Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Myriam Gou-Fabregas"'
Autor:
Ana Garcera, Stefka Mincheva, Myriam Gou-Fabregas, Víctor Caraballo-Miralles, Jerònia Lladó, Joan X. Comella, Rosa M. Soler
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 3, Pp 415-426 (2011)
Spinal muscular atrophy (SMA) is a motoneuron disorder characterized by deletions or specific mutations in the Survival Motor Neuron gene (SMN). SMN is ubiquitously expressed and has a general role in the assembly of small nuclear ribonucleoprotein (
Externí odkaz:
https://doaj.org/article/cca0e6b8c4a44401a071870815f597f3
Autor:
Stefanie Lemmens, Daniela Sommer, Paulien Baeten, Sven Hendrix, Selien Sanchez, Myriam Gou Fabregas, Dearbhaile Dooley
Publikováno v:
Experimental Neurobiology
After spinal cord injury (SCI), monocyte derived macrophages play a detrimental role. Histone deacetylases (HDACs) are central epigenetic regulators of macrophage-polarization. We hypothesized that HDAC3 inhibition suppresses the pro-inflammatory mac
Autor:
Daniela Sommer, Inge Corstjens, Sven Hendrix, Stefanie Lemmens, Stefan Rose-John, Jana Van Broeckhoven, Pia M. Vidal, Selien Sanchez, Myriam Gou-Fabregas, Jeroen F. J. Bogie, Tim Vanmierlo, Dearbhaile Dooley
Publikováno v:
Brain Behavior and Immunity, 80, 129-145. Elsevier Science
A disintegrin and metalloproteinase 17 (ADAM17) is the major sheddase involved in the cleavage of a plethora of cytokines, cytokine receptors and growth factors, thereby playing a substantial role in inflammatory and regenerative processes after cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fedfb4e500328da17ff8fadb665989
http://hdl.handle.net/1942/29076
http://hdl.handle.net/1942/29076
Autor:
Myriam Gou-Fabregas, Daniel Cacabelos, Rosa M. Soler, Nuria Bahi, Omar Ramírez-Núñez, Manuel Portero, Ana Garcera
Publikováno v:
Molecular and Cellular Neuroscience. 61:219-225
Amyotrophic Lateral Sclerosis (ALS), a severe neurodegenerative disease, affects the upper and lower motor neurons in the brain and spinal cord. In some studies, ALS disease progression has been associated with an increase in calcium-dependent degene
Autor:
Rosa M. Soler, Xavier Dolcet, Ana Garcera, Mario Encinas, Stefka Mincheva, Myriam Gou-Fabregas
Publikováno v:
The Journal of Neuroscience. 31:6493-6503
In vivoandin vitromotoneuron survival depends on the support of neurotrophic factors. These factors activate signaling pathways related to cell survival or inactivate proteins involved in neuronal death. In the present work, we analyzed the involveme
Autor:
Joan X. Comella, Marta Llovera, Myriam Gou-Fabregas, Yolanda de Pablo, M. Jose Perez-Garcia, Rosa M. Soler
Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Neurotrophic factors promote motoneuron (MN) survival through increased intracellular calcium (Ca(2+)) and regulation of the phosphatidylinositol (PI) 3-kinase/protein kinase B (PKB) pathway by calmodulin (CaM). Activation of the PI 3-kinase/PKB path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a2865b788075dbdd88820edab1857b
https://hdl.handle.net/10459.1/59314
https://hdl.handle.net/10459.1/59314