Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Myriam Lebourg"'
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:1684-1691
Chondrogenesis of mesenchymal stem cells (MSCs) is known to be regulated by a number of environmental factors, including local oxygen levels. The hypothesis of this study is that the response of MSCs to hypoxia is dependent on the physical and chemic
Autor:
M. Monleón Pradas, Sandra Vidueira, Juan A. Barcia, Leyre Sanchez‐Rojas, Ulises Gómez-Pinedo, Cristina Martínez-Ramos, Myriam Lebourg, Francisco J. Sancho
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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[EN] Repair of central nervous system (CNS) lesions is difficulted by the lack of ability of central axons to regrow, and the blocking by the brain astrocytes to axonal entry. We hypothesized that by using bridges made of porous biomaterial and permi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef766b8103e154f50fd7f2ed51bbe07
https://doi.org/10.1002/jbm.b.34110
https://doi.org/10.1002/jbm.b.34110
Publikováno v:
Polymer Degradation and Stability. 119:121-131
Poly(L-lactic acid)(PLLA)/poly(e-caprolactone)(PCL)/hydroxyapatite(HAp) composites appear as promising materials for healing large bone defects. Highly porous PLLA/PCL scaffolds, 80/20, 20/80 weight ratios, porosity >85%, were prepared by a dual tech
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 103:1249-1257
Background: Cancer research focuses increasingly on cancer stem cell study as those cells are thought to be the root of chemo and radioresistance of the most aggressive cancer types. Nevertheless, two-dimensional (2D) cell culture and even three-dime
Publikováno v:
Biotechnology and Bioengineering. 110:3048-3058
While most of the in vivo extracellular matrices are 3D, most of the in vitro cultures are 2D—where only ventral adhesion is permitted—thus modifying cell behavior as a way to self-adaptation to this unnatural environment. We hypothesize that the
Publikováno v:
Composites Science and Technology
Composites Science and Technology, Elsevier, 2010, 70 (13), pp.1796. ⟨10.1016/j.compscitech.2010.07.017⟩
Composites Science and Technology, Elsevier, 2010, 70 (13), pp.1796. ⟨10.1016/j.compscitech.2010.07.017⟩
International audience; Composites fabricated by biomimetic mineral precipitation on polymeric substrates are of interest for tissue engineering. As biological properties of such mineral layers vary with slight changes in composition, a good physical
Publikováno v:
European Polymer Journal. 44:2207-2218
Porous membranes of polycaprolactone–poly( l -lactic acid) blends were prepared by a freeze-extraction process. This procedure was able to disperse homogeneously both components despite their amorphous phases being immiscible (as proven by the fact
Autor:
J. Suay Antón, F. Hernández Sánchez, R. Sabater i Serra, J. Mas Estelles, Myriam Lebourg, J.L. Gómez Ribelles
Publikováno v:
Journal of Materials Science: Materials in Medicine. 19:2047-2053
Scaffold with controlled porosity constitute a cornerstone in tissue engineering, as a physical support for cell adhesion and growth. In this work, scaffolds of polycaprolactone were synthesized by a modified particle leaching method in order to cont
Publikováno v:
Journal of Visualized Experiments.
Cell culture has been traditionally carried out on bi-dimensional (2D) substrates where cells adhere using ventral receptors to the biomaterial surface. However in vivo, most of the cells are completely surrounded by the extracellular matrix (ECM), r
Publikováno v:
Nanomedicine (London, England). 10(5)
Aim: We introduced sandwich-like culture as a tool to engineer the cellular nanoenvironment by tuning protein presentation and activation of dorsal and ventral receptors. We aim at studying cell migration under more similar conditions to the 3D physi