Sir3 mediates long-range chromosome interactions in budding yeast

Autor: Romain Koszul, Angela Taddei, Luciana Lazar-Stefanita, Antoine Hocher, Myriam Ruault, Vittore F. Scolari, Isabelle Loïodice

Publikováno v: Genome Research
Genome Research, Cold Spring Harbor Laboratory Press, 2021, 31 (3), pp.411-425. ⟨10.1101/gr.267872.120⟩
Genome Research, 2021, 31 (3), pp.411-425. ⟨10.1101/gr.267872.120⟩
Genome Res

Physical contacts between distant loci contribute to regulate genome function. However, the molecular mechanisms responsible for settling and maintaining such interactions remain poorly understood. Here, we investigate the well-conserved interactions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67054d04d3dd938b7be5b6df0c10e56b
https://hal.sorbonne-universite.fr/hal-03169421

Expanding heterochromatin reveals discrete subtelomeric domains delimited by chromatin landscape transitions

Autor: Petra Kaferle, Angela Taddei, Marc Descrimes, Antoine Hocher, Myriam Ruault, Antonin Morillon, Mickael Garnier

Publikováno v: Genome Research
Genome Research, Cold Spring Harbor Laboratory Press, 2018, 28 (12), pp.1867-1881. ⟨10.1101/gr.236554.118⟩

The eukaryotic genome is divided into chromosomal domains of distinct gene activities. Transcriptionally silent chromatin chromatin is found in subtelomeric regions leading to telomeric position effect (TPE) in yeast, fly and man. Silent chromatin ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5446b12c14cb1aebc6bd0c3f8c400150
https://hal.sorbonne-universite.fr/hal-01977753

Spatial telomere organization and clustering in yeast Saccharomyces cerevisiae nucleus is generated by a random dynamics of aggregation–dissociation

Autor: Myriam Ruault, David Holcman, Nathanaël Hozé, Angela Taddei, Carlo Amoruso

Publikováno v: Molecular Biology of the Cell

The 32 telomeres of budding yeast form clusters, yet whether clusters are due to random localization or telomeric interactions is unclear. Data from live-cell imaging are compared with a biophysical model of telomere dynamics. Direct molecular intera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcb8bfa7346319013c5297e1176c46a
https://doi.org/10.1091/mbc.e13-01-0031

Spatial reorganization of telomeres in long-lived quiescent cells

Autor: Angela Taddei, Antoine Hocher, Romain Koszul, Julien Mozziconacci, Martial Marbouty, Axel Cournac, Cyrille Billaudeau, Myriam Ruault, Micol Guidi, Isabelle Loïodice

Publikováno v: Genome Biology
Genome Biology, 2015, 16 (1), pp.206. ⟨10.1186/s13059-015-0766-2⟩
Genome Biology, BioMed Central, 2015, 16 (1), pp.206. ⟨10.1186/s13059-015-0766-2⟩

Background The spatiotemporal behavior of chromatin is an important control mechanism of genomic function. Studies in Saccharomyces cerevisiae have broadly contributed to demonstrate the functional importance of nuclear organization. Although in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4673ea9b10663e88a518524cdbee5d30
https://hal.sorbonne-universite.fr/hal-01206018

Expression of Subtelomeric lncRNAs Links Telomeres Dynamics to RNA Decay in

Autor: Marta, Kwapisz, Myriam, Ruault, Erwin, van Dijk, Stephanie, Gourvennec, Marc, Descrimes, Angela, Taddei, Antonin, Morillon

Publikováno v: Non-Coding RNA

Long non-coding RNAs (lncRNAs) have been shown to regulate gene expression, chromatin domains and chromosome stability in eukaryotic cells. Recent observations have reported the existence of telomeric repeats containing long ncRNAs – TERRA in mamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::947d462b020758e2a1c04192992215d9
https://pubmed.ncbi.nlm.nih.gov/29861418