Metformin in women with type 2 diabetes in pregnancy (MiTy): a multicentre, international, randomised, placebo-controlled trial

Autor: Sora Ludwig, Melissa Deans, Stacey Lacerte, Catherine Young, Kellie E. Murphy, J. Johanna Sanchez, Peter Subrt, David Thompson, Kayla Schutt, George Carson, Bernard Zinman, Thomas Ransom, Melanie Robinson, Minnie Parsons, Shirley Beauchamp, Darlene Baxendale, Afshan Zahedi, Richard Phillips, Natasha Garfield, Paul Karanicolas, Jason Kong, Adriana Breen, Agnieszka Barts, Vincent Wong, Elizabeth Asztalos, Jon Barrett, Heather Belanger, Bonnie Stone-Hope, Josee Champagne, Julie Lambert, Myriam Bouchard, Michele Mahone, Sharon Thompson, Carolyn Oldford, David McIntyre, Dynika St Omer, Raquel Dias, Martin D'Amours, Josephine Laurie, Leila MacBean, Nashwah Taha, Veronica Gale, Wayne Andrews, Heidi Virtanen, Judy Brandt, Heidi Hirsimaki, Mauricio Marin, Gail Klein, Heather Clark, Bernadette Rowe, Joel Ray, Julie Lee, Mark McLean, Siobhan Tobin, Anne-Marie Powell, Janine Malcolm, Paul J. Karanicolas, Claire Gougeon, Leanne De Souza, Elaine O'Shea, Cathy Robb, Marci Turner, Jill Newstead-Angel, Sharon Young, Joan Crane, Leslie Berndl, Simona Meier, Valérie-Ève Julien, Maureen Mattick, Lorraine L. Lipscombe, Simon Tian, Lisa Vizza, Karen Coles, Ken Lim, Razita Singh, Abhay Lodha, George Tomlinson, Shari Segal, Marie-Christine Dubé, Barbara Cleave, Colette Favreau, Howard Berger, Florence Weber, Shital Gandhi, Carol Fergusson, Anthony Armson, Sarah Kwong, Margaret Watson, Michele Strom, George I Fantus, Steve Chalifoux, Ilana Halperin, Anne E. Cook, J Johanna Sanchez, Jillian Coolen, Marnie Nerdal-Bussell, Cheryl Verhesen, Debbie Fong, Marie-Josee Bedard, Susan Hendon, Allison Sigmund, Sara Meltzer, Madalena Neculau, Renee Kludas, Annie Castonguay, Jennifer M. Yamamoto, Bekki Cavallaro, Rshmi Khurana, Effie Viguiliouk, Camille Lambert, Helen R. Murphy, Cora Fanning, Grace Lee, Robyn L. Houlden, Laurie Slater, Eileen K. Hutton, Lorraine Cauchi, Janet Slaunwhite, Prem Lata, Lois E. Donovan, Debbie McGuire, Carolyn Bergan, Aarthi Kamath, Louise Bastien, Sarah Capes, Kathryn Mangoff, Rohit Rajagopal, Anne Tremellen, David Miller, Sophie Perreault, Louise Rheaume, Sherri Pockett, Sophie Leblanc, Christyne Allen, Wenjun Nie, Amira El-Messidi, Edmond A. Ryan, Denice S Feig, Christine Orr, Vinolia ArthurHayward, H. David McIntyre, Ariane Godbout, Denice S. Feig, Jennifer Sloan, Heather Rylance, Simon Yu Tian, Hamish Russell, Sylvie Daigle, Suzanne Williams, Diane Donat, Krista Rideout, Vivian Zhou, Carol Joyce, Krystyna Szwiega, Allan Karovitch, Marie-Claude Bourbonniere, Helen Barrett, Amir Hanna, Tina Kader, Claudia Bishop, I. George Fantus, Ruth McManus, Stephanie Cooper, Jennifer Klinke, Bi Lan Wo, Keitha McMurray, Brenda Galway, S. John Weisnagel, Erin Keely, Jodie Nema, Joyce Mitchell, Hélène Long, Frances Maguire, Alice Cheng, Munira Sultana, Melin Peng, Jane Fox, Evelyne Rey, Francina Carr, Galina Smushkin, Tammy McNab, Maria Wolfs, Helen G. Liley, David Simmons

Publikováno v: The lancet. Diabetesendocrinology. 8(10)

Summary Background Although metformin is increasingly being used in women with type 2 diabetes during pregnancy, little data exist on the benefits and harms of metformin use on pregnancy outcomes in these women. We aimed to investigate the effects of

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https://pubmed.ncbi.nlm.nih.gov/33065062