Methylselenol Produced In Vivo from Methylseleninic Acid or Dimethyl Diselenide Induces Toxic Protein Aggregation in Saccharomyces cerevisiae

Autor: Marc Dauplais, Katarzyna Bierla, Coralie Maizeray, Roxane Lestini, Ryszard Lobinski, Pierre Plateau, Joanna Szpunar, Myriam Lazard

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 5, p 2241 (2021)

Methylselenol (MeSeH) has been suggested to be a critical metabolite for anticancer activity of selenium, although the mechanisms underlying its activity remain to be fully established. The aim of this study was to identify metabolic pathways of MeSe

Externí odkaz: https://doaj.org/article/e698ecdfa5b14fdd91ae176bd646e6b5

Sodium selenide toxicity is mediated by O2-dependent DNA breaks.

Autor: Gérald Peyroche, Cosmin Saveanu, Marc Dauplais, Myriam Lazard, François Beuneu, Laurence Decourty, Christophe Malabat, Alain Jacquier, Sylvain Blanquet, Pierre Plateau

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e36343 (2012)

Hydrogen selenide is a recurrent metabolite of selenium compounds. However, few experiments studied the direct link between this toxic agent and cell death. To address this question, we first screened a systematic collection of Saccharomyces cerevisi

Externí odkaz: https://doaj.org/article/e9c6b80a22464d87a2bdee148b2d7bd3

Estimating the Radiance in Atmosphere-Ocean Systems With Different Atmosphere Models by Discrete Spherical Harmonics Method

Autor: Arantes Fokou, Réné Tchinda, Guillaume Lambou Ymeli, Myriam Lazard, Cun-Hai Wang

Publikováno v: ASME Journal of Heat and Mass Transfer. 145

The radiative transfer in atmosphere-ocean systems with different atmosphere models is evaluated by the discrete spherical harmonics method. Four standard atmosphere models, namely, Tropical, Mid-Latitude Summer, Mid-Latitude Winter, and U.S. Standar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25dcca3c32c41c51364a646cbb34fdaf
https://doi.org/10.1115/1.4062262

Radiative Equilibrium in a Square Cavity Containing a Square Inner Centred Obstacle, Both with Reflecting Surfaces, and an Absorbing-Emitting Medium

Autor: Vital Le Dez, Julien Sorel Djeumegni, Myriam Lazard

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de32153f76312ea729fdd2d48b4eafb0
https://doi.org/10.2139/ssrn.4211062

Exposure to the Methylselenol Precursor Dimethyldiselenide Induces a Reductive Endoplasmic Reticulum Stress in Saccharomyces cerevisiae

Autor: Pierre Plateau, Marc Dauplais, Myriam Lazard, Pierre Mahou

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, MDPI, 2021, 22 (11), pp.5467. ⟨10.3390/ijms22115467⟩
International Journal of Molecular Sciences, Vol 22, Iss 5467, p 5467 (2021)
International Journal of Molecular Sciences, 2021, 22 (11), pp.5467. ⟨10.3390/ijms22115467⟩

Methylselenol (MeSeH) is a major cytotoxic metabolite of selenium, causing apoptosis in cancer cells through mechanisms that remain to be fully established. Previously, we demonstrated that, in Saccharomyces cerevisiae, MeSeH toxicity was mediated by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7de5ae8903881bd4b310d4594bd3ba