Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Myriem Skander"'
Autor:
Thomas R. Ward, Jérôme Collot, Julieta Gradinaru, Andreas Loosli, Myriem Skander, Christophe Letondor, Edith Joseph, Gérard Klein
Publikováno v:
CHIMIA, Vol 57, Iss 10 (2003)
With the aim of exploring the role of the second coordination sphere in enantioselective catalysis, achiral organometallic catalyst precursors are anchored in proteins via non-covalent interactions. A chemogenetic procedure allows the activity and th
Externí odkaz:
https://doaj.org/article/74c836b2c92641868d4c4a204efa3b1a
Autor:
Tao Jia, Oumar Diane, Deepanjan Ghosh, Myriem Skander, Gaelle Fontaine, Pascal Retailleau, Joël Poupon, Jérôme Bignon, Ytabelle Maga Moulai Siasia, Vincent Servajean, Nathalie Hue, Jean-François Betzer, Angela Marinetti, Sophie Bombard
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2023, 66 (10), pp.6836-6848. ⟨10.1021/acs.jmedchem.3c00267⟩
Journal of Medicinal Chemistry, 2023, 66 (10), pp.6836-6848. ⟨10.1021/acs.jmedchem.3c00267⟩
International audience; Bioactive NHC-transition metal complexes have shown promise as anti-cancer agents, but their potential use as radiosensitizers has been neglected so far. We disclose here a new series of bimetallic platinum(II) complexes displ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5350758825484445abd2a2d5b6b0ba
https://doi.org/10.1021/acs.jmedchem.3c00267
https://doi.org/10.1021/acs.jmedchem.3c00267
Publikováno v:
Organometallics
Organometallics, American Chemical Society, 2009, 28 (1), pp.140-151. ⟨10.1021/om800743r⟩
Organometallics, American Chemical Society, 2009, 28 (1), pp.140-151. ⟨10.1021/om800743r⟩
International audience; Square-planar platinum(II) complexes that combine chiral diphosphines and NHC ligands have been obtained in high yields from (NHC)Pt(0)(dvtms) complexes, via an oxidative addition/ligand exchange sequence. The use of suitable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817247e5fade57c9b0a723544ae765d4
https://doi.org/10.1021/om800743r
https://doi.org/10.1021/om800743r
Publikováno v:
Organometallics
Organometallics, American Chemical Society, 2007, 26 (24), pp.5782-5785. ⟨10.1021/om700839y⟩
Organometallics, American Chemical Society, 2007, 26 (24), pp.5782-5785. ⟨10.1021/om700839y⟩
A new synthetic approach allows access to axially chiral square-planar platinum(II) complexes by combining an enantiomerically pure diphosphine (DuPHOS, BPE, or Chiraphos) and an unsymmetric NHC li...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004d1135e3259347d7a2bb934470a4b0
https://doi.org/10.1021/om700839y
https://doi.org/10.1021/om700839y
Autor:
Thomas R. Ward, Andreas Loosli, Julieta Gradinaru, Myriem Skander, Andrea Zocchi, Gérard Klein, Jerome Collot, Jerome Sauser, Nicolas Humbert, François Gilardoni
Publikováno v:
Journal of the American Chemical Society. 126:14411-14418
We report on the generation of artificial metalloenzymes based on the noncovalent incorporation of biotinylated rhodium−diphosphine complexes in (strept)avidin as host proteins. A chemogenetic optimization procedure allows one to optimize the enant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2db7a416a88099278a9f6f7360b483
https://doi.org/10.1021/ja0476718
https://doi.org/10.1021/ja0476718
Autor:
Patrick Mailliet, Bernard Bourrie, Angela Marinetti, Pascal Retailleau, Myriem Skander, Laurent Schio
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (5), pp.2146-2154. ⟨10.1021/jm901693m⟩
Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (5), pp.2146-2154. ⟨10.1021/jm901693m⟩
N-Heterocyclic carbene (NHC) platinum complexes have been highlighted as a promising and original platform for building new cytotoxic drugs of the cisplatin series. Mixed NHC-amine Pt(II) complexes have been prepared via a facile and modular two step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c264d811da997c46be99b65f41e0ed79
https://hal.archives-ouvertes.fr/hal-00466326
https://hal.archives-ouvertes.fr/hal-00466326
Publikováno v:
ChemInform. 40
A new family of cyclometalated (N-heterocyclic carbene)-PtII complexes bearing monodentate phosphines as ancillary ligands has been designed for use as precatalysts in 1,6-enyne cycloisomerization reactions. Highly enantioselective skeletal rearrange
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::773242516d3e70944b58b796491e87b2
https://doi.org/10.1002/chin.200940139
https://doi.org/10.1002/chin.200940139
Publikováno v:
Organic Letters
Organic Letters, American Chemical Society, 2009, 11 (10), pp.2137-9. ⟨10.1021/ol900724z⟩
Organic Letters, American Chemical Society, 2009, 11 (10), pp.2137-9. ⟨10.1021/ol900724z⟩
International audience; A new family of cyclometalated (N-heterocyclic carbene)-Pt(II) complexes bearing monodentate phosphines as ancillary ligands has been designed for use as precatalysts in 1,6-enyne cycloisomerization reactions. Highly enantiose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc301455549aba2278222d7766ac2a17
https://pubmed.ncbi.nlm.nih.gov/19374390
https://pubmed.ncbi.nlm.nih.gov/19374390
Nous décrivons nos efforts de recherche dans la création de métalloenzymes artificielles efficaces dans l'hydrogénation énantiosélective de déhydroaminoacides N-protégés. L'introduction d'un espaceur (R)-proline entre le résidu biotinyle et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc573870b2bcb398581800f3a098986a
http://doc.rero.ch/record/8340/files/Rusbandi_Untung_E._-_Second-generation_artificial_hydrogenases_20071116.pdf
http://doc.rero.ch/record/8340/files/Rusbandi_Untung_E._-_Second-generation_artificial_hydrogenases_20071116.pdf
Autor:
Nicolas Humbert, Anita Ivanova, Untung E. Rusbandi, Cheikh Lo, Thomas R. Ward, Marc Creus, Myriem Skander
We report on our efforts to create efficient artificial metalloenzymes for the enantioselective hydrogenation of N-protected dehydroamino acids using either avidin or streptavidin as host proteins. Introduction of chiral amino acid spacers - phenylal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee2b2f0247ee238835379dcbb255d11
http://doc.rero.ch/record/8342/files/Rusbandi_Untung_E._-_Second_Generation_Artificial_Hydrogenases_20071116.pdf
http://doc.rero.ch/record/8342/files/Rusbandi_Untung_E._-_Second_Generation_Artificial_Hydrogenases_20071116.pdf