Zobrazeno 1 - 10
of 387
pro vyhledávání: '"Myron S Czuczman"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionRegulatory T cell (Treg)-targeting cancer immunotherapy aims to transiently deplete Treg cells in the tumor microenvironment, without affecting effector T cells (Teff), thus both enhancing anti-tumor activity and avoiding autoimmunity. Th
Externí odkaz:
https://doaj.org/article/c25ee8c9bb24464ebab7d9dc7200886e
Autor:
Jeffrey M. Venstrom, Lewis L. Lanier, Lawrence Kaplan, Bruce Cheson, Myron S. Czuczman, Katharine Hsu, Lili Zhou, Sin-Ho Jung, Jeffrey Johnson, Brandelyn N. Pitcher, Sandra Lopez-Verges, Juan Du
Natural killer (NK) cells contribute to clinical responses in patients treated with rituximab, but the rules determining NK-cell responsiveness to mAb therapies are poorly defined. A deeper understanding of the mechanisms responsible for antibody-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::812db7c64d2fe9e907d54d34e9bc74c2
https://doi.org/10.1158/2326-6066.c.6548456.v1
https://doi.org/10.1158/2326-6066.c.6548456.v1
Autor:
Jeffrey M. Venstrom, Lewis L. Lanier, Lawrence Kaplan, Bruce Cheson, Myron S. Czuczman, Katharine Hsu, Lili Zhou, Sin-Ho Jung, Jeffrey Johnson, Brandelyn N. Pitcher, Sandra Lopez-Verges, Juan Du
Exclusion gating technique and NK cell flow cytometric analysis to determine the effector potency of individual NK cell populations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29883576173bb46d6c5ea2cd5ad144b3
https://doi.org/10.1158/2326-6066.22537469.v1
https://doi.org/10.1158/2326-6066.22537469.v1
Autor:
Jeffrey M. Venstrom, Lewis L. Lanier, Lawrence Kaplan, Bruce Cheson, Myron S. Czuczman, Katharine Hsu, Lili Zhou, Sin-Ho Jung, Jeffrey Johnson, Brandelyn N. Pitcher, Sandra Lopez-Verges, Juan Du
Proportion of CD56brightCD16dim and CD56dimCD16bright NK cells within KIR-, unlicensed, and licensed NK cell subsets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b477a18099143cfc61090ee168a35b
https://doi.org/10.1158/2326-6066.22537460
https://doi.org/10.1158/2326-6066.22537460
Autor:
Jeffrey M. Venstrom, Lewis L. Lanier, Lawrence Kaplan, Bruce Cheson, Myron S. Czuczman, Katharine Hsu, Lili Zhou, Sin-Ho Jung, Jeffrey Johnson, Brandelyn N. Pitcher, Sandra Lopez-Verges, Juan Du
Rituximab increases cytotoxicity mediated by unlicensed NK cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e855e65c1737840f13b893cb80e289
https://doi.org/10.1158/2326-6066.22537463
https://doi.org/10.1158/2326-6066.22537463
Autor:
Jeffrey M. Venstrom, Lewis L. Lanier, Lawrence Kaplan, Bruce Cheson, Myron S. Czuczman, Katharine Hsu, Lili Zhou, Sin-Ho Jung, Jeffrey Johnson, Brandelyn N. Pitcher, Sandra Lopez-Verges, Juan Du
NK cell licensing endows a "missing self" response to HLA class I-deficient K562 myeloid cell line.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922af783159999ffbcfcacef8c55d039
https://doi.org/10.1158/2326-6066.22537466.v1
https://doi.org/10.1158/2326-6066.22537466.v1
Autor:
Jeffrey M. Venstrom, Lewis L. Lanier, Lawrence Kaplan, Bruce Cheson, Myron S. Czuczman, Katharine Hsu, Lili Zhou, Sin-Ho Jung, Jeffrey Johnson, Brandelyn N. Pitcher, Sandra Lopez-Verges, Juan Du
IL-2 stimulation of unlicensed NK cell degranulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2c50476d230a5122fc329145674163
https://doi.org/10.1158/2326-6066.22537457.v1
https://doi.org/10.1158/2326-6066.22537457.v1
Autor:
Ian D. Lewis, Dale Song, Pierre Fustier, Patrick Hagner, Anjan Thakurta, Jacqueline Russo, Chih-Jian Lih, P. Mickey Williams, Yandan Yang, Louis M. Staudt, George W. Wright, Pier Luigi Zinzani, Thomas E. Witzig, Gilles Salles, Francisco J. Hernandez-Ilizaliturri, David A. Eberhard, Pierre Brousset, Graham W. Slack, Randy D. Gascoyne, Nina Wagner-Johnston, Kim M. Linton, Simon Rule, Andrew Davies, Marek Trněný, Myron S. Czuczman
Investigator's Choice (IC) Dosing Regimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b054c13e02bc6939aaccf418b66f26
https://doi.org/10.1158/1078-0432.22467816.v1
https://doi.org/10.1158/1078-0432.22467816.v1
Autor:
Myron S. Czuczman, Scott H. Olejniczak, Naveen Bangia, Francisco J. Hernandez-Ilizaliturri, Ping-Chiao Tsai
Purpose: The aim of this research was to further investigate the contribution of CD20 antigen expression to rituximab activity and define the mechanisms responsible for CD20 downregulation in rituximab-resistant cell lines (RRCL).Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268b94d750a7ab1a260e523e8a7f4bc6
https://doi.org/10.1158/1078-0432.c.6520134.v1
https://doi.org/10.1158/1078-0432.c.6520134.v1