Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Myoung-Soon Park"'
Autor:
Myoung-Soon Park, Hyun-Ju Park, Young Jae An, Joon Hun Choi, Geunyoung Cha, Hwa Jeong Lee, So-Jung Park, Purushottam M. Dewang, Dae-Kee Kim
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 702-712 (2020)
A series of 2,4-disubstituted-5-(6-alkylpyridin-2-yl)-1H-imidazoles, 7a–c, 11a–h, and 16a–h has been synthesised and evaluated for their ALK5 inhibitory activity in an enzyme assay and in a cell-based luciferase reporter assay. Incorporation of
Externí odkaz:
https://doaj.org/article/2fc2b50248544d77ab13b36418189d1c
Autor:
Hong-Sig Sin, Si-Ho Park, Hye-Sook Han, Soo-Jong Um, Youn-Ja Kwon, Young-Soy Rho, Myoung-Soon Park
Publikováno v:
Chemical and Pharmaceutical Bulletin. 52:501-506
Retinoic acid and its amide derivative, N-(4-hydroxyphenyl)retinamide (4-HPR), have been proposed as chemopreventative and chemotherapeutic agents. However, their low cytotoxic activity and water solubility limit their clinical use. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0b55935b9fc5f5ae1faa5797849869
https://doi.org/10.1248/cpb.52.501
https://doi.org/10.1248/cpb.52.501
Publikováno v:
Bioorganic & Medicinal Chemistry. 11:5345-5352
To synthesize glycyrrhetinic acid (GA) derivatives (3, 4, 5, 10, 13, 14, 15, and 16), we first removed the ketonic group in the C-11 position, and the carboxylic function at the C-30 position was kept intact, reduced to an alcohol, or transformed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718615dd49d9990d8fccd48217b44429
https://doi.org/10.1016/j.bmc.2003.09.046
https://doi.org/10.1016/j.bmc.2003.09.046
Publikováno v:
Tetrahedron. 59:2921-2928
Three regioisomers of a naturally occurring lysophosphatidylcholine were chemically synthesized from glycerol. The phosphocholine moiety of the molecule was introduced by sequentially reacting with ethylene chlorophosphite, bromine, water, and trimet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d322be11e85797fe3431f51f1ea66185
https://doi.org/10.1016/s0040-4020(03)00282-5
https://doi.org/10.1016/s0040-4020(03)00282-5
Publikováno v:
Pediatric Cardiology. 24:588-590
We report a fetus with an unusual combination of a narrow ductus arteriosus (DA) and foramen ovale. A pregnant mother was referred at 26 weeks of gestation for fetal pericardial effusion. Fetal echocardiography showed pericardial effusion, right atri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3acb9e6c29f7c739a71b2331437fbd0
https://doi.org/10.1007/s00246-003-0511-6
https://doi.org/10.1007/s00246-003-0511-6
Publikováno v:
Experimentalmolecular medicine. 37(2)
We purified phytoestrogens from Pueraria root (Pueraria mirifica from Thailand and Pueraria lobata from Korea), which is used as a rejuvenating folk medicine in Thailand and China. Dried, powdered plant material was extracted with 100% ethanol and fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42aae6e1e697d8e341c7e04d8b526e80
https://pubmed.ncbi.nlm.nih.gov/15886524
https://pubmed.ncbi.nlm.nih.gov/15886524
Autor:
Jin-Wou Kim, So-Mi Kim Cho, Hong-Sig Sin, Young-Soy Rho, Si-Ho Park, Hye-Sook Han, Soo-Jong Um, Youn-Ja Kwon, Myoung-Soon Park
Publikováno v:
Bioorganicmedicinal chemistry. 11(17)
Retinol (vitamin A) is used as an antiwrinkle agent in the cosmetics industry. However, its photo-instability makes it unsuitable for use in general cosmetic formulations. To improve the photo-stability of retinol, three derivatives (3, 4, and 5) wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7942af759b05de4db3b0a3505cc7f92
https://pubmed.ncbi.nlm.nih.gov/12901928
https://pubmed.ncbi.nlm.nih.gov/12901928
Publikováno v:
ChemInform. 34
We successfully synthesized a 14-membered cyclic enamide of C3-epimauritine D from the cis-2,3-pyrrolidinediol derivative. Treatment of the pyrrolidinediol with nitrobenzonitrile in an SNAr reaction efficiently installed the desired aryl–alkyl ethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcd8172b07d91250e40dce3fb6d1195
https://doi.org/10.1002/chin.200326221
https://doi.org/10.1002/chin.200326221