Zobrazeno 1 - 10
of 3 405
pro vyhledávání: '"Myosin head"'
Publikováno v:
The Journal of Cell Biology, 1999 Dec . 147(7), 1385-1389.
Externí odkaz:
https://www.jstor.org/stable/1619640
Autor:
Marcus Henze, Weikang Ma, Robert L. Anderson, Thomas C. Irving, Henry M Gong, Carlos del Rio, Fiona L. Wong
Publikováno v:
Circ Res
Rationale: Myofilament length-dependent activation (LDA) is the key underlying mechanism of cardiac heterometric autoregulation, commonly referred as the Frank-Starling Law of the heart. Although alterations in LDA are common in cardiomyopathic state
Autor:
Romina Vargiu, Raffaella Isola, Francesco Loy, Francesca Broccia, Michela Isola, Alberto Casti
Publikováno v:
Experimental Physiology
New findings What is the central question of this study? In the papillary muscle from type I diabetic rats, does diabetes-associated altered ventricular function result from changes of acto-myosin interactions and are these modifications attributable
Publikováno v:
J Phys Chem Lett
The movement of tropomyosin over filamentous actin regulates the cross-bridge cycle of the thick with thin filament of cardiac muscle by blocking and revealing myosin binding sites. Tropomyosin exists in three, distinct equilibrium states with one st
Publikováno v:
Biophysics. 66:304-309
The temperature dependences of the tension and stiffness of actively contracting single fibers of the rabbit slow muscle (m. soleus) were studied using the Joule temperature jump. Differences in the characteristics of the fibers of the rabbit fast (m
Autor:
Christopher Solís, Brenda Russell
Publikováno v:
J Muscle Res Cell Motil
A transduced mechanical signal arriving at its destination in muscle alters sarcomeric structure and function. A major question addressed is how muscle mass and tension generation are optimized to match actual performance demands so that little energ
Autor:
Jamie R. Johnston, Paul M.L. Janssen, Michelle Rodriquez Garcia, Rakesh K. Singh, Michelle S. Parvatiyar, Jose R. Pinto, Matthew C. Childers, Huan He, Elizabeth A. Brundage, Michael Regnier, Brandon J. Biesiadecki, Amanda L. Wacker, Maicon Landim-Vieira, P. Bryant Chase, Bryan A Whitson
Publikováno v:
eLife. 11
Phosphorylation and acetylation of sarcomeric proteins are important for fine-tuning myocardial contractility. Here, we used bottom-up proteomics and label-free quantification to identify novel post-translational modifications (PTMs) on beta-myosin h
Publikováno v:
Eakins, F, Knupp, C & Squire, J M 2019, ' Monitoring the Myosin Crossbridge Cycle in Contracting Muscle : Steps towards ‘Muscle the Movie’. ', Journal of Muscle Research and Cell Motility, vol. 40, pp. 77-91 . https://doi.org/10.1007/s10974-019-09543-9
Journal of Muscle Research and Cell Motility
Journal of Muscle Research and Cell Motility
Some vertebrate muscles (e.g. those in bony fish) have a simple lattice A-band which is so well ordered that low-angle X-ray diffraction patterns are sampled in a simple way amenable to crystallographic techniques. Time-resolved X-ray diffraction thr
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
Familial hypertrophic cardiomyopathy (FHC) is the most frequent inherited cardiac disease. It has been related to numerous mutations in many sarcomeric and even some non-sarcomeric proteins. So far, however, no common mechanism has been identified by
Externí odkaz:
https://doaj.org/article/f6d63c6d948d430ea4391c4cda7af655
Autor:
K. W. Ranatunga, Gerald Offer
Publikováno v:
Biophys J
It is controversial whether the phosphate (Pi) release step in the cross-bridge cycle occurs before or after the first tension-generating step and whether it is fast or slow. We have therefore modified our previous model of the frog cross-bridge cycl