Structural and regulatory insights into the glideosome-associated connector from Toxoplasma gondii

Autor: Amit Kumar, Oscar Vadas, Nicolas Dos Santos Pacheco, Xu Zhang, Kin Chao, Nicolas Darvill, Helena Ø Rasmussen, Yingqi Xu, Gloria Meng-Hsuan Lin, Fisentzos A Stylianou, Jan Skov Pedersen, Sarah L Rouse, Marc L Morgan, Dominique Soldati-Favre, Stephen Matthews

Publikováno v: Kumar, A, Vadas, O, Dos Santos Pacheco, N, Zhang, X, Chao, K, Darvill, N, Rasmussen, H Ø, Xu, Y, Lin, G M-H, Stylianou, F A, Pedersen, J S, Rouse, S L, Morgan, M L, Soldati-Favre, D & Matthews, S 2023, ' Structural and regulatory insights into the glideosome-associated connector from Toxoplasma gondii ', eLife, vol. 12 . https://doi.org/10.7554/eLife.86049

The phylum of Apicomplexa groups intracellular parasites that employ substrate-dependent gliding motility to invade host cells, egress from the infected cells, and cross biological barriers. The glideosome-associated connector (GAC) is a conserved pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcdeb04e5a4e623d5f3af8c20553026
https://pure.au.dk/portal/da/publications/structural-and-regulatory-insights-into-the-glideosomeassociated-connector-from-toxoplasma-gondii(882484a3-51a4-4027-b7cc-e5abd3338998).html

Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity

Autor: Helder Maiato, Irène Wang, Amel Mettouchi, Jorge G Ferreira, Philippe Moreau, Elisa Vitiello, Martial Balland, Vanessa Nunes

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.52. ⟨10.1038/s41467-018-07965-6⟩
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
CIÊNCIAVITAE
Nature Communications, 2019, 10 (1), pp.52. ⟨10.1038/s41467-018-07965-6⟩

The presence of aberrant number of centrioles is a recognized cause of aneuploidy and hallmark of cancer. Hence, centriole duplication needs to be tightly regulated. It has been proposed that centriole separation limits centrosome duplication. The me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901d00e6b8152e5d6e2aee30d7c1111f
https://hal.archives-ouvertes.fr/hal-02063920/document

Human skeletal muscle fibre contractile properties and proteomic profile: adaptations to 3 weeks of unilateral lower limb suspension and active recovery

Autor: Brocca, L., Longa, E., Cannavino, J., Seynnes, O., de Vito, G., Mcphee, J., Narici, M., Pellegrino, M. A., Bottinelli, R.

Publikováno v: Journal of Physiology

Following disuse, muscle fibre function goes through adaptations such as a loss of specific force (PO/CSA) and an increase in unloaded shortening velocity, which could be a result of both quantitative changes (i.e. atrophy) and qualitative changes in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6a2ec8c771b16710becda9e8491de4bb
http://hdl.handle.net/11250/2404174

Functional characterization of vertebrate nonmuscle myosin IIB isoforms using Dictyostelium chimeric myosin II

Autor: Yuichi Hiratsuka, Akihiko Yamagishi, Keita Takahashi, Keiji Uchida, Masayuki Takahashi, Taro Q.P. Uyeda, Michio Yazawa

Publikováno v: The Journal of biological chemistry. 276(2):1034-1040

The alternatively spliced isoform of nonmuscle myosin II heavy chain B (MHC-IIB) with an insert of 21 amino acids in the actin-binding surface loop (loop 2), MHC-IIB(B2), is expressed specifically in the central nervous system of vertebrates. To exam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b3ec5a37e61767585c19e63739b71a
http://hdl.handle.net/2115/52172

Role of cortical tension in bleb growth

Autor: Ulrike Schulze, Jean-François Joanny, Guillaume Salbreux, Ewa K. Paluch, Jean-Yves Tinevez, Julia Roensch

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2009, 106 (44), pp.18581-18586. ⟨10.1073/pnas.0903353106⟩
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (44), pp.18581-18586. ⟨10.1073/pnas.0903353106⟩

International audience; Blebs are spherical membrane protrusions often observed during cell migration, cell spreading, cytokinesis, and apoptosis, both in cultured cells and in vivo. Bleb expansion is thought to be driven by the contractile actomyosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64af58f368da8ae44f9a13a33584038
https://hal-pasteur.archives-ouvertes.fr/pasteur-02616474