated with Klebsiella pneumoniae lipopolysaccharide (KPL
Publikováno v:
Research communications in molecular pathology and pharmacology.
Pharmacokinetics of itraconazole was measured after 1-min intravenous infusion at a dose of 10 mg/kg to male New Zealand white rabbits. The terminal half-life of itraconazole was 524 min. Itraconazole was eliminated slowly in rabbits with total body
Autor:
Eun J, Lee, Eun J, Kim, Yoon G, Kim, Hye C, Chung, So H, Kim, Dong H, Kim, Inchul, Lees, Sang G, Kim, Myung G, Lee
Publikováno v:
Research communications in molecular pathology and pharmacology.
It has been reported that the total body clearance (CL) of 2-(allylthio)pyrazine (2-AP) was significantly faster after intravenous administration of 2-AP to rats pretreated with 3-methylcholanthrene, phenobarbital, and dexamethasone (main inducers of
Publikováno v:
International journal of pharmaceutics. 330(1-2)
The aim of this study is to report the pharmacokinetics of omeprazole after intravenous (20 mg/kg) and oral (40 mg/kg) administration to rats with liver cirrhosis induced by dimethylnitrosamine (cirrhotic rats) with respect to CYP isozyme changes. Th
Publikováno v:
Research communications in molecular pathology and pharmacology.
Pharmacokinetic and pharmacodynamic parameters were evaluated after an intravenous administration of torasemide at a dose of 10 mg/kg to control rats and rats with acute renal failure induced by uranyl nitrate (U-ARF). In rats with U-ARF, the total a
Autor:
Eun J, Lee, Eun J, Kim, Yoon G, Kim, Hye C, Chung, So H, Kim, Dong H, Kim, Inchul, Lee, Sang G, Kim, Myung G, Lee
Publikováno v:
Research communications in molecular pathology and pharmacology. 111(5-6)
It was reported that the total body clearance (CL) of 2-(allylthio)pyrazine (2-AP) was significantly faster after intravenous administration of 2-AP to rats pretreated with 3-methylcholanthrene (an inducer of CYP1A1/2 and 2E1 in rats) than that in co