Zobrazeno 1 - 10
of 1 408
pro vyhledávání: '"Myron R"'
Autor:
Elizabeth Skapinker, Emilyn B. Aucoin, Haley L. Kombargi, Abdulrahman M. Yaish, Yunfan Li, Leili Baghaie, Myron R. Szewczuk
Publikováno v:
Cells, Vol 13, Iss 20, p 1739 (2024)
Cytokines can promote various cancer processes, such as angiogenesis, epithelial to mesenchymal transition (EMT), invasion, and tumor progression, and maintain cancer stem-cell-like (CSCs) cells. The mechanism(s) that continuously promote(s) tumors t
Externí odkaz:
https://doaj.org/article/d437dc0c6df942fb9365c426c290623b
Publikováno v:
Cells, Vol 13, Iss 6, p 480 (2024)
Understanding the role of biased G protein-coupled receptor (GPCR) agonism in receptor signaling may provide novel insights into the opposing effects mediated by cannabinoids, particularly in cancer and cancer metastasis. GPCRs can have more than one
Externí odkaz:
https://doaj.org/article/0a362f5b792b45c6b2bea7d363dc6356
Autor:
Leili Baghaie, Fiona Haxho, Fleur Leroy, Beth Lewis, Alexander Wawer, Shamano Minhas, William W. Harless, Myron R. Szewczuk
Publikováno v:
Cells, Vol 12, Iss 23, p 2767 (2023)
Surgery-induced tumor growth acceleration and synchronous metastatic growth promotion have been observed for decades. Surgery-induced wound healing, orchestrated through growth factors, chemokines, and cytokines, can negatively impact patients harbor
Externí odkaz:
https://doaj.org/article/150cfeac151344a49ec2a3c4501e7cca
Autor:
Leili Baghaie, Fleur Leroy, Mehdi Sheikhi, Abdollah Jafarzadeh, Myron R. Szewczuk, Abdolkarim Sheikhi
Publikováno v:
Viruses, Vol 15, Iss 10, p 2079 (2023)
Mutations and the glycosylation of epitopes can convert immunogenic epitopes into non-immunogenic ones via natural selection or evolutionary pressure, thereby decreasing their sensitivity to neutralizing antibodies. Based on Thomas Francis’s theory
Externí odkaz:
https://doaj.org/article/c163102be4574bfaa16d9dac3d686af7
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/715dae2a83c644899c9b6d18a534dc5c
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2142 (2023)
Our understanding of angiogenesis has significantly expanded over the past five decades. More recently, research has focused on this process at a more molecular level, looking at it through the signaling pathways that activate it and its non-direct d
Externí odkaz:
https://doaj.org/article/96fc78c81671450eb1d39c0af86002e7
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 807 (2023)
Since the discovery of insulin over 100 years ago, our understanding of the insulin signaling pathway has greatly expanded [...]
Externí odkaz:
https://doaj.org/article/c6cb9737c8574d96a158ac5aaf3a9ffa
Publikováno v:
Cells, Vol 12, Iss 9, p 1332 (2023)
We discovered a novel therapeutic target critical for SARS-CoV-2, cellular infectivity and the induction of the cytokine release syndrome. Here, we show that the mammalian enzyme neuraminidase-1 (Neu-1) is part of a highly conserved signaling platfor
Externí odkaz:
https://doaj.org/article/ec6a093080f4491495b262426dc6a870
Autor:
William Khoury, Ryan Trus, Xingyu Chen, Leili Baghaie, Mira Clark, Myron R. Szewczuk, Mohammad El-Diasty
Publikováno v:
Cells, Vol 12, Iss 8, p 1199 (2023)
Angiogenesis is the physiological process of developing new blood vessels to facilitate the delivery of oxygen and nutrients to meet the functional demands of growing tissues. It also plays a vital role in the development of neoplastic disorders. Pen
Externí odkaz:
https://doaj.org/article/ccd60b2fa75f4713abff980277d5930b
Autor:
Merlin Jesso Abraham, Adham El Sherbini, Mohammad El-Diasty, Sussan Askari, Myron R. Szewczuk
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 318 (2023)
Epigenetic reprogramming predicts the long-term functional health effects of health-related metabolic disease. This epigenetic reprogramming is activated by exogenous or endogenous insults, leading to altered healthy and different disease states. The
Externí odkaz:
https://doaj.org/article/255aaf60956a445fb54cb79b962502f8