Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Myoung-hee KANG"'
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 12, Pp 6006-6014 (2022)
Frequent mutation of APC (90%) in advanced colorectal cancer (CRC) results in the simultaneous activation of Wnt/β-catenin and AKT signaling pathways, and the current therapeutic limitations of the AKT inhibitors for treating CRC patients are nuclea
Externí odkaz:
https://doaj.org/article/ae62cc3d6d2c4b8a90f9af1b5fd04e0c
Publikováno v:
Organoid, Vol 3 (2023)
Background Mutations of adenomatous polyposis coli (APC) and KRAS play essential roles in the development of colorectal cancer (CRC) by forming an abnormal colon morphology. Despite intensive efforts to discover therapeutic strategies to re-transform
Externí odkaz:
https://doaj.org/article/45bebb2f52754c8a9fb4162b80f351e3
Autor:
Dong Ha Kim, Hyojeong Park, Yun Jung Choi, Myoung-Hee Kang, Tae-Keun Kim, Chan-Gi Pack, Chang-Min Choi, Jae Cheol Lee, Jin Kyung Rho
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-10 (2021)
Abstract Tumor-derived exosomes (TEXs) contain enriched miRNAs, and exosomal miRNAs can affect tumor growth, including cell proliferation, metastasis, and drug resistance through cell-to-cell communication. We investigated the role of exosomal miR-12
Externí odkaz:
https://doaj.org/article/dca042ad4e0344bb8fd7320f676e8ec6
Autor:
Arum Park, Hyojung Park, Jisun Yoon, Dayeon Kang, Myoung-Hee Kang, Y-Y Park, Nayoung Suh, Jinho Yu
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background Atopic dermatitis (AD) is a chronic and relapsing inflammatory skin disease. Great efforts have been recently made to treat AD using mesenchymal stem cells (MSCs), which have immunomodulatory functions. However, the immunomodulato
Externí odkaz:
https://doaj.org/article/406db0a626804f249dfc3a9789dcd900
Autor:
Yi-deun Jung, Seul-Ki Park, Dayeon Kang, Supyong Hwang, Myoung-Hee Kang, Seung-Woo Hong, Jai-Hee Moon, Jae-Sik Shin, Dong-Hoon Jin, Dalsan You, Joo-Yong Lee, Yun-Yong Park, Jung Jin Hwang, Choung Soo Kim, Nayoung Suh
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101716- (2020)
The use of human mesenchymal stem cells (hMSCs) in clinical applications requires large-scale cell expansion prior to administration. However, the prolonged culture of hMSCs results in cellular senescence, impairing their proliferation and therapeuti
Externí odkaz:
https://doaj.org/article/d7bdcda2461b48568d4becadd31fe34a
Autor:
Myoung-Hee Kang, Hyunji Choi, Masanobu Oshima, Jae-Ho Cheong, Seokho Kim, Jung Hoon Lee, Young Soo Park, Hueng-Sik Choi, Mi-Na Kweon, Chan-Gi Pack, Ju-Seog Lee, Gordon B. Mills, Seung-Jae Myung, Yun-Yong Park
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Very little is known regarding the molecular mechanisms involved in gastric cancer development. Here the authors show estrogen-related receptor gamma (ESRRG) is a tumor suppressor in gastric cancer and suggest the mechanism of this tumor suppression
Externí odkaz:
https://doaj.org/article/973b51c8851d4d10916c207ff982e196
Autor:
Wonjun Ji, Yun Jung Choi, Myoung-Hee Kang, Ki Jung Sung, Dong Ha Kim, Sangyong Jung, Chang-Min Choi, Jae Cheol Lee, Jin Kyung Rho
Publikováno v:
Cells, Vol 9, Iss 12, p 2596 (2020)
Epithelial to mesenchymal transition (EMT) is associated with resistance during EGFR tyrosine kinase inhibitor (EGFR-TKI) therapy. Here, we investigated whether EMT is associated with acquired resistance to 3rd generation EGFR-TKIs, and we explored t
Externí odkaz:
https://doaj.org/article/e022beb02ede40ada3485a4867f8e222
Autor:
Sanghee Kang, Bo Ram Kim, Myoung-Hee Kang, Dae-Young Kim, Dae-Hee Lee, Sang Cheul Oh, Byung Wook Min, Jun Won Um
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205449 (2018)
Metformin, a first-line drug used to treat type 2 diabetes, has also been shown to have anticancer effects against a variety of malignancies, including colorectal cancer. Although inhibition of the mTOR pathway is known to be the most important mecha
Externí odkaz:
https://doaj.org/article/4b93cc70bb084faaaffff2b060a6442c
Author Correction: Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer
Autor:
Myoung-Hee Kang, Hyunji Choi, Masanobu Oshima, Jae-Ho Cheong, Seokho Kim, Jung Hoon Lee, Young Soo Park, Hueng-Sik Choi, Mi-Na Kweon, Chan-Gi Pack, Ju-Seog Lee, Gordon B. Mills, Seung-Jae Myung, Yun-Yong Park
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
The original version of this Article contained errors in Figs. 4, 5, and 6. In Fig. 4d, the x-axis label incorrectly read ‘blank, +, blank, +’, and in Fig. 5e, the bars of the second graph from the left were coloured blue-orange-blue-orange. Both
Externí odkaz:
https://doaj.org/article/14f3ce7a03a6497e82d3479757c7c5f4
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Systemic inflammation and cachexia are associated with adverse clinical outcomes in diffuse large B-cell lymphoma (DLBCL). The Geriatric Nutritional Risk Index (GNRI) is one of the main parameters used to assess these conditions,
Externí odkaz:
https://doaj.org/article/e44f3012eee1478da633f10b6a37de6c