Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Myriam, Polette"'
Autor:
Laure M.G. Petit, Randa Belgacemi, Julien Ancel, Lynda Saber Cherif, Myriam Polette, Jeanne-Marie Perotin, Nathalie Spassky, Charles Pilette, Denise Al Alam, Gaëtan Deslée, Valérian Dormoy
Publikováno v:
European Respiratory Review, Vol 32, Iss 170 (2023)
Cilia are organelles emanating from the cell surface, consisting of an axoneme of microtubules that extends from a basal body derived from the centrioles. They are either isolated and nonmotile (primary cilia), or grouped and motile (motile cilia). C
Externí odkaz:
https://doaj.org/article/e0fbf611df534e4fb204be9a76171269
Autor:
Julien Ancel, Valérian Dormoy, Béatrice Nawrocki Raby, Véronique Dalstein, Anne Durlach, Maxime Dewolf, Christine Gilles, Myriam Polette, Gaëtan Deslée
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Lung cancer remains the first cause of cancer-related death despite many therapeutic innovations, including immune checkpoint inhibitors (ICI). ICI are now well used in daily practice at late metastatic stages and locally advanced stages after a chem
Externí odkaz:
https://doaj.org/article/bc95270bed864c468dac1936841ff690
Autor:
Emma Loeffler, Julien Ancel, Véronique Dalstein, Gaëtan Deslée, Myriam Polette, Béatrice Nawrocki-Raby
Publikováno v:
Life, Vol 14, Iss 1, p 64 (2023)
Lung cancer stands as the first cause of death by cancer in the world. Despite the improvement in patients’ outcomes in the past decades through the development of personalized medicine approaches, a substantial portion of patients remains ineligib
Externí odkaz:
https://doaj.org/article/50d63507da0847bc9f318f5e0d2025c1
Autor:
Audrey Brisebarre, Julien Ancel, Théophile Ponchel, Emma Loeffler, Adeline Germain, Véronique Dalstein, Valérian Dormoy, Anne Durlach, Gonzague Delepine, Gaëtan Deslée, Myriam Polette, Béatrice Nawrocki-Raby
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionIn recent decades, the development of immunotherapy and targeted therapies has considerably improved the outcome of non-small cell lung cancer (NSCLC) patients. Despite these impressive clinical benefits, new biomarkers are needed for an
Externí odkaz:
https://doaj.org/article/27e2eb5b197d4f809774842db824e225
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-7 (2021)
Abstract The pathophysiology of chronic obstructive pulmonary disease (COPD) relies on airway remodelling and inflammation. Alterations of mucociliary clearance are a major hallmark of COPD caused by structural and functional cilia abnormalities. Usi
Externí odkaz:
https://doaj.org/article/d006668c66aa4c37b9fb91f60070b1ab
Autor:
Julien Ancel, Randa Belgacemi, Jeanne-Marie Perotin, Zania Diabasana, Sandra Dury, Maxime Dewolf, Arnaud Bonnomet, Nathalie Lalun, Philippe Birembaut, Myriam Polette, Gaëtan Deslée, Valérian Dormoy
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background The hedgehog (HH) pathway has been associated with chronic obstructive pulmonary disease (COPD) in genome-wide association studies and recent studies suggest that HH signalling could be altered in COPD. We therefore used minimally
Externí odkaz:
https://doaj.org/article/d3c898ea7f4444deb136da622706d85f
Autor:
Déborah Neyrinck-Leglantier, Julien Lesage, Silvia Blacher, Arnaud Bonnomet, Walter Hunziker, Agnès Noël, Valérian Dormoy, Béatrice Nawrocki-Raby, Christine Gilles, Myriam Polette
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Delocalization of zonula occludens-1 (ZO-1) from tight junctions plays a substantial role in epithelial cell plasticity observed during tumor progression. In vitro, we reported an impact of ZO-1 cyto-nuclear content in modulating the secretion of sev
Externí odkaz:
https://doaj.org/article/9d1943e2c9f4411984740c92b60c8388
Autor:
Lynda Saber Cherif, Zania Diabasana, Jeanne-Marie Perotin, Julien Ancel, Laure M. G. Petit, Maëva A. Devilliers, Arnaud Bonnomet, Nathalie Lalun, Gonzague Delepine, Uwe Maskos, Philippe Gosset, Myriam Polette, Anaëlle Muggeo, Thomas Guillard, Gaëtan Deslée, Valérian Dormoy
Publikováno v:
Cells, Vol 11, Iss 19, p 2937 (2022)
Genome-wide association studies unveiled the associations between the single nucleotide polymorphism rs16969968 of CHRNA5, encoding the nicotinic acetylcholine receptor alpha5 subunit (α5SNP), and nicotine addiction, cancer, and COPD independently.
Externí odkaz:
https://doaj.org/article/d01262c16f684018844cccbc47fd956d
Autor:
Adeline Germain, Jeanne-Marie Perotin, Gonzague Delepine, Myriam Polette, Gaëtan Deslée, Valérian Dormoy
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1714 (2022)
The remodelling of the airways is a hallmark of chronic obstructive pulmonary disease, but it is highly heterogeneous and erratically distributed in the airways. To assess the genetic print of remodelling in chronic obstructive pulmonary disease (COP
Externí odkaz:
https://doaj.org/article/d20311cfa3fa48f0ab53c3bc11b985f2
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 658 (2022)
Hyaluronic acid (HA) is a major component of the extracellular matrix. It is synthesized by hyaluronan synthases (HAS) into high-molecular-weight chains (HMW-HA) that exhibit anti-inflammatory and immunomodulatory functions. In damaged, infected, and
Externí odkaz:
https://doaj.org/article/b9543bed48d44f33b1f71347ef136e9a