Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Myron Gibert"'
Autor:
Roger Abounader, Emanuel Petricoin, See Phan, David Schiff, Julia Wulfkuhle, Isela Gallagher, Karim Saoud, Ciana Deveau, Baomin Wang, Fadila Guessous, Collin Dube, Mary Pahuski, Cassandra Grello, Madison Oxford, Fang Yuan, Myron Gibert, Sarah Hine, Ying Zhang, Nichola Cruickshanks
Purpose:Glioblastoma (GBM) is the most common and most lethal primary malignant brain tumor. The receptor tyrosine kinase MET is frequently upregulated or overactivated in GBM. Although clinically applicable MET inhibitors have been developed, resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e87c3eb9e23819597034c082110d07f
https://doi.org/10.1158/1078-0432.c.6529293.v1
https://doi.org/10.1158/1078-0432.c.6529293.v1
Autor:
Roger Abounader, Emanuel Petricoin, See Phan, David Schiff, Julia Wulfkuhle, Isela Gallagher, Karim Saoud, Ciana Deveau, Baomin Wang, Fadila Guessous, Collin Dube, Mary Pahuski, Cassandra Grello, Madison Oxford, Fang Yuan, Myron Gibert, Sarah Hine, Ying Zhang, Nichola Cruickshanks
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40125f8bc84279a9e294f1e45f9e4b63
https://doi.org/10.1158/1078-0432.22476102
https://doi.org/10.1158/1078-0432.22476102
Autor:
Ying Zhang, Feng Yuan, Cassandra Grello, Brian Reon, Myron Gibert, Collin Dube, Anindya Dutta, Eric Holland, Roger Abounader
Publikováno v:
Neuro-Oncology. 24:vii39-vii40
P53 is frequently mutated in most human cancers, including glioblastoma (GBM). Many p53 mutants acquire gain-of-function oncogenic effects through only partially understood mechanisms. To investigate the role of gain-of-function mutant p53 (MUT-p53)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2949c1f034932953a836d60085493c6
https://doi.org/10.1093/neuonc/noac209.156
https://doi.org/10.1093/neuonc/noac209.156
Autor:
Roger Abounader, Aditya Sorot, Elizabeth Mulcahy, Esther Xu, Ying Zhang, Collin Dube, Myron Gibert, Swapnil K. Sonkusare, Edward Perez-Reyes, Matteo Ottolini
Publikováno v:
Neuro Oncol
Glioblastoma is the most common primary malignant brain tumor with a dismal median survival of 15 months. Calcium signaling regulates a plethora of cellular processes making it an ideal target for therapeutic intervention. Our group identified T-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45446ca12c35fb93fe73b482b536d7f
https://europepmc.org/articles/PMC8598599/
https://europepmc.org/articles/PMC8598599/
Autor:
Collin Dube, Ying Zhang, Shekhar Saha, Michelle Lai, Myron Gibert, Miguel Escalante, Elizabeth Mulcahy, Matteo Ottolini, Kadie Hudson, Ulas Yener, Sylwia Bednarek, Farina Hanif, Esther Xu, Aditya Sorot, Swapnil Sonkusare, Harald Sontheimer, Roger Abounader
Publikováno v:
Neuro-Oncology. 24:vii24-vii24
Glioblastoma (GBM) is the most common primary malignant brain tumor with a dismal median survival of 15 months. Calcium signaling regulates a plethora of cellular processes making it an ideal target for therapeutic intervention. T-type calcium channe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::665a0f97e37d0e2abd77685bc0e8547a
https://doi.org/10.1093/neuonc/noac209.092
https://doi.org/10.1093/neuonc/noac209.092
Autor:
Roger Abounader, Elizabeth Mulcahy, Ying Zhang, Camilo E. Fadul, Jungeun Kim, Rossymar Colon, Myron Gibert, Eric Devairakkam
Publikováno v:
Neuro Oncol
When brain metastasis develops, the prognosis of cancer is dismal. Insights into the biology of the primary cancer and the brain metastasis are necessary to inform more effective and targeted treatments. To study the role of microRNAs in brain metast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f47938b558257b72461f375666e0e46
https://doi.org/10.1093/neuonc/noaa215.113
https://doi.org/10.1093/neuonc/noaa215.113
Discovery and Therapeutic Exploitation of Mechanisms of Resistance to MET Inhibitors in Glioblastoma
Autor:
Mary Pahuski, David Schiff, Madison Oxford, Fadila Guessous, Karim Saoud, Collin Dube, Nichola Cruickshanks, Emanuel F. Petricoin, Isela Gallagher, Myron Gibert, Sarah Hine, Ying Zhang, Ciana Deveau, Fang Yuan, Julia Wulfkuhle, Cassandra Grello, S. Phan, Baomin Wang, Roger Abounader
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(2)
Purpose: Glioblastoma (GBM) is the most common and most lethal primary malignant brain tumor. The receptor tyrosine kinase MET is frequently upregulated or overactivated in GBM. Although clinically applicable MET inhibitors have been developed, resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60338439209c661d7757cee81231b33d
https://pubmed.ncbi.nlm.nih.gov/30201763
https://pubmed.ncbi.nlm.nih.gov/30201763
Publikováno v:
Cancers, Vol 9, Iss 7, p 87 (2017)
Cancers
Cancers
Glioblastoma (GBM) is a lethal brain tumor with dismal prognosis. Current therapeutic options, consisting of surgery, chemotherapy and radiation, have only served to marginally increase patient survival. Receptor tyrosine kinases (RTKs) are dysregula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52b547926c3cccf433aae71f421ff77
https://www.mdpi.com/2072-6694/9/7/87
https://www.mdpi.com/2072-6694/9/7/87
Autor:
Initha Setiady, Maeve Coughlan, Baomin Wang, Collin Dube, Cassandra Grello, Madison Oxford, Roger Abounader, Ciana Deveau, Yanzhi Yang, Fang Yuan, Ying Zhang, Nichola Cruickshanks, Karim Saoud, Myron Gibert
Publikováno v:
Cancers
Cancers, Vol 10, Iss 9, p 297 (2018)
Cancers, Vol 10, Iss 9, p 297 (2018)
The tumor suppressor and transcription factor p53 plays critical roles in tumor prevention by orchestrating a wide variety of cellular responses, including damaged cell apoptosis, maintenance of genomic stability, inhibition of angiogenesis, and regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3a0e31e9742aaf620086e3c99d71c6
https://doi.org/10.3390/cancers10090297
https://doi.org/10.3390/cancers10090297