Zobrazeno 1 - 10 of 155 pro vyhledávání: '"Myoung Ho Jang"'
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Akademický článek
Combined IgE neutralization and Bifidobacterium longum supplementation reduces the allergic response in models of food allergy
Autor: Seong Beom An, Bo-Gie Yang, Gyeonghui Jang, Do-Yeon Kim, Jiyoung Kim, Sung-Man Oh, Nahyun Oh, Sanghee Lee, Ji-Yeong Moon, Jeong-Ah Kim, Ji-Hyun Kim, Yoo-Jeong Song, Hye-Won Hyun, Jisoo Kim, Kyungwha Lee, Dajeong Lee, Min-Jung Kwak, Byung Kwon Kim, Young-Kyu Park, Chun-Pyo Hong, Jung Hwan Kim, Hye Seong Lim, Min Sook Ryu, Hyun-Tak Jin, Seung-Woo Lee, Yoon-Seok Chang, Hae-Sim Park, Young Chul Sung, Myoung Ho Jang
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
IgE is a critical component of the allergic response and therapeutic targeting can alleviate symptomology. Here the authors propose the combined use of Bifidobacterium longum and a FcεRIα extracellular domain linked to a IgD/IgG4 hybrid Fc domain f
Externí odkaz: https://doaj.org/article/c1edd33d00b34f5a8e3f07617351d63f
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6
Akademický článek
Degranulation of Mast Cells as a Target for Drug Development
Autor: Bo-Gie Yang, A-Ram Kim, Dajeong Lee, Seong Beom An, Yaein Amy Shim, Myoung Ho Jang
Publikováno v: Cells, Vol 12, Iss 11, p 1506 (2023)
Mast cells act as key effector cells of inflammatory responses through degranulation. Mast cell degranulation is induced by the activation of cell surface receptors, such as FcεRI, MRGPRX2/B2, and P2RX7. Each receptor, except FcεRI, varies in its e
Externí odkaz: https://doaj.org/article/6d2c627ff42b420696897a68ab5da040
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8
Akademický článek
Intestinal Epithelial Cell-Specific Deletion of PLD2 Alleviates DSS-Induced Colitis by Regulating Occludin
Autor: Chaithanya Chelakkot, Jaewang Ghim, Nirmal Rajasekaran, Jong-Sun Choi, Jung-Hwan Kim, Myoung Ho Jang, Young Kee Shin, Pann-Ghill Suh, Sung Ho Ryu
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Ulcerative colitis is a multi-factorial disease involving a dysregulated immune response. Disruptions to the intestinal epithelial barrier and translocation of bacteria, resulting in inflammation, are common in colitis. The mechanisms underl
Externí odkaz: https://doaj.org/article/e627bc7f4f0645b6bc20709220d51531
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10
Akademický článek
Parasitic nematode-induced CD4+Foxp3+T cells can ameliorate allergic airway inflammation.
Autor: Shin Ae Kang, Mi-Kyung Park, Min Kyoung Cho, Sang Kyun Park, Min Seong Jang, Bo-Gie Yang, Myoung Ho Jang, Dong-Hee Kim, Hak Sun Yu
Publikováno v: PLoS Neglected Tropical Diseases, Vol 8, Iss 12, p e3410 (2014)
The recruitment of CD4+CD25+Foxp3+T (Treg) cells is one of the most important mechanisms by which parasites down-regulate the immune system.We compared the effects of Treg cells from Trichinella spiralis-infected mice and uninfected mice on experimen
Externí odkaz: https://doaj.org/article/dd2999f51d3540e698e48c36287d0cfa
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