Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Myosin heavy chain kinase"'
Publikováno v:
Cells
Cells, Vol 10, Iss 1229, p 1229 (2021)
Volume 10
Issue 5
Cells, Vol 10, Iss 1229, p 1229 (2021)
Volume 10
Issue 5
Wound repair of cell membranes is essential for cell survival. Myosin II contributes to wound pore closure by interacting with actin filaments in larger cells
however, its role in smaller cells is unclear. In this study, we observed wound repair
however, its role in smaller cells is unclear. In this study, we observed wound repair
Autor:
Amanda Scherer, Michael A. Myre, Deborah Wessels, Daniel F. Lusche, Spencer Kuhl, David R. Soll
Publikováno v:
Developmental Biology. 394:24-38
Huntington׳s disease is a neurodegenerative disorder, attributable to an expanded trinucleotide repeat in the coding region of the human HTT gene, which encodes the protein huntingtin. These mutations lead to huntingtin fragment inclusions in the st
Autor:
Gaëtan Herinckx, Sébastien Pyr dit Ruys, Ewan M. Smith, Nusrat Hussain, Mark H. Rider, Didier Vertommen, Xuemin Wang, Christopher G. Proud
Publikováno v:
Biochemical Journal
The Biochemical journal, Vol. 442, no. 3, p. 681-692 (2012)
The Biochemical journal, Vol. 442, no. 3, p. 681-692 (2012)
eEF2K [eEF2 (eukaryotic elongation factor 2) kinase] phosphorylates and inactivates the translation elongation factor eEF2. eEF2K is not a member of the main eukaryotic protein kinase superfamily, but instead belongs to a small group of so-called α-
Autor:
Paul A. Steimle, Subhanjan Mondal, Francisco Rivero, Berthold Gassen, Angelika A. Noegel, Deenadayalan Bakthavatsalam
Publikováno v:
The Journal of Cell Biology
Ras guanine nucleotide exchange factor (GEF) Q, a nucleotide exchange factor from Dictyostelium discoideum, is a 143-kD protein containing RasGEF domains and a DEP domain. We show that RasGEF Q can bind to F-actin, has the potential to form complexes
Publikováno v:
European Journal of Biochemistry. 117:213-218
Chemotactic stimulation of the cellular slime mould Dictyostelium discoideum by cyclic AMP increases the incorporation of 32P into a 210-kDa polypeptide. This was determined in lysates prepared from stimulated and nonstimulated cells. Earlier results
Autor:
Shoshana Ravid, Ami Ben-Ya'acov
Publikováno v:
Journal of Biological Chemistry. 278:40032-40040
Epidermal growth factor (EGF) stimulation of prostate metastatic tumor cells results in transient phosphorylation and cellular localization of non-muscle myosin heavy chain II-B (NMHC II-B) with kinetics similar to those seen in chemotaxis. We demons
Autor:
Christian Bittner, Johannes Pleiner, Michael Quittan, Bärbel Gohlsch, Martin Nuhr, Günther F. Wiesinger, Dirk Pette, Veronika Fialka-Moser, Richard Crevenna
Publikováno v:
European Journal of Applied Physiology. 89:202-208
The present study was undertaken to investigate in a randomized controlled trial the effects of chronic (10 weeks, 4 h per day, 7 days per week) low-frequency (15 Hz) stimulation (CLFS) of the knee extensor and hamstring muscles of both legs in healt
Autor:
Mark V. Polyakov, Quint G. Medley, Graham P. Côté, Thomas T. Egelhoff, Shigehiko Yumura, Paul A. Steimle, Brian Leppert
Publikováno v:
Current Biology. 11:708-713
Nonmuscle myosin II plays fundamental roles in cell body translocation during migration and is typically depleted or absent from actin-based cell protrusions such as lamellipodia, but the mechanisms preventing myosin II assembly in such structures ha
Publikováno v:
Journal of Biological Chemistry. 276:6853-6860
Myosin heavy chain kinase (MHCK) A phosphorylates mapped sites at the C-terminal tail of Dictyostelium myosin II heavy chain, driving disassembly of myosin filaments both in vitro and in vivo. MHCK A is organized into three functional domains that in
Publikováno v:
Digestive Diseases and Sciences. 46:1629-1632