Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mylyne Tham"'
Autor:
Christopher A. Robinson, Claudia F. Lucchinetti, Yong Guo, Reginald C. Adiele, Samuel M. Webb, Wolfgang Brück, Kendra L Furber, M. Jake Pushie, Hans Lassmann, Joseph E. Parisi, Stephen D. Weigand, Josa M. Frischer, Mylyne Tham, Patrick D. Fitz-Gibbon, Bogdan F. Gh. Popescu
Publikováno v:
Annals of Neurology
OBJECTIVE Multiple sclerosis (MS) is a heterogeneous inflammatory demyelinating disease. Iron distribution is altered in MS patients' brains, suggesting iron liberation within active lesions amplifies demyelination and neurodegeneration. Whether the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009877c88f657d7eeeb0a888995fb8c7
https://doi.org/10.1002/ana.25974
https://doi.org/10.1002/ana.25974
Autor:
Melanie E. M. Kelly, Mylyne Tham, Robert B. Laprairie, Eileen M. Denovan-Wright, Orhan Yilmaz, Mariam Alaverdashvili
Publikováno v:
British Journal of Pharmacology. 176:1455-1469
Background and purpose We sought to understand why (-)-cannabidiol (CBD) and (-)-cannabidiol-dimethylheptyl (CBD-DMH) exhibit distinct pharmacology, despite near identical structures. Experimental approach HEK293A cells expressing either human type 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44215bfda0d977b77f80b48108f116a3
https://doi.org/10.1111/bph.14440
https://doi.org/10.1111/bph.14440
Autor:
Mylyne, Tham, Orhan, Yilmaz, Mariam, Alaverdashvili, Melanie E M, Kelly, Eileen M, Denovan-Wright, Robert B, Laprairie
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: We sought to understand why (−)‐cannabidiol (CBD) and (−)‐cannabidiol‐dimethylheptyl (CBD‐DMH) exhibit distinct pharmacology, despite near identical structures. EXPERIMENTAL APPROACH: HEK293A cells expressing eithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3803e50ac69d1d3aa39698434be10c1
https://pubmed.ncbi.nlm.nih.gov/29981240
https://pubmed.ncbi.nlm.nih.gov/29981240
Autor:
Claudia F. Lucchinetti, Mylyne Tham, Bogdan F.G.H. Popescu, Reginald C. Adiele, Christopher A. Robinson
Publikováno v:
Acta Neuropathologica Communications
Acute hemorrhagic leukoencephalitis (AHL) is a fulminant demyelinating disease of unknown etiology. Most cases are fatal within one week from onset. AHL pathology varies with the acuteness of disease. Hemorrhages, vessel fibrinoid necrosis, perivascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86459b75c2bf834657d341d357caffb7
https://doi.org/10.1186/2051-5960-2-52
https://doi.org/10.1186/2051-5960-2-52
Autor:
Elizabeth Norton, Stephen Pojen Denq, Claudia F. Lucchinetti, Sarah Gheuens, Xin Dang, Michael Marvi, Christian Wüthrich, Mylyne Tham, Joseph E. Parisi, Igor J. Koralnik, Bogdan F. Gh. Popescu, Ronald Ziman
Publikováno v:
Journal of neuropathology and experimental neurology. 72(11)
Natalizumab, a monoclonal antibody directed against α4 integrins, has, to date, been associated with 399 cases of progressive multifocal leukoencephalopathy (PML) worldwide in patients receiving treatment for multiple sclerosis (MS). Because of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad56f1c521d1399581d9d1f40e1a37b
https://pubmed.ncbi.nlm.nih.gov/24128680
https://pubmed.ncbi.nlm.nih.gov/24128680
Autor:
Imke Metz, Samuel M. Webb, Graham N. George, Claudia F. Lucchinetti, Bogdan F. Gh. Popescu, Josa M. Frischer, Joseph E. Parisi, Patrick D. Fitz-Gibbon, Reginald C. Adiele, Hans Lassmann, Susan Nehzati, Mylyne Tham, Wolfgang Brück, Guo Yong, Stephen D. Weigand, Christopher A. Robinson, Ingrid J. Pickering, Simon Hametner
Publikováno v:
Acta Neuropathologica
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) in which oligodendrocytes, the CNS cells that stain most robustly for iron and myelin are the targets of injury. Metals are essential for norm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21af6568fcc7860da1f8d1f0b6d0b393