Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Myong Jung Kim"'
Enzyme-assisted high throughput sequencing of an expanded genetic alphabet at single base resolution
Autor:
Bang Wang, Kevin M. Bradley, Myong-Jung Kim, Roberto Laos, Cen Chen, Dietlind L. Gerloff, Luran Manfio, Zunyi Yang, Steven A. Benner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract With just four building blocks, low sequence information density, few functional groups, poor control over folding, and difficulties in forming compact folds, natural DNA and RNA have been disappointing platforms from which to evolve recepto
Externí odkaz:
https://doaj.org/article/025d698ec3364749b2c91f336ff28175
Autor:
Hinako Kawabe, Christopher A. Thomas, Shuichi Hoshika, Myong-Jung Kim, Myong-Sang Kim, Logan Miessner, Nicholas Kaplan, Jonathan M. Craig, Jens H. Gundlach, Andrew H. Laszlo, Steven A. Benner, Jorge A. Marchand
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The 4-letter DNA alphabet (A, T, G, C) as found in Nature is an elegant, yet non-exhaustive solution to the problem of storage, transfer, and evolution of biological information. Here, we report on strategies for both writing and reading DNA
Externí odkaz:
https://doaj.org/article/089902ffac324fbb99cc17565a7c89f5
Autor:
Yubing Li, Clay Abraham, Oleg Suslov, Ozlem Yaren, Ryan W. Shaw, Myong-Jung Kim, Shuo Wan, Philippe Marliere, Steven A. Benner
Publikováno v:
ACS Synthetic Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b8281b642bef5aa8c6caa028dece420
https://doi.org/10.1021/acssynbio.3c00060
https://doi.org/10.1021/acssynbio.3c00060
Autor:
Isha Singh, Nicole A. Leal, Christopher Switzer, Shuichi Hoshika, Steven A. Benner, Millie M. Georgiadis, Robert W. Molt, Myong Sang Kim, Hyo Joong Kim, Myong Jung Kim
Publikováno v:
Journal of the American Chemical Society. 140:11655-11660
According to the iconic model, the Watson-Crick double helix exploits nucleobase pairs that are both size complementary (big purines pair with small pyrimidines) and hydrogen bond complementary (hydrogen bond donors pair with hydrogen bond acceptors)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e89d6cf86c3d702e47b161bd57206b
https://doi.org/10.1021/jacs.8b05042
https://doi.org/10.1021/jacs.8b05042
Autor:
Shuichi Hoshika, Myong Jung Kim, Steven A. Benner, Robert W. Molt, Isha Singh, Millie M. Georgiadis
Publikováno v:
ACS Synthetic Biology. 6:2118-2129
A goal of synthetic biology is to develop new nucleobases that retain the desirable properties of natural nucleobases at the same time as expanding the genetic alphabet. The non-standard Watson-Crick pair between imidazo[1,2-a]-1,3,5-triazine-2(8H)-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eec48899e24ec59720cdd58249edf84
https://doi.org/10.1021/acssynbio.7b00150
https://doi.org/10.1021/acssynbio.7b00150
Autor:
Xiaoyu Wang, Myong-Jung Kim, Steven A. Benner, Shuichi Hoshika, Raymond J. Peterson, Jason D. Kahn
Publikováno v:
ACS Synthetic Biology. 6:782-792
Synthetic nucleobases presenting non-Watson-Crick arrangements of hydrogen bond donor and acceptor groups can form additional nucleotide pairs that stabilize duplex DNA independent of the standard A:T and G:C pairs. The pair between 2-amino-3-nitropy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f05fb503c40714e91ab0eaacbbc861
https://doi.org/10.1021/acssynbio.6b00224
https://doi.org/10.1021/acssynbio.6b00224
Autor:
Christian B. Winiger, Mariko F. Matsuura, Myong-Jung Kim, Steven A. Benner, Jennifer D. Moses, Shuichi Hoshika, Dietlind L. Gerloff, Ryan W. Shaw
Publikováno v:
Biochemistry
In addition to completing the Watson-Crick nucleobase matching "concept" (big pairs with small, hydrogen bond donors pair with hydrogen bond acceptors), artificially expanded genetic information systems (AEGIS) also challenge DNA polymerases with a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44e474647ba3da046907a4e606b4ff1
https://doi.org/10.1021/acs.biochem.6b00533
https://doi.org/10.1021/acs.biochem.6b00533
Autor:
Myong-Jung Kim, Shuichi Hoshika, Nilesh B. Karalkar, Steven A. Benner, Hyo-Joong Kim, Myong-Sang Kim, Jennifer D. Moses, Ryan W. Shaw, Mariko F. Matsuura
Publikováno v:
ACS Synthetic Biology. 5:234-240
One frontier in synthetic biology seeks to move artificially expanded genetic information systems (AEGIS) into natural living cells and to arrange the metabolism of those cells to allow them to replicate plasmids built from these unnatural genetic sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae73ea5c50600b8a17b0c26fd68f2e7
https://doi.org/10.1021/acssynbio.5b00172
https://doi.org/10.1021/acssynbio.5b00172
Autor:
Nilesh B. Karalkar, Hyo Joong Kim, Andrew D. Ellington, Myong Jung Kim, Steven A. Benner, Shuichi Hoshika, John SantaLucia, Norman E. Watkins, Joseph A. Piccirilli, Alison M. Bates, Nicole A. Leal, Holly A. SantaLucia, Adam J. Meyer, Millie M. Georgiadis, Myong Sang Kim, Saurja DasGupta
Publikováno v:
Biochemistry
Steve Benner and collaborators have recently reported an analysis of DNA containing eight nucleotide letters – the four natural letters dG, dC, dA, and dT, and four additional letters, called dP, dZ, dS, and dB. Their analysis demonstrates that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652536020849a6eb7aeb3f5bb75a8039
https://pubmed.ncbi.nlm.nih.gov/31117391
https://pubmed.ncbi.nlm.nih.gov/31117391
Autor:
Joseph A. Piccirilli, Sandip A. Shelke, Yaming Shao, Armando R. Hernández, Zunyi Yang, Hyo-Joong Kim, Julien Herrou, Steven A. Benner, Myong-Jung Kim, Shuichi Hoshika
Publikováno v:
Angewandte Chemie. 127:9991-9994
As one of its goals, synthetic biology seeks to increase the number of building blocks in nucleic acids. While efforts towards this goal are well advanced for DNA, they have hardly begun for RNA. Herein, we present a crystal structure for an RNA ribo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191f452d11063c0fd14f40a1982f57ed
https://doi.org/10.1002/ange.201504731
https://doi.org/10.1002/ange.201504731