Biomarkers of inflammation and innate immunity in atrophic nonunion fracture

Autor: Jean-Philippe Hauzeur, Dominique de Seny, Michel Malaise, Myrielle Mathieu, Gaël Cobraiville, Charlotte Collin, Pierre Leprince, Marianne Fillet, Valérie Gangji

Publikováno v: Journal of Translational Medicine
Journal of translational medicine, 14 (1

Background: Nonunion is a failure of healing following a bone fracture. Its physiopathology remains partially unclear and the discovery of new mediators could promote the understanding of bone healing. Methods: Thirty-three atrophic nonunion (NU) pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c2af81e9315a780b8fa8cef542c10d
https://doi.org/10.1186/s12967-016-1019-1

Activin-A, Transforming Growth Factor-β, and Myostatin Signaling Pathway in Experimental Dilated Cardiomyopathy

Autor: Pascale Jespers, Laurence Dewachter, Myrielle Mathieu, Robert Naeije, Kathleen McEntee, Ielham Hadad, Serge Brimioulle, Maryam Mahmoudabady, Lynn Ray

Publikováno v: Journal of Cardiac Failure. 14:703-709

Background The pathogenic mechanisms of dilated cardiomyopathy are still uncertain. A number of cytokines and growth factors participate in the remodeling process of the disease. Methods We investigated the cardiac myostatin, transforming growth fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c0cba7d4dd9c8e043c9620b4e0d0e4
https://doi.org/10.1016/j.cardfail.2008.05.003

Glucose-Dependent Insulinotropic Peptide Prevents Serum Deprivation-Induced Apoptosis in Human Bone Marrow-Derived Mesenchymal Stem Cells and Osteoblastic Cells

Autor: Sabrina Rigutto, Jessica Berlier, A. Dalla Valle, Joanne Rasschaert, J Zhang, Valérie Gangji, Ilham Kharroubi, Myrielle Mathieu

Publikováno v: Stem cell reviews and reports. 11(6)

Human bone marrow-derived mesenchymal stem cells (hBMSC) are able to differentiate into cells of connective tissue lineages, including bone and cartilage. They are therefore considered as a promising tool for the treatment of bone degenerative diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031f3fe75bd1301e3bbe9aaffd9fa158
https://pubmed.ncbi.nlm.nih.gov/26254594

Decreased pool of mesenchymal stem cells is associated with altered chemokines serum levels in atrophic nonunion fractures

Autor: Delphine Spruyt, Enrico Bastianelli, Sabrina Rigutto, Myrielle Mathieu, Nadia Stricwant, Valentina Albarani, Valérie Gangji, Marc Jayankura, Ilham Kharroubi, Joanne Rasschaert, Aude Ingels

Publikováno v: Bone. 53(2)

Nonunion fractures can cause severe dysfunction and are often difficult to treat mainly due to a poor understanding of their physiopathology. Although many aspects of impaired fracture healing have been extensively studied, little is known about the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0801631d7c0afd9cde9e81563f4d4d57
https://pubmed.ncbi.nlm.nih.gov/23318974

Cardiac insulin-like growth factor-1 and cyclins gene expression in canine models of ischemic or overpacing cardiomyopathy

Autor: Kathleen Mc Entee, Agnès Mendes Da Costa, Robert Naeije, Ielham Hadad, Myrielle Mathieu, Karim Touihri, Maryam Mahmoudabady

Publikováno v: BMC Cardiovascular Disorders, Vol 9, Iss 1, p 49 (2009)
BMC cardiovascular disorders, 9
BMC Cardiovascular Disorders
Europe PubMed Central

Insulin-like growth factor-1 (IGF-1), transforming growth factor beta (TGFbeta) and cyclins are thought to play a role in myocardial hypertrophic response to insults. We investigated these signaling pathways in canine models of ischemic or overpacing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27df46ac33d7ab8de6bec0d16189a77a
http://www.biomedcentral.com/1471-2261/9/49