Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Myriam Coulet"'
Autor:
Patrick Serrant, Karma C. Fussell, Nicolas Riederer, Hélia Latado, Benoît Schilter, Julie Mollergues, Myriam Coulet, Maricel Marin-Kuan
Publikováno v:
Toxicology in Vitro. 45:359-365
In vitro effect-based reporter assays are applied as biodetection tools designed to address nuclear receptor mediated-modulation. While such assays detect receptor modulating potential, cell viability needs to be addressed, preferably in the same wel
Autor:
Patrick Serrant, Benoît Schilter, Mireille Moser, Claudine Cottet Fontannaz, Julie Mollergues, Harrie Besselink, Myriam Coulet, Fanny Minetto, Hélia Latado, Matthew Tate, Maricel Marin-Kuan, Dominique Piguet
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 59
Nitrogen-containing polycyclic aromatic hydrocarbons (PANHs or azaarenes) are compounds structurally similar to PAHs (carbon substituted by a nitrogen) reported to occur at low levels in food. Although limited, literature may suggest possible higher
Autor:
Shahrzad Tafazoli, Nigel Baldwin, Phoukham Phothirath, Anne Petersen, Myriam Coulet, Johanna Lang, Anne Constable, Trung D. Vo
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 87
The potential toxicity of two savory food ingredients produced by fermentation of enzymatically hydrolyzed corn starch (Savory Base 100 and Savory Base 200) was evaluated individually in a bacterial reverse mutation assay, an in vitro mammalian cell
Autor:
Lutz Edler, Gary M. Williams, Andy Hart, Alan R. Boobis, B. Smith, Myriam Coulet, Philip Carthew, Peter Greaves
Publikováno v:
Food and Chemical Toxicology. 70:264-289
This article addresses a number of concepts related to the selection and modelling of carcinogenicity data for the calculation of a Margin of Exposure. It follows up on the recommendations put forward by the International Life Sciences Institute - Eu
Publikováno v:
Regulatory Toxicology and Pharmacology. 68:59-69
In order to match the composition of human breast milk more closely, it is now possible to supplement commercial infant formula (IF) with synthesised oligosaccharides that are chemically identical to human milk oligosaccharides. The safety data gener
Publikováno v:
Food and Chemical Toxicology. 62:528-537
Lacto-N-neotetraose (LNnT) is a tetrasaccharide naturally occurring in human breast milk, but not in cow's milk. The safety data generated on a potential new LNnT ingredient produced by chemical synthesis is presented. Standard in vitro genotoxicity
Autor:
Hélia Latado, Matthew Tate, Mireille Moser, Benoît Schilter, Julie Mollergues, Claudine Bezençon, Myriam Coulet, Maricel Marin-Kuan, Dominique Piguet, Harrie Besselink, Patrick Serrant
Publikováno v:
Toxicology Letters. 280:S268-S269
Autor:
K. Mace, Pierre Galtier, Michel Alvinerie, A. M. A. Pfeifer, G. Larrieu, Myriam Coulet, Mauro Dacasto, Jean-François Sutra, C. Eeckhoutte
Publikováno v:
Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 1998, pp.225-235
Fundamental and Clinical Pharmacology, Wiley, 1998, pp.225-235
This report characterized one of the major cytochrome P450 isozyme involved in thiabendazole metabolism. This study was undertaken by using both cultured rabbit hepatocytes treated or not with drugs known to specifically induced various cytochromes P
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 48
Sudan I is generally considered mutagenic based on various in vitro and in vivo tests and is carcinogenic in the rat. Dose-response modelling of the data for hepatocellular adenomas in male rats gave a BMDL(10) of 7.3mg/kg-bw/day. Sudan I is an unaut
Publikováno v:
ChemInform. 40
The chronic toxicity is fundamental for toxicological risk assessment, but its correlation with the chemical structures has been studied only little. This is partly due to the complexity of such an experimental test that embraces a plethora of differ