Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Mypinder S, Sekhon"'
Autor:
Breanna K. Nelson, Lea N. Farah, Ava Grier, Wayne Su, Johnson Chen, Vesna Sossi, Mypinder S. Sekhon, A. Jon Stoessl, Cheryl Wellington, William G. Honer, Donna Lang, Noah D. Silverberg, William J. Panenka
Publikováno v:
NeuroImage, Vol 300, Iss , Pp 120859- (2024)
Background: The pathophysiology of protracted symptoms after COVID-19 is unclear. This study aimed to determine if long-COVID is associated with differences in baseline characteristics, markers of white matter diffusivity in the brain, and lower scor
Externí odkaz:
https://doaj.org/article/a4447bd59eac4f668b6311c649a267a5
Publikováno v:
Resuscitation Plus, Vol 17, Iss , Pp 100556- (2024)
Introduction: Post-cardiac arrest brain injury (PCABI) is the primary determinant of clinical outcomes for patients who achieve return of spontaneous circulation after cardiac arrest (CA). There are limited neuroprotective therapies available to miti
Externí odkaz:
https://doaj.org/article/c6f2a3a24abd4ee38cbecec27d205e96
Autor:
Nikunj A. Patel, MD, Harvir S. Bhattal, BSc, Donald E. Griesdale, MD, MPH, Ryan L. Hoiland, PhD, Mypinder S. Sekhon, MD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 2, p e1049 (2024)
OBJECTIVES:. Near-infrared spectroscopy (NIRS) is used in critical care settings to measure regional cerebral tissue oxygenation (rSo2). However, the accuracy of such measurements has been questioned in darker-skinned individuals due to the confoundi
Externí odkaz:
https://doaj.org/article/b7b26953af4d4bc38c0191e3297024eb
Autor:
Melina Messing, Mypinder S. Sekhon, Michael R. Hughes, Sophie Stukas, Ryan L. Hoiland, Jennifer Cooper, Nyra Ahmed, Mark S. Hamer, Yicong Li, Samuel B. Shin, Lin Wei Tung, Cheryl L. Wellington, Don D. Sin, Kevin B. Leslie, Kelly M. McNagny
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The COVID-19 pandemic continues to challenge the capacities of hospital ICUs which currently lack the ability to identify prospectively those patients who may require extended management. In this study of 90 ICU COVID-19 patients, we evaluated serum
Externí odkaz:
https://doaj.org/article/e664c34af33143408e6843b6957ebf8c
Autor:
Sophie Stukas, George Goshua, Angus Kinkade, Rebecca Grey, Gregory Mah, Catherine M. Biggs, Shahin Jamal, Sonny Thiara, Tim T.Y. Lau, Jolanta Piszczek, Nilu Partovi, David D Sweet, Agnes Y.Y. Lee, Cheryl L. Wellington, Mypinder S. Sekhon, Luke Y.C. Chen
Publikováno v:
The Lancet Regional Health. Americas, Vol 11, Iss , Pp 100228- (2022)
Summary: Background: Interleukin-6 inhibitors reduce mortality in severe COVID-19. British Columbia began using tocilizumab 8 mg/kg (maximum 800 mg) in January 2021 in critically ill patients with COVID-19, but due to drug shortages, decreased dosing
Externí odkaz:
https://doaj.org/article/5fe720dec2324ee885ff324e824e3cb4
Autor:
Sam D. Shemie, Lindsay C. Wilson, Laura Hornby, John Basmaji, Andrew J. Baker, Cécile M. Bensimon, Jennifer A. Chandler, Michaël Chassé, Rosanne Dawson, Sonny Dhanani, Owen T. Mooney, Aimee J. Sarti, Christy Simpson, Jeanne Teitelbaum, Sylvia Torrance, J. Gordon Boyd, Joanne Brennan, Heather Brewster, Robert Carignan, Kirk J. Dawe, Christopher J. Doig, Kennedy Elliott-Pohl, Teneille E. Gofton, Michael Hartwick, Andrew Healey, Kimia Honarmand, Karen Hornby, George Isac, Aly Kanji, Joann Kawchuk, Jennifer A. Klowak, Andreas H. Kramer, Julie Kromm, Allana E. LeBlanc, Katarina Lee-Ameduri, Laurie A. Lee, Murdoch Leeies, Ariane Lewis, Alex Manara, Shauna Matheson, Nicole K. A. McKinnon, Nicholas Murphy, Joel Neves Briard, Thaddeus M. Pope, Mypinder S. Sekhon, Jai Jai S. Shanker, Gurmeet Singh, Jeffrey Singh, Marat Slessarev, Karim Soliman, Stephanie Sutherland, Matthew J. Weiss, Randi Zlotnik Shaul, Lionel S. Zuckier, David J. Zorko, Bram Rochwerg
Publikováno v:
Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 70:483-557
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eea4c3c044f19048699729f16104d040
https://doi.org/10.1007/s12630-023-02431-4
https://doi.org/10.1007/s12630-023-02431-4
Autor:
Luke Y.C. Chen, Catherine M. Biggs, Shahin Jamal, Sophie Stukas, Cheryl L. Wellington, Mypinder S. Sekhon
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100269- (2021)
Summary: Data suggest that interleukin (IL)-6 blockade could reduce mortality in severe COVID-19, yet IL-6 is only modestly elevated in most patients. Chen et al. describe the role of soluble interleukin-6 receptor (sIL-6R) in IL-6 trans-signaling an
Externí odkaz:
https://doaj.org/article/a24a15f5b1734782bc15e9145aadade4
Autor:
Ryan Leo Hoiland, PhD, Donald E. Griesdale, MD, MPH, Peter Gooderham, MD, Mypinder S. Sekhon, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 5, p e0396 (2021)
Objectives:. We aimed to characterize the cerebrovascular physiology of cerebral fat embolism using invasive multimodal neuromonitoring. Data Sources:. ICU, Vancouver General Hospital, Vancouver, BC, Canada. Study Selection:. Case report. Data Extrac
Externí odkaz:
https://doaj.org/article/bb0295a80a844d7db83e45a7f1fe1ee2
Autor:
Jacob L. Stubbs, Katherine E. Green, Noah D. Silverberg, Andrew Howard, Amrit K. Dhariwal, Jeffrey R. Brubacher, Naisan Garraway, Manraj K. S. Heran, Mypinder S. Sekhon, Angela Aquino, Victoria Purcell, James S. Hutchison, Ivan J. Torres, William J. Panenka
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Somatization may contribute to persistent symptoms after mild traumatic brain injury (mTBI). In two independently-recruited study samples, we characterized the extent to which symptoms atypical of mTBI but typical for patients suffering from somatiza
Externí odkaz:
https://doaj.org/article/363654efe35d45e9bacf33c252dbbf34
Publikováno v:
Critical Care, Vol 21, Iss 1, Pp 1-5 (2017)
Abstract Secondary injury is a major determinant of outcome in hypoxic ischemic brain injury (HIBI) after cardiac arrest and may be mitigated by optimizing cerebral oxygen delivery (CDO2). CDO2 is determined by cerebral blood flow (CBF), which is dep
Externí odkaz:
https://doaj.org/article/e9b642d390ec45e2bac3315b1e7934a6