Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Myoungki Baek"'
Autor:
Sumin Lim, Seulgi Choi, Ju-Kyung Lee, Eunhyun Choi, Sungwon Lee, Kwangwoo Chun, Myoungki Baek, Jiyeon Park, Jihyun Kim, Areum Kang, Younghoon Kim, Namkyoung Kim, Byoungchul Cho, Taebo Sim, Koo Lee
Publikováno v:
Cancer Research. 83:4006-4006
Targeting mutated EGFR is a clinically validated approach for tackling non-small cell lung cancer (NSCLC). Approximately 20% of patients with advanced NSCLC harbor an EGFR mutation. Osimertinib is a 3rd-generation oral EGFR-TKI targeting the EGFR sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15f72a6186ee7bbaf4d96c8c17ef062d
https://doi.org/10.1158/1538-7445.am2023-4006
https://doi.org/10.1158/1538-7445.am2023-4006
Autor:
Doo-Young Kim, Daehoon Kim, Chun Hwa Kim, Myoungki Baek, Kyu Hwan Lee, Seung Jun Kang, Hyo Sun Choi, Hankyu Lee
Publikováno v:
Diabetes. 69
Glucagon-like peptide-1 (GLP-1) mediates antidiabetogenic effects through the GLP-1 receptor (GLP-1R), which is targeted for the treatment of type 2 diabetes. Currently, GLP-1R agonists comprise a growing class of agents that deliver unprecedented ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cf7aac65161a4083ab9faf7bbd06fe0
https://doi.org/10.2337/db20-939-p
https://doi.org/10.2337/db20-939-p
Publikováno v:
Diabetes. 69
Previously, HD-6277 was reported about its safety and tolerability in healthy volunteers both in single ascending doses (SAD) and multiple ascending doses (MAD) study over all doses under fasting conditions. Based on these results, two doses with 25m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d19de0c449c6f5a4c9416f1da74c322e
https://doi.org/10.2337/db20-1089-p
https://doi.org/10.2337/db20-1089-p
Publikováno v:
Archives of Pharmacal Research. 34:2059-2064
The study aimed to characterize the pharmacokinetics of lacosamide, a new antiepileptic drug, in rats after intravenous and oral administration at doses of 1, 3, 10, and 30 mg/kg. Moreover, brain distribution and plasma protein binding were estimated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab1b4a838c91aa1be2949f797110bcf
https://doi.org/10.1007/s12272-011-1208-7
https://doi.org/10.1007/s12272-011-1208-7
Publikováno v:
Biomedical Chromatography. 25:1389-1394
A liquid chromatography–tandem mass spectrometric (LC/MS/MS) method was developed for the determination of an atypical antipsychotic drug, lurasidone, in rat plasma. The method involves the addition of acetonitrile and ziprasidone (internal standar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55d4a99ccec9bb0f6395c8c3f42ae168
https://doi.org/10.1002/bmc.1625
https://doi.org/10.1002/bmc.1625
Publikováno v:
European Journal of Pharmaceutical Sciences. 28:243-248
The distribution kinetics of the highly lipophilic antiarrhythmic agent amiodarone is not well understood. The purpose of the present investigation was to develop a pharmacokinetic-pharmacodynamic (PK/PD) model to describe cardiac uptake and the nega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effd10e916bbb1d47dee8cbf880384bc
https://doi.org/10.1016/j.ejps.2006.02.007
https://doi.org/10.1016/j.ejps.2006.02.007
Autor:
Myoungki Baek, Michael Weiss
Publikováno v:
European Journal of Pharmacology. 514:43-51
The mechanisms by which endotoxemia affects myocardial contractility and responsiveness to inotropic drugs are not well understood. We examined the positive inotropic effect of digoxin in single-pass Langendorff-perfused hearts from rats after in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74232272c9674a33bbab721a0d686a5
https://doi.org/10.1016/j.ejphar.2005.03.020
https://doi.org/10.1016/j.ejphar.2005.03.020
Autor:
Michael Weiss, Myoungki Baek
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 313:731-739
Cardiac hypertrophy in rats induces a down-regulation of Na(+),K(+)-ATPase alpha(2) isoform, although its functional consequences are poorly understood. Using a mathematical modeling approach that allows differentiation between effects elicited at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe528e1c6dafb25be178b971844ff210
https://doi.org/10.1124/jpet.104.078345
https://doi.org/10.1124/jpet.104.078345
Autor:
Soo-Jin Kim, Dong-Soo Shin, Myoungki Baek, Dong-Jin Ha, Sang-Kil Lee, Hongsik Moon, Tae-Sung Koo
Publikováno v:
Biomedical Chromatography.
A rapid, simple and sensitive liquid chromatography–tandem mass spectrometry (LC/MS/MS) was developed for the determination of an antiepileptic drug, lacosamide, in rat plasma. The method involves the addition of acetonitrile and internal standard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b304f08f6657024f0fdc6afc5618062d
https://doi.org/10.1002/bmc.1668
https://doi.org/10.1002/bmc.1668
Autor:
Soo-Jin, Kim, Tae-Sung, Koo, Dong-Jin, Ha, Myoungki, Baek, Sang-Kil, Lee, Dong-Soo, Shin, Hongsik, Moon
Publikováno v:
Biomedical chromatography : BMC. 26(3)
A rapid, simple and sensitive liquid chromatography-tandem mass spectrometry (LC/MS/MS) was developed for the determination of an antiepileptic drug, lacosamide, in rat plasma. The method involves the addition of acetonitrile and internal standard so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3174e8f7e67d605ec4f52ab34e654faf
https://pubmed.ncbi.nlm.nih.gov/21735462
https://pubmed.ncbi.nlm.nih.gov/21735462