Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Myo-inositol monophosphatase"'
Publikováno v:
Genes; Volume 8; Issue 7; Pages: 179
Genes, Vol 8, Iss 7, p 179 (2017)
Genes
Genes, Vol 8, Iss 7, p 179 (2017)
Genes
Inositol is a cyclic polyol that is involved in various physiological processes, including signal transduction and stress adaptation in plants. l-myo-inositol monophosphatase (IMPase) is one of the metal-dependent phosphatase family members and catal
Autor:
Hui Xiao, Hui-rong Dai, Li Li, Yuping Wang, Jian-Min Yuan, Lihui Lin, Juan Wang, Xia Peng, Jia Li, Sheng Huang, Fei Li
Publikováno v:
Journal of Cellular and Molecular Medicine
Previous studies with biological and genetic evidence indicate that the myo‐inositol monophosphatase 2 (IMPA2) gene may influence schizophrenia. We performed a genetic association study in Han Chinese cohorts. Five single nucleotide polymorphisms w
Akademický článek
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Autor:
Eduard Vieta, Estela Salagre, Bárbara Arias, Julio Bobes, María Paz García-Portilla, Lorena de la Fuente, Pilar A. Saiz, Iria Grande, Y. Tomioka, Susana Gomes-da-Costa, Esther Jiménez, Marina Mitjans, Antoni Benabarre, Victoria Ruíz
Publikováno v:
Journal of affective disorders. 232
Introduction The age at onset of bipolar disorder (BD) has significant implications for severity, duration of affective episodes, response to treatment, and psychiatric comorbidities. It has been suggested that early-onset BD (EO-BD) could represent
Publikováno v:
Genetics
Although neurons are highly polarized, how neuronal polarity is generated remains poorly understood. An evolutionarily conserved inositol-producing enzyme myo-inositol monophosphatase (IMPase) is essential for polarized localization of synaptic molec
Publikováno v:
Moscow University Chemistry Bulletin. 62:246-248
A new class of structural analogues of inositol (polyhydroxycycloheptanes, homoinositols) is proposed. 2,3,4,4-Tetrachloro-8-octabicyclo[3.2.1]octadiene-2,6, the adduct of the Diels-Alder reaction between tetracyclopropene and furan, is suggested as
Publikováno v:
Tetrahedron Letters. 39:4009-4012
Arylalkylmonofluorophosphonates were prepared by condensation of arylalkylaldehydes with the lithium salt of diethyl 1-fluoro-1-(trimethylsilyl)-methylphosphonate. Reduction and hydrolysis sequences gave the final products. These compounds do not inh
Publikováno v:
Tetrahedron Letters. 38:5245-5248
Concomitant deprotection/spiro-heteroannulation of 6 utilizing (EtO)3SiI was exploited for the asymmetric total synthesis of the title tetracyclic terpenoid whose structure was revised to 13.
Autor:
Andrew Sharpe, Raymond Baker, John R. Atack, Tamara Ladduwahetty, Stephen Robert Fletcher, Martin Richard Teall
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:141-146
From a series of 4-hydroxyphenoxymethylene bisphosphonic acid derivatives 1-(4-Hydroxyphenoxy)-1-(methyl)methylenebisphosphonic acid has been identified as a structurally simple, competitive, inhibitor of myo -inositol monophosphatase (IC 50 , 0.33
Akademický článek
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