Type 2 diabetes, breast cancer specific and overall mortality: Associations by metformin use and modification by race, body mass, and estrogen receptor status.

Autor: Kyung Na Lee, Mylin A Torres, Alyssa N Troeschel, Jiabei He, Keerthi Gogineni, Lauren E McCullough

Publikováno v: PLoS ONE, Vol 15, Iss 5, p e0232581 (2020)

INTRODUCTION:While type 2 diabetes (T2D) has been associated with increased all-cause mortality among women diagnosed with breast cancer (BC), the association between T2D and breast cancer-specific (BCS) mortality is unresolved. The goal of this stud

Externí odkaz: https://doaj.org/article/2bfcb013b7044112aabb41569b5717ff

DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases

Autor: Matthias Wielscher, Pooja R. Mandaviya, Brigitte Kuehnel, Roby Joehanes, Rima Mustafa, Oliver Robinson, Yan Zhang, Barbara Bodinier, Esther Walton, Pashupati P. Mishra, Pascal Schlosser, Rory Wilson, Pei-Chien Tsai, Saranya Palaniswamy, Riccardo E. Marioni, Giovanni Fiorito, Giovanni Cugliari, Ville Karhunen, Mohsen Ghanbari, Bruce M. Psaty, Marie Loh, Joshua C. Bis, Benjamin Lehne, Nona Sotoodehnia, Ian J. Deary, Marc Chadeau-Hyam, Jennifer A. Brody, Alexia Cardona, Elizabeth Selvin, Alicia K. Smith, Andrew H. Miller, Mylin A. Torres, Eirini Marouli, Xin Gào, Joyce B. J. van Meurs, Johanna Graf-Schindler, Wolfgang Rathmann, Wolfgang Koenig, Annette Peters, Wolfgang Weninger, Matthias Farlik, Tao Zhang, Wei Chen, Yujing Xia, Alexander Teumer, Matthias Nauck, Hans J. Grabe, Macus Doerr, Terho Lehtimäki, Weihua Guan, Lili Milani, Toshiko Tanaka, Krista Fisher, Lindsay L. Waite, Silva Kasela, Paolo Vineis, Niek Verweij, Pim van der Harst, Licia Iacoviello, Carlotta Sacerdote, Salvatore Panico, Vittorio Krogh, Rosario Tumino, Evangelia Tzala, Giuseppe Matullo, Mikko A. Hurme, Olli T. Raitakari, Elena Colicino, Andrea A. Baccarelli, Mika Kähönen, Karl-Heinz Herzig, Shengxu Li, BIOS consortium, Karen N. Conneely, Jaspal S. Kooner, Anna Köttgen, Bastiaan T. Heijmans, Panos Deloukas, Caroline Relton, Ken K. Ong, Jordana T. Bell, Eric Boerwinkle, Paul Elliott, Hermann Brenner, Marian Beekman, Daniel Levy, Melanie Waldenberger, John C. Chambers, Abbas Dehghan, Marjo-Riitta Järvelin

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Chronic inflammation, marked by C-reactive protein, has been associated with changes in methylation, but the causal relationship is unclear. Here, the authors perform a Epigenome-wide association meta-analysis for C-reactive protein levels and find t

Externí odkaz: https://doaj.org/article/715a1a2d6b1f44f19a7bcf745876ed05

Prolonging the life of people with metastatic breast cancer in routine clinical practice by adding palbociclib to an aromatase inhibitor from a real-world database analysis: a plain language summary

Autor: Hope S Rugo, Adam Brufsky, Xianchen Liu, Benjamin Li, Lynn McRoy, Connie Chen, Rachel M Layman, Massimo Cristofanilli, Mylin A Torres, Giuseppe Curigliano, Richard S Finn, Angela DeMichele

Publikováno v: Future Oncology. 19:489-498

What is this summary about? This is a summary of an article about a study called “P-REALITY X” that was published in the medical journal npj Breast Cancer in October 2022. “P-REALITY X” stands for Palbociclib REAl-world first-LIne comparaTive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::467363b9001c3bb605d5d07e09811739
https://doi.org/10.2217/fon-2022-1192

Comparison of different cell type correction methods for genome-scale epigenetics studies

Autor: Akhilesh Kaushal, Hongmei Zhang, Wilfried J. J. Karmaus, Meredith Ray, Mylin A. Torres, Alicia K. Smith, Shu-Li Wang

Publikováno v: BMC Bioinformatics, Vol 18, Iss 1, Pp 1-12 (2017)

Abstract Background Whole blood is frequently utilized in genome-wide association studies of DNA methylation patterns in relation to environmental exposures or clinical outcomes. These associations can be confounded by cellular heterogeneity. Algorit

Externí odkaz: https://doaj.org/article/82eadd35e3c449ccbe56af712749e4b6

Quantitative ultrasound radiomics for monitoring radiation-induced toxicity following breast radiotherapy

Autor: Jing Wang, Boran Zhou, Mylin A. Torres, Xiaofeng Yang, Tian Liu

Publikováno v: Medical Imaging 2023: Computer-Aided Diagnosis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94ab629dd235572cb2a7fdc13b69838d
https://doi.org/10.1117/12.2654081