Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Myron G, Best"'
Autor:
Maksym A. Jopek, Krzysztof Pastuszak, Sebastian Cygert, Myron G. Best, Thomas Wurdinger, Jacek Jassem, Anna J. Zaczek, Anna Supernat
Publikováno v:
IEEE Journal of Translational Engineering in Health and Medicine, Vol 12, Pp 306-313 (2024)
The field of cancer diagnostics has been revolutionized by liquid biopsies, which offer a bridge between laboratory research and clinical settings. These tests are less invasive than traditional biopsies and more convenient than routine imaging metho
Externí odkaz:
https://doaj.org/article/f8bdbbadc6a4484d810ec5d2b00b4317
Autor:
Mafalda Antunes-Ferreira, Silvia D’Ambrosi, Mohammad Arkani, Edward Post, Sjors G. J. G. In ‘t Veld, Jip Ramaker, Kenn Zwaan, Ece Demirel Kucukguzel, Laurine E. Wedekind, Arjan W. Griffioen, Mirjam Oude Egbrink, Marijke J. E. Kuijpers, Daan van den Broek, David P. Noske, Koen J. Hartemink, Siamack Sabrkhany, Idris Bahce, Nik Sol, Harm-Jan Bogaard, Danijela Koppers-Lalic, Myron G. Best, Thomas Wurdinger
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Liquid biopsy approaches offer a promising technology for early and minimally invasive cancer detection. Tumor-educated platelets (TEPs) have emerged as a promising liquid biopsy biosource for the detection of various cancer types. In this s
Externí odkaz:
https://doaj.org/article/9358e61d08a441cdb79204397fabd108
Autor:
Zahra Eslami-S, Luis Enrique Cortés-Hernández, Ilias Glogovitis, Mafalda Antunes-Ferreira, Silvia D’Ambrosi, Keerthi Kurma, Françoise Garima, Laure Cayrefourcq, Myron G. Best, Danijela Koppers-Lalic, Thomas Wurdinger, Catherine Alix-Panabières
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Platelets are active players in hemostasis, coagulation and also tumorigenesis. The cross-talk between platelets and circulating tumor cells (CTCs) may have various pro-cancer effects, including promoting tumor growth, epithelial-mesenchy
Externí odkaz:
https://doaj.org/article/ce14cb73445c48479eb61a85c74fbe12
Autor:
Mohammad Arkani, Azar Kianzad, Samara Jansen, A. Josien Smits, Edward Post, Jip Ramaker, Tonny Lagerweij, Sjors G. J. G. In’t Veld, David P. Noske, Anton Vonk Noordegraaf, Thomas Wurdinger, Myron G. Best, Harm‐Jan Bogaard
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 13 (2023)
Background Appropriate treatment of pulmonary hypertension (PH) is critically dependent on accurate discrimination between pre‐ and postcapillary PH. However, clinical discrimination is challenging and frequently requires a right heart catheterizat
Externí odkaz:
https://doaj.org/article/2bb1340cd1964acd909e02176b39be30
Autor:
Krzysztof Pastuszak, Anna Supernat, Myron G. Best, Sjors G.J.G. In 't Veld, Sylwia Łapińska‐Szumczyk, Anna Łojkowska, Robert Różański, Anna J. Żaczek, Jacek Jassem, Thomas Würdinger, Tomasz Stokowy
Publikováno v:
Molecular Oncology, Vol 15, Iss 10, Pp 2688-2701 (2021)
Liquid biopsies offer a minimally invasive sample collection, outperforming traditional biopsies employed for cancer evaluation. The widely used material is blood, which is the source of tumor‐educated platelets. Here, we developed the imPlatelet c
Externí odkaz:
https://doaj.org/article/adeeef4060b14a0db9cd2dae0a2c0c27
Autor:
Anna Supernat, Marta Popęda, Krzysztof Pastuszak, Myron G. Best, Peter Grešner, Sjors In ’t Veld, Bartłomiej Siek, Natalia Bednarz-Knoll, Matthew T. Rondina, Tomasz Stokowy, Thomas Wurdinger, Jacek Jassem, Anna J. Żaczek
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Blood platelet RNA-sequencing is increasingly used among the scientific community. Aberrant platelet transcriptome is common in cancer or cardiovascular disease, but reference data on platelet RNA content in healthy individuals are scarce an
Externí odkaz:
https://doaj.org/article/4fd18847df6c4fb09343afbf7e38a8f5
Autor:
Vera Manders, Allerdien Visser, Remco Keijser, Naomi Min, Ankie Poutsma, Joyce Mulders, Tarah van den Berkmortel, Marjolein Hortensius, Aldo Jongejan, Eva Pajkrt, Erik A. Sistermans, Daoud Sie, Myron G. Best, Tom Würdinger, Marjon de Boer, Gijs Afink, Cees Oudejans
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Using genome-wide transcriptome analysis by RNA sequencing of first trimester plasma RNA, we tested whether the identification of pregnancies at risk of developing pre-eclampsia with or without preterm birth or growth restriction is possible
Externí odkaz:
https://doaj.org/article/3ef67a8e8858492f80308c0b8c2b1912
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundGliomas are the most common and aggressive tumors of the central nervous system. A robust and widely used blood-based biomarker for glioma has not yet been identified. In recent years, a plethora of new research on blood-based biomarkers fo
Externí odkaz:
https://doaj.org/article/21d3cf8058be446a81a94f9116160cc7
Autor:
Noémie Kraaijpoel, Frits I. Mulder, Marc Carrier, Annabel van Lieshout, Tom Würdinger, Myron G. Best, Bart J.M. van Vlijmen, Yassene Mohammed, Luis Jara-Palomares, Pieter W. Kamphuisen, Marcello Di Nisio, Walter Ageno, Jan Beyer-Westendorf, Thomas Vanassche, Frederikus A. Klokm, Hans-Martin Otten, Mike J.L. Peters, Benilde Cosmi, Marije ten Wolde, Patrick M.M. Bossuyt, Harry R. Büller, Nick van Es
Publikováno v:
Thrombosis Update, Vol 2, Iss , Pp 100030- (2021)
Occult cancer is detected in about 5% of patients with unprovoked venous thromboembolism (VTE) in the 12 months following VTE diagnosis. Current guidance suggests conducting a ‘limited’ cancer screening in these patients, consisting of medical hi
Externí odkaz:
https://doaj.org/article/2dd9496a84fc4b7081e92959d00b7e2f
Autor:
Nik Sol, Sjors G.J.G. in ‘t Veld, Adrienne Vancura, Maud Tjerkstra, Cyra Leurs, François Rustenburg, Pepijn Schellen, Heleen Verschueren, Edward Post, Kenn Zwaan, Jip Ramaker, Laurine E. Wedekind, Jihane Tannous, Bauke Ylstra, Joep Killestein, Farrah Mateen, Sander Idema, Philip C. de Witt Hamer, Anna C. Navis, William P.J. Leenders, Ann Hoeben, Bastiaan Moraal, David P. Noske, W. Peter Vandertop, R. Jonas A. Nilsson, Bakhos A. Tannous, Pieter Wesseling, Jaap C. Reijneveld, Myron G. Best, Thomas Wurdinger
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101- (2020)
Summary: Tumor-educated platelets (TEPs) are potential biomarkers for cancer diagnostics. We employ TEP-derived RNA panels, determined by swarm intelligence, to detect and monitor glioblastoma. We assessed specificity by comparing the spliced RNA pro
Externí odkaz:
https://doaj.org/article/3c63ceb85e20460e8535824c45ce6bd6