Eosinophils improve cardiac function after myocardial infarction

Autor: Dafeng Yang, Xian Zhang, Dazhu Li, Axel Cosmus Pyndt Diederichsen, Yunzhe Wang, Tianxiao Liu, Zhiyong Deng, Chongzhe Yang, Cong-Lin Liu, Lars Melholt Rasmussen, Jing Liu, Jing Wang, Peter Libby, Francis W. Luscinskas, Gail Newton, Wenqian Fang, Lijun Liu, Qin Huang, Guo-Ping Shi, Galina K. Sukhova, Junli Guo, Jes S. Lindholt, Jie Li

Publikováno v: Liu, J, Yang, C, Liu, T, Deng, Z, Fang, W, Zhang, X, Li, J, Huang, Q, Liu, C, Wang, Y, Yang, D, Sukhova, G K, Lindholt, J S, Diederichsen, A, Rasmussen, L M, Li, D, Newton, G, Luscinskas, F W, Liu, L, Libby, P, Wang, J, Guo, J & Shi, G-P 2020, ' Eosinophils improve cardiac function after myocardial infarction ', Nature Communications, vol. 11, 6396 . https://doi.org/10.1038/s41467-020-19297-5
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Liu, J, Yang, C, Liu, T, Deng, Z, Fang, W, Zhang, X, Li, J, Huang, Q, Liu, C, Wang, Y, Yang, D, Sukhova, G K, Lindholt, J S, Diederichsen, A, Rasmussen, L M, Li, D, Newton, G, Luscinskas, F W, Liu, L, Libby, P, Wang, J, Guo, J & Shi, G P 2020, ' Eosinophils improve cardiac function after myocardial infarction ', Nature Communications, vol. 11, 6396 . https://doi.org/10.1038/s41467-020-19297-5

Clinical studies reveal changes in blood eosinophil counts and eosinophil cationic proteins that may serve as risk factors for human coronary heart diseases. Here we report an increase of blood or heart eosinophil counts in humans and mice after myoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017a224017796428c2ef5b86d0797285
https://pubmed.ncbi.nlm.nih.gov/33437041

Inhibition of the Hypoxia-Inducible Factor 1α-Induced Cardiospecific HERNA1 Enhance-Templated RNA Protects From Heart Disease

Autor: Peter Mirtschink, Rahul Sharma, Geetha Rossi, Sanjay Khadayate, Corinne Berthonneche, Eman Hagag, Wilhelm Krek, Corinne Bischof, Jaya Krishnan, Thierry Pedrazzini, Samuel Sossalla, Phillip Grote, Shuyang Traub, Niklaus Fankhauser, Alexandre Sarre, Sebastian Stehr, Stefanie Dimmeler, Minh Duc Pham

Publikováno v: Circulation, vol. 139, no. 24, pp. 2778-2792
Circulation
Circulation, 139 (24)

Supplemental Digital Content is available in the text.
Background: Enhancers are genomic regulatory elements conferring spatiotemporal and signal-dependent control of gene expression. Recent evidence suggests that enhancers can generate noncodin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d25d4a747aa8a59989af7a0718498f
https://serval.unil.ch/resource/serval:BIB_BAE7C7F2C66F.P001/REF.pdf

An autopsy case of necrotizing eosinophilic myocarditis causing left ventricular wall rupture

Autor: Kleio Fragkouli, Vassiliki A. Boumba, Theodore Vougiouklakis, Antigoni Mitselou, Labros Michalis

Publikováno v: Forensic Science, Medicine, and Pathology. 7:350-354

Acute necrotizing eosinophilic myocarditis (ANEM) is a rare entity with sudden onset and rapidly progressive course, usually leading to a fatal outcome. It is characterized by focal or widespread myocyte necrosis. The entity's clinical presentation i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bad7bdee45efe6847c6856f924a3ebe
https://doi.org/10.1007/s12024-011-9235-8

Association of depressed cardiac gp130-mediated antiapoptotic pathways with stimulated cardiomyocyte apoptosis in hypertensive patients with heart failure

Autor: Susana Ravassa, Javier Díez, Begoña López, Arantxa González, Javier Beaumont, Mariano Larman, Iñigo Loperena, Ramón Querejeta

OBJECTIVE: To investigate whether the glycoprotein (gp130)-mediated survival pathway, which protects cardiomyocytes from apoptosis, is depressed in left ventricular hypertrophy hypertensive patients with chronic heart failure. METHODS: Transvenous en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29773cc2c07211ccd1a60d5500863c5
https://hdl.handle.net/10171/21863

Clinical implications of apoptosis in hypertensive heart disease

Autor: Begoña López, Susana Ravassa, Arantxa González, M.A. Fortuño, Javier Díez

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
instname

the essential criterion in defining hypertensive heart disease is a greater than normal heart mass in the absence of a cause other than arterial hypertension. However, it is now accepted that besides left ventricular hypertrophy, alterations in diast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b777b2cadb85c6e97e3ae03f481b3dc
https://pubmed.ncbi.nlm.nih.gov/12679323